Clinical trials: HIV Seronegativity
HIV Infections, Pregnancy
Active Immunization of HIV-1 Infected, Pregnant Women With CD4 Lymphocyte Counts >= 400/mm3: A Phase I Study of Safety and Immunogenicity of VaxSyn Recombinant gp160 (NOTE: Some Patients Receive Placebo)
To evaluate the safety of gp160 vaccine (VaxSyn) in HIV-1 infected pregnant women with CD4 counts >= 400 cells/mm3. To evaluate the immunogenicity of this vaccine in pregnant women and the passive acquisition of vaccine-specific…
- Conditions
- HIV Infections, Pregnancy, HIV Seronegativity
- Trial name
- NCT00000777
- Testing
- gp160 Vaccine (MicroGeneSys)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Preventing HIV/Aids in Drug Abusing Youth
This project involves two studies focusing on the engagement and treatment of adolescents diagnosed with substance use disorders.
- Trial name
- NCT00680719
- Testing
- IBFT /HIV prevention, IBFT
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
HIV Infections
Voluntary HIV Counseling, Testing, and Medication for Pregnant Women to Prevent Mother-to-Child HIV Transmission
Voluntary HIV counseling and testing (VCT) and anti-HIV drugs for pregnant women and their newborns decrease rates of mother-to-child transmission (MTCT) of HIV.
- Trial name
- NCT00084045
- Testing
- Intrapartum HIV counseling/testing, Postpartum HIV counseling/testing
- Where
- 2 sites in South Africa
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Evaluation of the Performance of Chembio Diagnostics Systems, Inc. DPP® HIV 1/2 Rapid Test
This study has been designed to evaluate the performance of the Chembio Diagnostics Systems, Inc. DPP® HIV 1/2 rapid test. The device is intended to qualitatively detect the presence of antibodies against HIV-1/2 in oral fluid…
- Trial name
- NCT01032902
- Testing
- In Vitro Diagnostic Device
- Where
- 5 sites in United States
- Volunteers
- 2,808 people, healthy volunteers welcome
- Sponsor
- Chembio Diagnostic Systems, Inc.
Healthy
HIV-1 Vaccine Test in Uninfected Adult Volunteers
This study will test the safety of an experimental vaccine against HIV and examine whether it induces an immune response to HIV. A vaccine is a substance given to try to create resistance or immunity to a disease or infection.
- Trial name
- NCT00045838
- Testing
- VCR-HIVDNA006-00-VP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Screening for the Presence of HIV-1, RNA and HBV DNA in Blood Donations
Evaluation of HIV-1, HCV and HBV Blood Screening Tests With Human Blood Donor Specimens
The purpose of this study is to validate the performance characteristics of an assay that tests for HIV-1, HCV and HBV on an automated blood bank instrument for registration submission.
- Trial name
- NCT00552214
- Testing
- Blood test
- Where
- Taiwan
- Volunteers
- 10,290 people, healthy volunteers welcome
- Sponsor
- Novartis
HIV, HIV Infections
Video-based Counseling & Rapid HIV Testing for Teens
This study evaluated the educational effectiveness of a youth-friendly pre-test video (derived from a previous qualitative study) and compared it with in-person HIV pre-test counseling.
- Trial name
- NCT00836550
- Testing
- Video, in-person HIV pre-test counseling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- North Bronx Healthcare Network
HIV, Sexually Transmitted Diseases
Safer Choices 2 - HIV, STD, & Pregnancy Prevention Program
The purpose of the study is to adapt, implement, and evaluate an effective theoretically-based, high school HIV prevention program,Safer Choices, for higher risk youth in alternative schools. Primary Research Question 1.
- Conditions
- HIV, Sexually Transmitted Diseases, Pregnancy, HIV Infections
- Trial name
- NCT00223314
- Testing
- HIV, STD, Pregnancy Prevention Curriculum
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- The University of Texas Health Science Center, Houston
HIV Infections, HIV Seronegativity
A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes
Genital herpes (HSV-2) is the most common cause of genital sores worldwide, and the presence of genital sores is a significant risk factor for becoming infected with HIV.
