Clinical trials: Growth & Development
Health Behavior, Health Knowledge, Attitudes, Practice
CircaHealth Development and Evaluation
This study evaluates the feasibility, acceptability, and efficacy of an online education course about circadian rhythms and health.
- Conditions
- Health Behavior, Health Knowledge, Attitudes, Practice, Circadian Rhythm
- Trial name
- NCT03835572
- Testing
- CircaHealth: a course on circadian rhythms and health, Sleep hygiene materials
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Miami
Autism
Treatment for Children With Autism and Anxiety
Children with high-functioning autism spectrum disorders (ASD) are at high risk for developing significant anxiety symptoms. Cognitive behavior therapies (CBT) are frequently used for children with anxiety symptoms with good…
- Trial name
- NCT01727466
- Testing
- Facing Your Fears
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Facial Angiofibromas
Topical Everolimus in Patients With Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is a rare genetic multisystem disorder characterized by the development of hamartomas in several organs (e.g. brain, heart, kidney, liver, lung), and skin in more than 90% of cases.
- Trial name
- EVEROST (NCT02860494)
- Testing
- Everolimus
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Drug-resistant Focal Epilepsies in Pediatric Population
Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
Brain somatic mutations are increasingly recognized as a major cause of focal epilepsies. These include mTOR pathway mutations underlying cortical malformations such as focal cortical dysplasia and hemimegalencephaly, and SLC35A2…
- Trial name
- GENEPHY (NCT02890641)
- Testing
- Sampling of blood, frozen resected tissues, and cerebrospinal fluid (CSF)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Precocious Puberty, Overweight and Obesity
Overweight and Obesity and Puberty Development Cohort Study
Precocious puberty and childhood overweight and obesity are important public health problems that both had adverse effects, which including psychological symptom in childhood, short final height or reproductive dysfunction in…
- Trial name
- NCT04113070
- Testing
- Anthropometric measuring, Growth environment evaluation
- Where
- China
- Volunteers
- 14,100 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Myopia, Large Language Model
Development and Validation of a Large Language Model-based Myopia Assistant System
Myopia is a rapidly growing global health concern, and there is an urgent need for advanced tools that can facilitate personalized healthcare strategies.
- Trial name
- NCT06607822
- Testing
- A patient-centered assistant system based on Large-Language Model (LLM)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)
ML-004-002 is a multi-center, randomized, double-blind, parallel-group, placebo-controlled study that will enroll approximately 150 adolescent and adult subjects with ASD.
- Trial name
- NCT05081245
- Testing
- ML-004 (IR)/(ER) tablet
- Where
- 29 sites in United States, Australia and 1 more
- Volunteers
- 168 people
- Sponsor
- MapLight Therapeutics
Diabetes
A Series of Systematic Reviews and Meta-analyses of the Effect of Vegetarian/Vegan Diets on Cardiometabolic Risk
Vegetarian and vegan diets have been shown to reduce chronic disease risk, including diabetes and cardiovascular disease, as well as several cardiometabolic risk factors.
- Trial name
- NCT02600377
- Testing
- Vegetarian diet
- Volunteers
- 1 people
- Sponsor
- University of Toronto
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
Tau/P-Tau and Neurocognitive Outcomes in Children
The proposed studies are aimed to measure Tau and P-Tau levels in pre- and postoperative blood, urine, feces and saliva, as well as to assess pre- and postoperative neurocognitive function in children (3 to 5 years old) who will…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
- Trial name
- NCT03511729
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Spinal Muscular Atrophy
Development of a Multidisciplinary Network for Clinical and Laboratory Research for SMA
The goal of this observational study is to to establish profiles of clinical progression in patients affected by the different types of SMA (type I, II and III) treated with the currently approved drugs using a structured battery…
- Trial name
- NCT05866939
- Volunteers
- 400 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Development of Side Effects From Betaxolol
Topical Betaxolol for the Prevention of Retinopathy of Prematurity
We hypothesize that topical betaxolol will reduce the development of severe retinopathy of prematurity.
- Trial name
- NCT01660620
- Testing
- Betaxolol, topical betaxolol
- Volunteers
- 23 people
- Sponsor
- Smith-Kettlewell Eye Research Institute
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
GroundsKeeper: A Qualitative Study of Applied Game-based Interactives in Special Education Programs
The purpose of this study is to examine the use of, and reaction to, one particular software application(GroundsKeeper) delivered on unique platform - Sifteo cubes (www.sifteo.com).
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Pervasive Developmental Disorder, Asperger's Disorder
- Trial name
- NCT01808066
- Testing
- Groundskeeper
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- CogCubed, Corp
Autism
Intranasal Oxytocin Treatment for Social Deficits in Children With Autism
Autism is a pervasive developmental disorder characterized by core deficits in social behavior and communication, and the presence of repetitive or stereotyped behaviors.
- Trial name
- NCT01624194
- Testing
- Oxytocin nasal spray
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Stanford University
Autism, Autistic Disorder
Randomized Control Trial of Using Tongue Acupuncture in Autistic Spectrum Disorder Using PET Scan for Clinical Correlation
We aimed to use Tongue Acupuncture (TAC) to assess for any change in brain function.
- Trial name
- NCT00355329
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Influenza, Influenza Immunisation
Development of Childhood Anti-Influenza Immunity
This study is a prospective surveillance of the immune response to seasonal vaccination in healthy children. The study will enroll a total of approximately 220 subjects.
- Trial name
- NCT03673345
- Testing
- Influenza Virus Quadrivalent Inactivated Vaccine
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Metabolic Syndrome X
OPUS School Meal Study
The aim of this randomized crossover study, is to investigate the effect of school meals based on a sustainable New Nordic Diet on growth, learning abilities, well-being, sleep quality, physical activity and risk markers of…
- Trial name
- NCT01457794
- Testing
- School meals based on the principles of the New Nordic Diet
- Where
- Denmark
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Arne Astrup
Autism Spectrum Disorder, Repetitive Compulsive Behavior
Family-Implemented Treatment on the Behavioral Inflexibility of Children With Autism
The overall goal of this project is to determine whether a new form of family-based treatment for repetitive and inflexible behaviors, delivered using videoconferencing technology, can counter any negative effects of those…
- Trial name
- FITBI (NCT05125003)
- Testing
- FITBI, Parental Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Tuberous Sclerosis Complex
Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)
The investigators are enrolling 3-12 month old infants with a diagnosis of tuberous sclerosis complex (TSC) for a new study on early markers of autism.
- Trial name
- NCT01780441
- Where
- 5 sites in United States
- Volunteers
- 166 people
- Sponsor
- Boston Children's Hospital
Paraganglioma, Pheochromocytoma
Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Phaeochromocytomas and paragangliomas (PPGLs) are tumours of the adrenal medulla and extra-adrenal sympathetic nervous system, some which can become metastatic. It is a very rare disease and the tumours are often detected late.
- Conditions
- Paraganglioma, Pheochromocytoma, Genetic Predisposition to Disease, Pathology
- Trial name
- PPGL-Pred (NCT04788927)
- Where
- 2 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders
This study will examine the effectiveness of riluzole for treating Obsessive-Compulsive Disorder in Youth, Including those with Autism Spectrum Disorders.
- Conditions
- Obsessive-Compulsive Disorder, Autism Spectrum Disorder, Autism, Asperger Disorder
- Trial name
- NCT00251303
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Mental Health (NIMH)
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