Clinical trials: Gut Bacteria
Human Gut Microbiome Development
Phages Dynamics and Influences During Human Gut Microbiome Establishment
Microbial communities are key components of human environment. Consequently, human gut microbiome have been extensively studied providing a better understanding of the relations between bacterial populations and host physiology.
- Trial name
- METAKIDS (NCT03296631)
- Testing
- collection of diapers with fresh stools
- Where
- 2 sites in France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Obesity, Intestinal Bacteria Flora Disturbance
Study on Dietary Nutrition Intervention Techniques for Children Obesity
With the rapid development of society and economy, children's simple obesity is the rising in the world and has become a chronic disease which is one of the biggest public health challenges in the world.
- Conditions
- Obesity, Intestinal Bacteria Flora Disturbance, Body Weight
- Trial name
- NCT02539836
- Testing
- Dietary nutrition based on plant fermentation extract, MRI in quantifying liver fat with MRS
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Diarrhea
Etiology of Diarrhea in Guinea-Bissau and in Finland
Diarrhoea is the leading cause of death in the world with 2.2 million deaths every year. The majority of deaths are among children in developing countries, but the travellers encounter the disease as well.
- Trial name
- NCT01269554
- Where
- 3 sites in Finland, Guinea-Bissau
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Feeding; Disorder, Nonorganic Origin, Calcium Disorder
Evaluation of the Effect of Palm Olein Free Formula on Intestinal Flora and Gastrointestinal Tolerance
Depending on recent studies in literature the investigators aimed to compare whether gastrointestinal tolerance differs between infants fed with palm olein containing or palm olein free formulas.
- Conditions
- Feeding; Disorder, Nonorganic Origin, Calcium Disorder, Intestinal Bacteria Flora Disturbance
- Trial name
- NCT03770143
- Testing
- Feeding with palm olein formula
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Crohn Disease
Bacteria & Inflammation in the Gut (BIG) Study
Exclusive Enteral Nutrition (EEN) is the liquid diet given to children with active Crohn's Disease (CD). EEN has previously been shown to induce changes in major bacterial metabolites and dominant bacterial species which are more…
- Trial name
- BIG (NCT02341248)
- Testing
- Exclusive Enteral Nutrition (EEN)
- Where
- 5 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Acne Vulgaris
Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline.
- Trial name
- NCT07544251
- Testing
- Sarecycline, Doxycycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
MTBI - Mild Traumatic Brain Injury
Imaging of Injury Mechanism and Interaction of Intestinal Bacteria in Children With Mild Traumatic Brain Injury
Traumatic brain injury (TBI) is the leading cause of disability in children and young adults. Children with moderate to severe TBI are typically at risk of poor functional outcome in terms of neurocognitive impairment and…
- Trial name
- NCT05090007
- Testing
- magnetic resonance image, gut microbiota
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Healthy
Symbiotic & Colonization
The clinical trial aims at showing efficacy of prebiotics and the probiotic on microbiota balance. Together, the prebiotic solution in combination with the probiotic is expected to harmonize the microbiota of formula fed neonates…
- Trial name
- NCT01983072
- Testing
- Infant formula, Breastfeeding
- Where
- 4 sites in France, Poland
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Health, Children, Only
Characteristics of Intestinal Bacteria and Their Effects on Growth and Immune Function in Children at High Altitude
Microbes and the human body maintain a complex relationship of interaction and influence. Different regions, altitudes, and dietary habits have different degrees of influence on the composition of children's intestinal flora.
- Conditions
- Health, Children, Only, Gut Microbiota
- Trial name
- NCT06157346
- Where
- China
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Beneficial Bacteria in Gut
Color Synbiotics Study
This study is initiated to investigate the effect of infant formula with added specific synbiotics mixture on proportion of beneficial bacteria.
- Trial name
- NCT01813175
- Testing
- Regular non-hydrolysed cow's milk I, Regular non-hydrolysed cow's milk II, Regular non-hydrolysed cow's milk - control
- Where
- 3 sites in Thailand
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Bacteria Infection Mechanism
Study of Factors Influencing the Dynamics of Colonisation and Decolonisation of the Digestive Tract by Clostridioides Difficile in Infants
Clostridioides difficile (formerly C. difficile) is a bacterium found in the form of spores (a resistant form) to which patients may be exposed in a hospital environment.
- Trial name
- BBDIFF (NCT07512908)
- Testing
- cohort follow up
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondation Hôpital Saint-Joseph