Clinical trials: Gut Function
Congenital Heart Disease (CHD)
Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids
Butyric acid has been shown to promote gut health and improve the microbiome in multiple adult studies. In preliminary studies in older children with inflammatory bowel disease, butyric acid was shown to be safe.
- Trial name
- BASICS-Kids (NCT06882772)
- Testing
- 2 mL SunButyrate-TG, 4 mL SunButyrate-TG
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Nebraska
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Probiotics as Adjuvant Therapy in the Management of Irritable Bowel Syndrome
Studying the effects of adding probiotics to the drug regimen of patients with diarrhea predominant IBS
- Trial name
- NCT05523427
- Testing
- Two probiotic strains (L. plantarum and L. acidophilus)
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- University of Mosul
Abdominal Pain, Irritable Bowel Syndrome
Recurrent Abdominal Pain in Children
The purpose of this study is to: 1. To determine if fiber versus placebo improves symptoms in children with recurrent abdominal pain/irritable bowel syndrome. 2.
- Trial name
- NCT00526903
- Testing
- Elimination Diet
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Baylor College of Medicine
COVID-19-Associated Encephalitis, Long COVID
Longterm Influence of Pediatric Long COVID Syndrome
We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed.
- Trial name
- NCT05566392
- Testing
- Brain MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Crohn's Disease
A Long-term Active Treatment Study of Mongersen (GED-0301) in Subjects With Crohn's Disease
The purpose of this study is to assess long-term safety data of GED-0301 for a period of up to 208 weeks in adult subjects (i.e., ≥ 18 years of age) who participated in the core Phase 3 GED-0301-CD-002 and GED-0301-CD-003 studies…
- Trial name
- NCT02641392
- Testing
- GED-0301
- Where
- 231 sites in United States, Australia and 29 more
- Volunteers
- 310 people
- Sponsor
- Celgene
Fecal Incontinence, Constipation - Functional
Examination of a New Irrigation System for Transanal Irrigation in Children With Fecal Incontinence
The aim of this study is to investigate if a new irrigation system for transanal irrigation (TAI) is effective and more tolerable than the currently used system at the Pediatric Ward at Aarhus University Hospital.
- Trial name
- NCT05032534
- Testing
- Cone Small, Qufora A/S, Colotip, Coloplast A/S
- Where
- 2 sites in Denmark
- Volunteers
- 14 people
- Sponsor
- University of Aarhus
Functional Gastrointestinal Disorders (FGIDs), Weight Loss
Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates
Infants born by cesarean section commonly show early weight loss and slower recovery of birth weight, together with characteristic patterns of gut microbiota dysbiosis marked by reduced Bifidobacterium and Bacteroides and…
- Trial name
- NCT07320287
- Testing
- RO water, LiveSpo PREG-MOM, LiveSpo CONSY
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Hypnotherapy vs. Probiotics in Children With IBS and Functional Abdominal Pain
Current study aims to investigate the influence of gut-directed hypnotherapy and probiotic nutritional supplement (SymbioLact B) on gastrointestinal symptoms in children with functional abdominal pain or irritable bowel syndrome…
- Trial name
- NCT02613078
- Testing
- Gut-Directed Hypnotherapy, Nutritional Supplement, Self-Monitoring
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Obstructed Defecation Syndrome, Rectocele
Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM
The stapled transanal rectal resection (STARR procedure) is an effective treatment for obstructed defecation syndrome (ODS) caused by intussusception and rectocele.
- Conditions
- Obstructed Defecation Syndrome, Rectocele, Intussusception, SNS
- Trial name
- STARR (NCT00673400)
- Testing
- Stapled transanal rectum resection
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Cantonal Hospital of St. Gallen
Irritable Bowel Syndrome
Iyengar Yoga for Young People With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) affects as many as 14% of high school-aged students. Symptoms include discomfort in the abdomen, along with diarrhea and/or constipation and other gastroenterological symptoms, which can…
- Trial name
- NCT01107977
- Testing
- Iyengar yoga
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of California, Los Angeles
Irritable Bowel Syndrome
Saliva Testosterone Increases in Irritable Bowel Syndrome (IBS) Patients Beginning Choir Singing
The hypothesis was that a one-year experience of choir singing once a week is more beneficial than group discussions to saliva concentration of testosterone.
- Trial name
- NCT00931294
- Testing
- Choir singing, Information Group
- Where
- Sweden
- Volunteers
- 55 people
- Sponsor
- Stockholm University
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Motility Disorder of Small Intestine (Disorder)
Intestinal Dysmotility: Minute Rythm
Introduction: Intestinal manometry may detect phasic pressure patterns that suggest small bowel obstruction. The most common is the "clustered contractions pattern", characterized by repetitive short spouts of intestinal…
- Trial name
- NCT05230121
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Graft Vs Host Disease, Inflammatory Bowel Diseases
Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)
The goal of the Precision Diagnosis in Inflammatory Bowel Disease, Cellular Therapies, and Transplantation (PREDICT) trial is to apply a systems-biology approach to enable precision diagnostics for the key immunologic outcomes…
- Conditions
- Graft Vs Host Disease, Inflammatory Bowel Diseases, Functional Gastrointestinal Disorders
- Trial name
- PREDICT (NCT03369353)
- Where
- 4 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Boston Children's Hospital
Crohn's Disease
Acupuncture Treatment for Active Crohn's Disease
The purpose of this study is to observe the efficacy and safety of acupuncture and moxibustion for Crohn's disease and the regulation mechanism of intestinal microbiota and peripheral immunity.
- Trial name
- NCT02559037
- Testing
- Acupuncture and moxibustion
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Autism, Autism Spectrum Disorder
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Autism
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding autism.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Autism, Akinetic
- Trial name
- NCT04100863
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Crohn Disease, Inflammatory Bowel Diseases
Effect of Acupuncture on Patients With Crohn's Disease in Remission
To observe the therapeutic effect of acupuncture on Crohn's disease in remission and its influence of brain functional activity
- Trial name
- NCT04211129
- Testing
- acupuncture
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Endometriosis, Bowels Irritable
Impact of Dietary Guidance and Probiotics in the Treatment of Endometriosis and Irritable Bowel Syndrome in Women
Patients with endometriosis are 2 to 3 times more likely to develop Irritable Bowel Syndrome (IBS) than women without the condition.
- Trial name
- NCT07149519
- Testing
- probiotics - Lactobacillus spp
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- University of Sao Paulo
Crohn's Disease
Long-term Safety Study of Brodalumab in Adults With Crohn's Disease
The purpose of this study is to evaluate the safety and efficacy of long-term treatment with brodalumab in adults with Crohn's disease.
- Trial name
- NCT01199302
- Testing
- Brodalumab
- Where
- 34 sites in United States, Australia and 6 more
- Volunteers
- 67 people
- Sponsor
- Amgen
HIPEC, Gastro Intestinal Cancer
Effects of HIPEC on Postoperative Bowel Motility and Complications
This retrospective cohort study was conducted at our institution, involving patients with gastric cancer, appendiceal mucinous neoplasm, or colon cancer who underwent CRS with or without HIPEC between January 2017 and December…
- Conditions
- HIPEC, Gastro Intestinal Cancer, Adhesion Prevention, Bowel Functions
- Trial name
- NCT07353177
- Testing
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Where
- China
- Volunteers
- 193 people
- Sponsor
- Peking University People's Hospital