Clinical trials: HIV/STI Testing
Acquired Immunodeficiency Syndrome, HIV
Community Intervention for HIV Testing & Care Linkage Among Young MSM in Bulgaria
Young men who have sex with men (MSM) in low- and middle-income countries often do not seek out HIV testing, are unaware of their HIV-positive status, and do not receive early medical care, compromising their health and…
- Trial name
- NCT02639754
- Testing
- Social Network Leader Endorsement, HIV Counseling
- Where
- Bulgaria
- Volunteers
- 320 people
- Sponsor
- Medical College of Wisconsin
Hiv
Innovative Strategies to Increase ART Initiation and Viral Suppression Among HIV-positive Men in Malawi
Men in Sub-Saharan Africa are less likely to test for HIV, initiate ART, and more likely to initiate ART at later stages of disease.
- Trial name
- NCT04878601
- Testing
- Home-Based ART, Facility-Based ART
- Where
- Malawi
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV)
Combating Related Epidemics in HCV
This is a two-arm cluster randomized control trial to evaluate the effectiveness of a single-visit point-of-care (POC) test and treat bundle (intervention arm) compared to the current standard-of-care (SOC, control arm).
- Conditions
- HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV), HEPATITIS C (HCV)
- Trial name
- CREST (NCT07560046)
- Testing
- Cepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Hiv, Sexually Transmitted Diseases
Increasing HIV/STI Home Testing Via a Digital Intervention Among Black Women
The proposed intervention is a web-based intervention guided by theoretical components to increase HIV home testing among Black women at risk for HIV and sexually transmitted infections (STIs) in a HIV hotspot in the South.
- Conditions
- Hiv, Sexually Transmitted Diseases, Economic Problems
- Trial name
- NCT05390541
- Testing
- Empowered to Test Yourself, Educational Control
- Where
- 4 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV/AIDS, Sexually Transmitted Diseases
A Pilot Peer Mentor Intervention That Trains Black Men Who Have Sex With Men (BMSM) to Use and Promote Uptake of HIV/STI Self-Testing to Peers and Sex Partners: STAR Study (Self-Testing at Your Residence)
The objectives of the study are to assess the feasibility, reach and preliminary efficacy of a brief intervention that trains Black men who have sex with men [referred to as Index] (a) to use home-based testing for HIV and…
- Trial name
- STAR (NCT04121962)
- Testing
- Peer Mentor, Website only
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV/AIDS, HIV Infections
Enhancing Sexual Safety: Couples' Communication and HIV Testing Among YMSM
The purpose of this study is to compare different ways to deliver the couples HIV Testing and Counseling (CHTC) intervention that is suited for adolescents and young adults.
- Trial name
- WeTestATN156 (NCT04289116)
- Testing
- We Test, IHTC
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Florida State University
HIV Infections
Clinical Sensitivity of Clearview Rapid Tests in 12-17 y/o Pediatric Population
This study is to establish the clinical sensitivity of the Chembio Diagnostics Systems, Inc. Clearview COMPLETE HIV 1/2 Assay and Clearview HIV 1/2 Stat-Pak Assay (Clearview HIV tests) in pediatric subjects who are between 12 and…
- Trial name
- NCT00567749
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Chembio Diagnostic Systems, Inc.
HIV, AIDS
Testing a Secondary Prevention Intervention for HIV-Positive Black Young Men Who Have Sex With Men
The proposed research study aims to conduct a culturally-based secondary prevention intervention targeted toward HIV-positive Black young men who have sex with men (B-YMSM) to explore (1) feasibility and acceptability (Trial 1…
- Trial name
- NCT01751594
- Testing
- MOVE Intervention, H4L Comparison Intervention
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV, Syphilis
Evaluation of the MBio Combined Syphilis/HIV Point-of-Care Diagnostic Test
This is a diagnostic validation study for a combined Syphilis/HIV test made by MBio Diagnostics, Inc (MBio, Boulder, CO, USA). Although the MBio Syphilis/HIV diagnostic platform is designed for use at point of care (POC), it is…
- Trial name
- MBIO (NCT01530672)
- Testing
- MBIO POC combined HIV syphilis test ( SnapEsi)
- Where
- 2 sites in Kenya
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- PATH
Hiv
Engaging Men Through HIV Self-Testing With Differentiated Care to Improve ART Initiation and Viral Suppression Among Men in Malawi
Men in sub-Saharan Africa who test HIV-positive continue to have poor ART initiation and retention outcomes. The proposed project will test a home-based ART intervention for men who are living with HIV compared to facility-based…
- Trial name
- NCT04858243
- Testing
- Home-Based ART, Facility-Based ART
- Where
- Malawi
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV
Package of Care to Improve Retention in ART and Mortality Among Treatment Naive HIV Infected Individuals
This is a cluster randomized trial to determine whether a package of care including rapid antiretroviral therapy (ART) initiation, as compared to standard ART initiation, improves mortality, retention in care and viral…
- Trial name
- PRAN (NCT03723525)
- Testing
- Package of HIV care, Standard HIV care
- Where
- 10 sites in Nepal
- Volunteers
- 1,073 people
- Sponsor
- National Centre for AIDs and STD Control, Nepal
Hiv, Syphilis
Validation of Self Testing Using the INSTI Multiplex HIV1/2 Syphilis Antibody Test
This study aims to validate the percent agreement of the INSTI Multiplex Human Immunodeficiency (HIV) 1/2 syphilis antibody (Ab) test (INSTI POCT) when used as a self-test by patients compared to conventional serologic testing.
