Clinical trials: Growth and Development
Autistic Disorder
Study of Acamprosate in Autism
Recent pharmacotherapy research in autism spectrum disorders (ASD) has successfully focused on treatment of co-occurring symptoms, including inattention, hyperactivity, and irritability that commonly occur in persons with ASD.
- Trial name
- NCT01813318
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autistic Disorder
Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology
During a previous therapeutic trial, investigators showed that the bumetanide improved significantly autism. This trial showed that a therapeutic response was obtained in 75% of cases.
- Trial name
- BUMAUTEP (NCT02947880)
- Testing
- Bumetanide
- Where
- France
- Sponsor
- University Hospital, Limoges
Autism Spectrum Disorder, Gastrointestinal Diseases
Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.
This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Diseases, Healthy
- Trial name
- NCT06290258
- Testing
- Fecal microbiota transplantation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Infant, Premature, Diseases
A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm Infants
Immature gastrointestinal functions increase the risk of poor growth as well as nosocomial infections and necrotizing enterocolitis (NEC) in the preterm infant.
- Trial name
- SBP (NCT02310425)
- Testing
- S. boulardii
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Lingfen Xu, MD
Triage
AI4Triage - Development of an Artificial Intelligence Based Methods for the Analysis of Triage Data.
Artificial intelligence, and in particular Graph Neural Networks (GNNs), have shown enormous potential in the analysis of complex clinical data.
- Trial name
- NCT07312968
- Testing
- Observation
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- University of Catanzaro
Child Development, Physical Disability
Children Participation Assessment Scale
Increasing the number of Turkish versions of questionnaires evaluating participation will increase the variety of assessment methods.
- Conditions
- Child Development, Physical Disability, Participation, Patient
- Trial name
- NCT05107518
- Testing
- Children Participation Assessment Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gazi University
Wheezing
Longitudinal Preschool Wheeze Biomarker Study
Preschool children (aged 1-5 years) account for 75% of all UK childhood wheezing hospitalisations. This has not changed over 20 years, meaning current treatments are not working and a new approach is needed.
- Trial name
- NCT06237660
- Testing
- Bronchoscopy, with bronchoalveolar lavage and endobronchial biopsy, Skin prick test, Finger prick blood test
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Imperial College London
Twin Brain Development
Early Brain Development in Twins
The purpose of this study is to study the role of genes and environment in early brain development using a twin approach. The investigators will use magnetic resonance imaging (MRI) to study brain structure and it's relationship…
- Trial name
- NCT01409746
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Allergy
The Prolonged Effect of Consumption of a Partially Hydrolyzed Infant Formula During the First 6 Months of Life on the Development of Allergic Manifestations At 5 Years of Age
The present study is a 5-year follow-up of the Allergy Reduction Trial (A.R.T.) birth cohort study of 551 infants at high-risk for allergy. The A.R.T.
- Trial name
- NCT05418491
- Testing
- No intervention is used in the current study. Interventions were given in the original A.R.T. study
- Where
- 3 sites in Bulgaria, Cyprus and 1 more
- Volunteers
- 455 people
- Sponsor
- FrieslandCampina
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT05664789
- Testing
- N acetyl cysteine
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Stanford University
ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Specific Phobia
Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders
The goal of this study is to develop a new internet-delivered cognitive behavioral therapy (ICBT) intervention for youths with anxiety disorders based on the best current knowledge about effective cognitive behavioral therapy for…
- Conditions
- ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Specific Phobia, Social Anxiety Disorder, Separation Anxiety Disorder
- Trial name
- NCT06661460
- Testing
- Internet-Delivered Cognitive Behavioral Therapy
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Lund University
Pain, Chronic, Pain, Chronic Post-Surgical
iCanCope With Post-Operative Pain (iCanCope PostOp)
There are few applications available in the community to help teenagers manage pain after surgery. The focus of this study is to better understand the pain experience of children after having surgery and to design a Smartphone…
- Trial name
- NCT05382962
- Testing
- iCanCope Post Op Application
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Autism Spectrum Disorder, Autistic Disorder
Sensorimotor Affect Relationship-based Therapy (SMART) for Children With Autism Spectrum Disorders Ages 2-12
The SMART Program at Nationwide Children's Hospital is an interdisciplinary social skills group that teaches children with autism spectrum disorders (ASD) ages 2-12 the fundamental social skills necessary to build and maintain…
- Trial name
- SMART (NCT01977248)
- Testing
- Sensorimotor Affect Relationship-based Therapy (SMART)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Nationwide Children's Hospital
Developmental Articulation Disorder, Stuttering
Study of Brain Activity During Speech Production and Speech Perception
The purpose of this study is to gain a better understanding of the brain's activity and organization in the development of speech disorders.
- Trial name
- NCT00004991
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism
Ziprasidone in Children With Autism: A Pilot Study
The purpose of this study is to see if the drug, ziprasidone, is effective in treating problems in adolescent associated with autism.
- Trial name
- NCT00208559
- Testing
- Ziprasidone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Drexel University College of Medicine
Bone Growth Abnormal, Inflammation
Effects of Increased Greek Yogurt Consumption in Youth and Young Adult Athletes
Physical activity and dairy consumption during growth and development are each known to improve peak bone mass in young adults. Peak bone mass, the maximum amount of bone a person will have in their lifetime, is typically reached…
- Trial name
- NCT05922462
- Testing
- Greek yogurt, Whey protein
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brock University
Posttraumatic Stress Disorder
Couple HOPES (Helping Overcome PTSD and Enhance Satisfaction)
Posttraumatic stress disorder (PTSD) is a common and disabling condition associated with intimate relationship problems and mental health problems in partners of those with PTSD.
- Trial name
- HOPES (NCT04231578)
- Testing
- Couple HOPES Guided, Internet-Delivered, Self-Help Intervention
- Where
- Canada
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Autism Spectrum Disorder, Conduct Disorder
Effectiveness of a Short Computer-based Emotion Recognition Training in Different Patient Groups
Emotion recognition and regulation are necessary skills for social interaction. Disrupted development of these processes severely interferes with socio-emotional development.
- Trial name
- NCT04845243
- Testing
- Emotionen Verstehen und Ausdrücken (E.V.A.)
- Volunteers
- 80 people
- Sponsor
- Prof. Christina Stadler
Refractive Errors
Effect of Colour Temperature of Reading Lamp on Refractive Error Development
This is a 12-month longitudinal randomized controlled trial aiming to evaluate the effect of colour temperature of reading lamp on refractive error development.
- Trial name
- NCT05733182
- Testing
- 3000K Reading lamp, 4500K Reading lamp, 6500K Reading lamp
- Where
- Hong Kong
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Parent-Child Relations, Child Development
FamilieTrivsel i Almen Praksis: a Mentalisation Programme for Families With Young Children
This cluster randomised trial aims to establish the effectiveness of an online intervention designed to improve the ability of parents to 'mentalise' - in other words to understand their own mental states and that of others…
- Conditions
- Parent-Child Relations, Child Development, Parenting
- Trial name
- NCT04129359
- Testing
- FamilieTrivsel, enhanced care as usual
- Where
- Denmark
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
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