Clinical trials: Gynecologic Cancer
Stump
Deep Learning for Histopathological Classification and Prognostication of Gynaecologic Smooth Muscle Tumours
Smooth muscle tumors of the uterus that do not fit the diagnostic criteria of benignity (such as leiomyomas) or malignancy (such as leiomyosarcomas) are called STUMP (smooth muscle tumor of uncertain malignant potential).
- Trial name
- STUMP (NCT06540846)
- Testing
- No intervention
- Where
- France
- Volunteers
- 392 people
- Sponsor
- Institut Bergonié
Carcinomas, Amyloidosis
B-Receptor Signaling in Cardiomyopathy
We hope to determine the importance of different genes (including B receptors) in anthracycline-induced cardiomyopathy. This has important benefits to patients exposed to anthracyclines, as this could help determine whether…
- Conditions
- Carcinomas, Amyloidosis, Anal Cancer, Anemia
- Trial name
- NCT01135849
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Daniel Bernstein
Gynecologic Cancer
To Explore the Benefits of the MonaLisa Touch® System in Gynaecological Cancer Patients Treated by (Chemo)-RT
The increasing survival rate of gynaecological cancer patients highlights the need to improve their Quality of Life (QoL) after treatment.
- Trial name
- SQUAL (NCT05891470)
- Testing
- MonaLisa Touch device, Vaginal dilatators
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Jules Bordet Institute
Malignant Neoplasm of Cervix, Endometrium and Ovary
A Modified Approach for Morbid Obese With Gynecologic Cancer
Comparing standard midline approach with the modified approach in management of morbid obese patients with gynecologic cancers.
- Trial name
- NCT03096652
- Testing
- Approach for cancer resection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Gynecologic Cancer, Chemotherapy-induced Peripheral Neuropathy
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer
The aim of this study is to evaluate the effect of cryocompression therapy on the incidence and degree of taxane-induced peripheral neuropathy in gynecologic cancer patients receiving chemotherapy.
- Trial name
- NCT04563130
- Testing
- Cryocompression
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Duke University
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Radiation Therapy
Evaluation Conformal Radiotherapy for Gynecologic Cancer
The purpose of this study is comparision conformal radiotherapy for gynecologic cancer
- Trial name
- NCT00525538
- Testing
- conformal radiotherapy
- Where
- Turkey (Türkiye)
- Sponsor
- Istanbul University
Breast Cancer, Breast Neoplasm
Effects of Raloxifene on the Uterus and Ovaries of Premenopausal Patients
This research study is designed to work in cooperation with another study being conducted by the National Cancer Institute. The National Cancer Institute (NCI) is studying the effects of a drug called raloxifene on premenopausal…
- Trial name
- NCT00001837
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Gynecologic Cancer
Assessment of Sexual Dysfunction, Depression and Anxiety in Underserved, Minority Gynecologic Cancers Patients
Objectives: Assess the prevalence and severity of depression and anxiety in underserved and minority women seen in the gynecologic oncology clinic at Lyndon Baines Johnson General Hospital.
- Trial name
- NCT01031602
- Testing
- Surveys
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gynecologic Neoplasms, Venous Thromboembolism
Thromboprophylaxis After Surgery for Gynecologic Malignancy in China
Venous thromboembolism (VTE) is an important cause of post-operative morbidity and mortality in women undergoing surgery for gynecologic malignancies.
- Conditions
- Gynecologic Neoplasms, Venous Thromboembolism, Low Molecular Weight Heparin, Argatroban
- Trial name
- NCT02935530
- Testing
- s-LMWH, LMWH, Argatroban
- Where
- China
- Volunteers
- 315 people
- Sponsor
- Huazhong University of Science and Technology
Obstetric Complication, Gynecologic Cancer
Lung Ultrasound in Critically Ill Obstetrics and Gynecological Patients
Pulmonary dysfunction aggravates the illness of critically ill obstetrics and gynecological patients. Early identification with bedside technique and prompt management may improve the outcome of critical care in this vulnerable…
- Conditions
- Obstetric Complication, Gynecologic Cancer, Lung Diseases, Ultrasound
- Trial name
- POLUS (NCT06728709)
- Testing
- ultrasound detection of any abnormal ultrasonographical findings.
- Where
- Egypt
- Volunteers
- 280 people
- Sponsor
- Ain Shams University
Endometrial Cancer, Ovarian Cancer
Quality of Life in Survivors of Gynecologic Cancer
RATIONALE: Quality-of-life assessment in cancer survivors may help determine the long-term effects of having had gynecologic cancer and may help improve the quality of life for future cancer survivors.
- Trial name
- NCT00003795
- Testing
- quality-of-life assessment
- Where
- 44 sites in United States, Canada
- Volunteers
- 311 people
- Sponsor
- Gynecologic Oncology Group
Gynaecological Oncology
Survival Outcomes of Gynecologic Oncology Patients at Assiut University
This retrospective cohort study investigates survival outcomes of gynecological oncology patients treated at Assiut University Hospital between 2022 and 2025, comparing them to international benchmarks and assessing factors…
- Trial name
- NCT07232212
- Volunteers
- 200 people
- Sponsor
- Assiut University
Advanced Lung Carcinoma, Malignant Female Reproductive System Neoplasm
Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer
This trial will pilot a psychosocial intervention called Conquer Fear Support (CFS) in patients with stage III-IV lung or gynecologic cancer who are experiencing fear of cancer progression.
- Conditions
- Advanced Lung Carcinoma, Malignant Female Reproductive System Neoplasm, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8
- Trial name
- NCT03776253
- Testing
- Psychosocial Care Conquer Fear Support intervention (psychoeducation, attention training, worry management, and detached mindfulness components), Questionnaire Administration
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- City of Hope Medical Center
Education, Surgery
Video-based Coaching (VBC) in Gynecologic Surgery
This multi-centre, randomized controlled trial aims to assess the role of video-based coaching (VBC) in residency education in gynecologic and gynecologic oncology surgery.
- Conditions
- Education, Surgery, Gynecologic Cancer
- Trial name
- NCT05086783
- Testing
- Video-based coaching, Standard surgical teaching (master-apprentice model - (MAM))
- Where
- 3 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada