Clinical trials: HIV Reservoir
HIV Infections
Safety and Effects of Using Prime-boost HIVIS DNA and MVA-CMDR Vaccine Regimens With or Without Toll-like Receptor 4 Agonist on HIV Reservoirs in Perinatally HIV Infected Children and Youth
Phase I, Proof of Concept, Open-Label, Randomized Clinical Trial to Evaluate the Safety and Effects of Using Prime-boost HIVIS DNA and MVA-CMDR Vaccine Regimens with or without Toll-like Receptor 4 Agonist on HIV Reservoirs in…
- Trial name
- HVRRICANE (NCT04301154)
- Testing
- HIVIS DNA/MVA-CMDR, HIVIS DNA + Cervarix and MVA-CMDR, Cervarix
- Where
- South Africa
- Volunteers
- 25 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
HIV Infection, Cancer
Treatment With Immunological Checkpoint Inhibitors of HIV-infected Subjects With Cancer
It has been reported that peripheral and lymph node resident Cluster of Differentiation 4 (CD4)+ T cells expressing Programmed cell death protein 1 (PD-1) contribute to Human Immunodeficiency Virus (HIV) persistence during…
- Trial name
- PembroHIV (NCT03767465)
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- IrsiCaixa
HIV, HIV Infections
The Tatelo Plus Study
The purpose of this study is to advance pediatric HIV treatment and cure research by evaluating the impact of a combination of three anti-HIV-1 broadly neutralizing antibodies (bNAbs) or analytic treatment interruption (ATI) on…
- Trial name
- NCT06508749
- Testing
- PGDM1400LS, VRC07-523LS, PGT121.414.LS
- Where
- 2 sites in Botswana
- Volunteers
- 41 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Characterization of HIV Reservoirs in Adolescents
Characterization of HIV-1 Reservoirs in HIV-1 Non-B Infected Adolescents on ART in Cameroon
Background: Combination antiretroviral therapy (cART) can bring HIV-1 in blood plasma to level undetectable by standard tests and allow a near-normal life expectancy for HIV-infected individuals.
- Trial name
- AVIR (NCT06363500)
- Testing
- non applicable
- Where
- Cameroon
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chantal Biya International Reference Centre for Research on Prevention and Management of HIV/AIDS
HIV-1-infection
IMPAACT 2015 - Evaluation of the HIV-1 Reservoir in the Central Nervous System of Perinatally-Infected Youth and Young Adults With Cognitive Impairment
IMPAACT 2015 is a cross-sectional, exploratory study that will investigate the central nervous system (CNS) reservoir in perinatally HIV-infected adolescents and young adults on effective antiretroviral therapy with…
- Trial name
- NCT03416790
- Where
- 12 sites in United States, Puerto Rico
- Volunteers
- 24 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group