Clinical trials: Growth & Development
Tuberous Sclerosis
JASPER Early Intervention for Tuberous Sclerosis
The investigators are running an intervention study for young children with Tuberous Sclerosis Complex (TSC). The study will include free play-based behavioral intervention administered remotely that may improve social and…
- Trial name
- JETS (NCT03422367)
- Testing
- JASPER
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of California, Los Angeles
Premature Birth
2-Brain Regulation to Achieve Improved Neuroprotection During Early Development
Each year 15 million infants are born preterm (PT). Even without severe comorbidities, they are exposed to sensory stress during the Neonatal Intensive Care Unit (NICU) stay and are at greater risk of neurodevelopmental problems…
- Trial name
- 2-BRAINED (NCT06659809)
- Testing
- Tele-care video-feedback intervention (TVFI)
- Where
- 2 sites in Italy
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Literacy, Child Development
Rx for Success: RCT of an App for Dialogic Reading Training
The purpose of this randomized controlled trial is to explore the efficacy of amplifying dialogic reading training provided to families of infants and toddlers in the ROR program using a novel, smartphone-based application (Rx…
- Conditions
- Literacy, Child Development, Parenting
- Trial name
- NCT03828721
- Testing
- Rx for Success Smartphone Application, Control - screen time reduction
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Physical Activity, Adolescent
Development of The Pediatric Physical Activity Tracking Platform (Pedi@Ctivity) and Smartwatch-based Big Data Analysis
Regular physical activity is extremely important for the protection and development of physical and psychosocial health. In addition, acquiring regular physical activity habits in the early years of life allows maintaining…
- Conditions
- Physical Activity, Adolescent, Childhood Rheumatic Disease
- Trial name
- NCT05509907
- Testing
- Pedi@ctivity Analysis and Tracking Mobile Applications and Web Platform
- Where
- Turkey (Türkiye)
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Breast Neoplasms, Neoplasms by Site
Studying Normal Breast Tissue and Cancer Risk
Breast cancer is the most common cancer among women in the United States. Breast cancer research has been hampered by the difficulty in collecting normal breast tissue.
- Conditions
- Breast Neoplasms, Neoplasms by Site, Neoplasms, Breast Diseases
- Trial name
- NCT00341692
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Cancer Institute (NCI)
Autism, Autism Spectrum Disorder
Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism
The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young…
- Conditions
- Autism, Autism Spectrum Disorder, ASD
- Trial name
- PRT-HvC (NCT04899544)
- Testing
- Center-Based Pivotal Response Treatment (PRT) Intervention (PRT-C), Home-Based Pivotal Response Treatment (PRT Intervention (PRT-H)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Child Abuse, Child Neglect
Promoting Resilience and Lowering Risk in Early Childhood
An intervention study to provide in-the-moment parenting tips with the goal of increasing healthy parent-child interactions leading to resiliency in high-risk children.
- Conditions
- Child Abuse, Child Neglect, Parenting, Child Development
- Trial name
- NCT05479734
- Testing
- mHealth Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Oklahoma
Autism Spectrum Disorder
Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD
Autism spectrum disorder (ASD) consists of deficits in social, communication, and cognitive development, repetitive and stereotypic behaviors.
- Trial name
- NCT05439616
- Testing
- Cariprazine
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 161 people
- Sponsor
- AbbVie
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography, Machine Learning
- Trial name
- NCT05035511
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder, Autism
Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism
Autism spectrum disorder (ASD) is a very heterogeneous disorder with limited empirically validated behavioral and biological interventions.
- Trial name
- PRT-I (NCT03583684)
- Testing
- Pivotal Response Treatment Program (PRT-P)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
Memory
Longitudinal Investigation of Sleep, Memory, and Brain Development Across the Nap Transition
To examine the relations between sleep (nap transitions, sleep physiology), memory, and brain development longitudinally, the researchers will assess n=180 children (in order to acquire n=152 usable data sets) who are 36-54…
- Trial name
- HSR (NCT06351098)
- Testing
- nap
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Autism Spectrum Disorder, Autism
Music for Autism (M4A)
The Music for Autism (M4A) trial evaluates the neurobehavioral outcomes of a music therapy (MT) intervention, compared to a matched play therapy (PT) intervention, on social communication skills, brain connectivity and structural…
- Trial name
- M4A (NCT04936048)
- Testing
- Music Therapy, Play therapy
- Where
- 2 sites in Austria, Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- NORCE Norwegian Research Centre AS
Autism Spectrum Disorder, Parenting Stress
Feasibility and Acceptability of Laughter Yoga in Children With Autism Spectrum Disorder and Their Parents
This is a pilot randomised controlled trial to explore the acceptability and feasibility of laughter yoga about anxiety and depression reduction in children with ASD and parenting stress reduction for their parents.
- Conditions
- Autism Spectrum Disorder, Parenting Stress, Depression, Anxiety
- Trial name
- NCT06326255
- Testing
- laughter yoga
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- LAM Chung Yan Hemio
Autism Spectrum Disorder (ASD)
AB-2004 in Treatment of Irritability Associated With Autism Spectrum Disorder (ASD)
The purpose of this study is to establish the potential benefits, safety, and tolerability of AB-2004 in participants with irritability associated with autism spectrum disorder.
- Trial name
- NCT04895215
- Testing
- AB-2004
- Where
- 24 sites in United States, Australia and 1 more
- Volunteers
- 156 people
- Sponsor
- Vertero Therapeutics
Autism Spectrum Disorder
Augmented Reality for Behavior and Executive Function of Children With Autism Spectrum Disorder
The aim of the study is to determine the effects of usage of augmented reality for Restricted and repetitive behavior and executive function of children with autism spectrum disorder
- Trial name
- NCT05962047
- Testing
- Games of WonderTree Augmented Reality, Traditional therapy
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Williams Beuren Syndrome, Autism Spectrum Disorder
Molecular Characterization of Patients Affected by Williams Syndrome and Autism.
Williams Beuren syndrome (WBS) is a multiple malformations/intellectual disability (ID) syndrome caused by 7q11.23 microdeletion and clinically characterized by a typical neurocognitive profile including excessive talkativeness…
- Trial name
- WBA (NCT04095585)
- Testing
- chromosomal microarray analysis (CMA) and whole exome sequencing (WES)
- Volunteers
- 6 people
- Sponsor
- Hospices Civils de Lyon
Autistic Disorder, Autism
Randomized Controlled Trial of Acupuncture Versus Sham Acupuncture in Autistic Spectrum Disorder
We aim to study the efficacy of Acupuncture versus sham acupuncture in children with ASD.
- Trial name
- NCT00352248
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder
Mobile-based Games for Cognitive Training in Children With Neurodevelopmental Disorders
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with characteristic deficits in social functioning and presence of stereotypic behavior.
- Trial name
- NCT04308915
- Testing
- Game-based cognitive training
- Where
- India
- Volunteers
- 14 people
- Sponsor
- Indian Institute of Technology Kanpur
Pancreatic Exocrine Insufficiency
The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
- Trial name
- DETECTION (NCT05980221)
- Testing
- Metabolomics, 13C MTGT
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Food Hypersensitivity, Milk Hypersensitivity
Study of Milk Allergy and Tolerance in Children
The purpose of this study is to determine if children who are allergic to milk can increase tolerance through frequent dose-escalation every 6 months versus 12 months leading to eventual tolerance of less heated milk and…
- Trial name
- NCT00778258
- Testing
- Baked Milk, Non-baked Milk
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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