- Trial name
- NCT06953024
- Testing
- INSTI HIV/syphilis Point of Care Self-Test Administration
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
HIV Infections
Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand
This study will evaluate the effectiveness of a combination of clinic- and community-based voluntary counseling and testing programs in preventing HIV in African and Thai communities.
- Trial name
- NCT00203749
- Testing
- Community-Based HIV VCT, Standard clinic-based VCT
- Where
- 5 sites in South Africa, Tanzania and 2 more
- Volunteers
- 192,814 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Syphilis
Point of Care Tests for Syphilis and HIV
This study will evaluate the performance of two point-of-care dual syphilis and HIV tests [Multiplo TP/HIV test (MedMira Inc, Halifax, Nova Scotia) and the INSTI Multiplex HIV-1/HIV-2/Syphilis Antibody Test (bioLytical…
- Trial name
- PoSH (NCT04514848)
- Testing
- INSTI Multiplex HIV-1/2 Syphilis AB test, Multiplo Rapid TP/HIV test
- Where
- Canada
- Volunteers
- 1,526 people
- Sponsor
- University of Alberta
HIV/AIDS
HIV Awal (Early) Testing & Treatment Indonesia Project Intervention Phase
This study will be one of the first to systematically evaluate strategies to improve the implementation of a T\&T strategy in a concentrated epidemic in Asia.
- Trial name
- NCT03659253
- Testing
- Oral Fluid Based Self Testing, Simplified ART Initiation, CBO AND BROTHEL-BASED ART SERVICE
- Where
- 4 sites in Indonesia
- Volunteers
- 827 people
- Sponsor
- Gadjah Mada University
Human Immunodeficiency Virus
Testing Strategies for Couple Engagement in PMTCT and Family Health in Kenya
This study will test the efficacy and cost-effectiveness of an interdependence theory-based couples intervention in Kenya that reaches pregnant women and male partners through home visits by male-female pairs of lay health…
- Trial name
- Jamii Bora (NCT03547739)
- Testing
- Home visits, HIV Self-testing
- Where
- Kenya
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV Infections
Evaluation of Opt-Out Rapid HIV Testing in the Emergency Department
The purpose of this study is to evaluate the clinical effectiveness of performing opt-out rapid HIV screening in an urban, inner-city emergency department, as well as to evaluate its clinical efficiency, cost effectiveness, and…
- Trial name
- NCT00742898
- Testing
- Non-targeted opt-out rapid HIV screening
- Where
- United States
- Volunteers
- 120,000 people
- Sponsor
- Denver Health and Hospital Authority
AIDS/HIV PROBLEM
Rapid Oral Test for Therapeutic Response in HIV/AIDS Patients
This study has been designed to evaluate a new oral test for therapeutic monitoring of HIV/AIDS patients that are receiving the combination Anti-Retroviral Therapy (cART).
- Trial name
- NCT01507142
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Gaia Medical Institute
HIV (Human Immunodeficiency Virus), Chlamydia
Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland
The main goal of the observational study is to evaluate participants' satisfaction with free HIV and sexually transmitted infection (STI) testing and counselling offered by the cities of Lucerne and Zurich, Switzerland to young…
- Conditions
- HIV (Human Immunodeficiency Virus), Chlamydia, Gonorrhea, Syphilis
- Trial name
- feSTI (NCT07516912)
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pre-exposure Prophylaxis, HIV Infections
Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa
The goal of this trial is to understand which strategies work best to support pre-exposure prophylaxis (PrEP) use among female sex workers (FSW) and adolescent girls and youth women (AGYW) in uMgungundlovu, KwaZulu-Natal, South…
- Trial name
- NCT06274060
- Testing
- Case management, Food vouchers, PrEP support buddy
- Where
- South Africa
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health