- Conditions
- HIV Infections, HIV Seronegativity, Herpes Genitalis
- Trial name
- NCT00076232
- Testing
- Acyclovir
- Where
- 3 sites in United States
- Volunteers
- 3,682 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Using Nevirapine to Prevent Mother-to-Child HIV Transmission During Breastfeeding
The many benefits of breastfeeding are well documented. However, because of the risk of mother-to-child transmission (MTCT) of HIV from an HIV infected mother to her infant, there is considerable concern over the practice…
- Trial name
- NCT00074412
- Testing
- Nevirapine
- Where
- 5 sites in South Africa, Tanzania and 2 more
- Volunteers
- 2,026 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Pregnancy
Active Immunization of HIV-Infected Pregnant Women: A Phase I Study of Safety and Immunogenicity of a rgp120/HIV-1 Vaccine (NOTE: Some Patients Receive Placebo)
PRIMARY: To evaluate the short-term safety of rgp120/HIV-1SF2 vaccine versus MF59 placebo administered to HIV-infected pregnant women.
- Conditions
- HIV Infections, Pregnancy, HIV Seronegativity
- Trial name
- NCT00001046
- Testing
- MF59, rgp120/HIV-1 SF-2
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, AIDS
Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission
The purposes of this study are to determine whether Carraguard® Gel can prevent the transmission of HIV when used during vaginal intercourse, and to confirm that the gel is safe for vaginal use.
- Conditions
- HIV Infections, AIDS, Sexually Transmitted Diseases, HIV Seroconversion
- Trial name
- NCT00213083
- Testing
- Carraguard (PC-515)
- Where
- 3 sites in South Africa
- Volunteers
- 6,203 people, healthy volunteers welcome
- Sponsor
- Population Council
Adolescent Behavior, Health Behavior
Peer Mentors for Adolescents in HIV Affected Families
This study will evaluate the effectiveness of a peer mentoring program designed for youths ages 9 to 15 whose parents or guardians are HIV infected.
- Conditions
- Adolescent Behavior, Health Behavior, HIV Seronegativity
- Trial name
- NCT00056953
- Testing
- Peer mentoring program
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infections
A Study of Zidovudine/Lamivudine and Either Nevirapine or Nelfinavir for Reduction of Mother-to-child HIV Transmission During Breastfeeding
The purpose of the study is to demonstrate that a regimen using highly active antiretroviral therapy (HAART) to maximally suppress maternal viral load in the late antenatal period and during the first six months of lactation is…
- Trial name
- KiBS (NCT00146380)
- Testing
- Zidovudine/Lamivudine and either Nevirapine or Nelfinavir, Breastfeeding for 6 months postpartum
- Where
- Kenya
- Volunteers
- 520 people
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections, Sexually Transmitted Diseases
Development and Evaluation of an HIV, STD, and Pregnancy Prevention Program for Middle School Students
This study will develop and evaluate a school-based HIV, STD, and pregnancy prevention program for 7th and 8th grade middle school students.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Pregnancy
- Trial name
- NCT00161382
- Testing
- HIV, STD, and pregnancy prevention curriculum, Standard sexual education curriculum
- Where
- United States
- Volunteers
- 3,007 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
HIV Infections, Pregnancy Related
HIV Testing Strategies in the Perinatal Setting
The purpose of the study is to determine whether an abbreviated pretest/post-test CDC recommended counseling is as equally acceptable to prenatal patients as the standard strategy using prenatal care nurses and medical providers…
- Trial name
- NCT00503308
- Testing
- Abbreviated HIV test counseling
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Infections, Sexually Transmitted Infections
HIV Prevention Program for African American Teen Males
The purpose of this study is to test if sexual health interventions can reduce the incidence of STIs among African American teens (15 to 21 years old).
- Trial name
- NCT00849823
- Testing
- Male Sexual Health Program, Focus on the Future Program
- Where
- United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
HIV Infections, HIV Seronegativity
Long-Term Effects of HIV Exposure and Infection in Children
As new drugs and vaccines are developed to prevent HIV disease progression and prolong survival of HIV infected patients, the short-term safety and effectiveness of these treatments are evaluated in research studies.
- Trial name
- NCT00006304
- Where
- 92 sites in United States, Puerto Rico
- Volunteers
- 4,150 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Reducing HIV Risks in African American Teens
This study is developing and testing an innovative, parent education intervention, Preparing Our Sons and Daughters for Healthy Futures.
- Trial name
- NCT00963963
- Testing
- Healthy Futures parent education
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Education Development Center, Inc.
HIV, HIV Infections
Evaluating Post-test HIV Counseling Videos for Teens
The design of this randomized controlled trial (RCT) is to test the effectiveness of a post-test behavioral video in educating adolescents about HIV transmission and affecting their intentions to engage in risk-reduction behavior.
- Trial name
- Control (NCT00851539)
- Testing
- Video
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- North Bronx Healthcare Network