Clinical trials: HIV Seronegativity
HIV Infections
Family-Based HIV Prevention for Latinos
The proposed project will develop and test an HIV prevention intervention for Latino families. This study will: 1. Conduct a pilot "run-through" of an adapted family-based intervention with three cohorts (about 24 families) to…
- Trial name
- NCT00582101
- Testing
- Family-Based HIV Prevention for Latinos, General Health Promotion
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV Infections
Evaluation of the Extension at Community Level of Safe Male Circumcision (ANRS 12126 ORANGE FARM 2)
This study is aimed at demonstrating whether or not Male Circumcision can be used as an effective public health prevention tool that will have an impact on HIV prevalence in the South African population.
- Trial name
- ORANGE FARM 2 (NCT00623051)
- Testing
- Male Circumcision
- Where
- South Africa
- Volunteers
- 27,000 people, healthy volunteers welcome
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
HIV Infections, Pregnancy
Maternal/Infant Peripartum NVP, Versus Infant Only Peripartum NVP, or Maternal LPV/r in Addition to Standard ZDV Prophylaxis for the Prevention of Perinatal (PMTCT) HIV in Thailand
The purpose of this study is to compare the efficacy of two doses of nevirapine (NVP) given only to the infants or lopinavir/ritonavir (LPV/r) from 28 weeks gestation with single dose (SD) NVP given to the mothers plus two doses…
- Trial name
- PHPT-5 (NCT00409591)
- Testing
- Maternal and infant nevirapine, Maternal lopinavir+ritonavir, zidovudine
- Where
- 43 sites in Thailand
- Volunteers
- 435 people
- Sponsor
- Institut de Recherche pour le Developpement
HIV Infections, HIV Seronegativity
A Phase I Study to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Antigen in Children Born to HIV-Infected Mothers
PRIMARY: To determine the safety of envelope recombinant proteins rgp120/HIV-1MN (Genentech) and rgp120/HIV-1SF2 (Chiron/Biocine) in infants who are of indeterminate HIV status born to HIV-infected women.
- Trial name
- NCT00000774
- Testing
- rgp120/HIV-1MN, rgp120/HIV-1 SF-2
- Where
- 37 sites in United States, Puerto Rico
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Nevirapine (NVP) Use to Prevent Mother-to-Child Transmission of HIV
HIV can be transmitted from an HIV infected mother to her infant through her breast milk. The purpose of this study is to determine whether giving infants of HIV infected mothers the anti-HIV drug nevirapine (NVP) for six weeks…
- Trial name
- NCT00074399
- Testing
- Nevirapine
- Where
- Ethiopia
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infection, Sexually Transmitted Diseases
Maintaining HIV Prevention Gains in Female Adolescents
In this study, an intervention is tested that is designed to reduced risky sexual behaviors in adolescent females. Study design: randomized, controlled study participants: 640 girls aged 15-19 years old length of follow-up: 1…
- Trial name
- NCT00161343
- Testing
- Health Improvement Project for Teens on HIV Prevention
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Rochester
HIV Infections
Therapeutic Schools: Affect Management and HIV Prevention
Adolescents are at risk for HIV because of sexual and drug behavior intiated during this developmental period. Those with psychological distress are less likely than their peers to benefit from frequently used skills-based…
- Trial name
- NCT00500487
- Testing
- Affect Management, HIV Prevention Skills, General Health Promotion
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV Infections, HIV Seronegativity
HIV Prevention Preparedness Study
The purpose of this study is to provide researchers with information that will help them prepare for a future study to test the efficacy of two anti-HIV vaginal gels.
- Trial name
- NCT00048282
- Where
- 10 sites in South Africa, Tanzania and 1 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Breastfeeding, Antiretroviral, and Nutrition Study
This is a comparative clinical trial among HIV-infected women and their infants to determine: 1. the benefit of nutritional supplementation given to women during breastfeeding 2.
- Trial name
- NCT00164736
- Testing
- Maternal zidovudine/lamivudine/lopinavir-ritonavir, Infant nevirapine, Maternal protein and calorie supplement
- Where
- Malawi
- Volunteers
- 2,369 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections
NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV Transmission
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are commonly included in anti-HIV drug regimens. However, HIV infected women who have previously taken the single dose NNRTI nevirapine (SD NVP) for the prevention of…
- Trial name
- OCTANE (NCT00089505)
- Testing
- Emtricitabine, Emtricitabine/Tenofovir disoproxil fumarate, Lopinavir/Ritonavir
- Where
- 11 sites in Botswana, Kenya and 5 more
- Volunteers
- 745 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV Infections, HIV Seronegativity
A Blood Test to Look at Cells of the Immune System in Healthy Children
The purpose of this study is to learn more about some of the immune cells in the blood (CD4 cells, for example) of healthy children in order to better understand the differences in the blood cells of children infected with HIV.
- Trial name
- NCT00001109
- Where
- 45 sites in United States, Puerto Rico
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Pregnancy
Nevirapine Plus Zidovudine to Prevent Perinatal HIV in Thailand
The purpose of this study was to assess the efficacy of a single dose of the drug nevirapine (NVP) given to pregnant women at onset of labor and to their infant 48-72 hours after birth in addition to standard oral zidovudine (ZDV…
- Trial name
- NCT00398684
- Testing
- Single dose nevirapine to the mother and to the child
- Where
- Thailand
- Volunteers
- 1,792 people
- Sponsor
- Institut de Recherche pour le Developpement
HIV Infections, Sexually Transmitted Diseases
Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community
This randomized controlled trial conducted in Rakai District, Uganda, has enrolled 997 HIV positive men and 500 men who declined to learn HIV results (regardless of HIV status).
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Papillomavirus Infections, Genital Herpes
- Trial name
- NCT00124878
- Testing
- Male circumcision
- Where
- Uganda
- Volunteers
- 5,200 people, healthy volunteers welcome
- Sponsor
- Wawer, Maria J., M.D.
HIV Infections, Hepatitis C
Behavioral Intervention for HIV and HCV-Uninfected Injection Drug Users
The purpose of this study is to test whether a six-session behavioral intervention for HIV and HCV seronegative injection drug users is effective in reducing sexual and injection risk behaviors that could lead to primary HIV and…
- Trial name
- NCT00164372
- Testing
- Peer Education Intervention
- Where
- 5 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections
HIV, Abuse, and Psychiatric Disorders Among Youth
One subgroup of adolescents at particular risk for HIV is those with psychiatric disorders. Furthermore, those with histories of sexual abuse have been found to have riskier attitudes, poorer sexual communication skills, and less…
- Trial name
- Project STAR (NCT00603369)
- Testing
- group intervention
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV, Empowerment
Empowerment Intervention for Young Women - Phase I
This study will begin to develop a culturally appropriate secondary prevention intervention for young HIV+ women through focus groups.
- Conditions
- HIV, Empowerment, HIV Infections
- Trial name
- NCT00891358
- Testing
- Prevention Empowerment Intervention for Young Women
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
HIV Prevention Within High-Risk Bulgarian and Hungarian Social Networks
This study will evaluate the effectiveness of peer-led HIV/sexually transmitted disease (STD)risk reduction educational counseling in reducing HIV risk behavior among the social networks of young men who have sex with men and…
- Trial name
- NCT00310973
- Testing
- Social Network Intervention
- Where
- 3 sites in Bulgaria, Hungary and 1 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
HIV Infections, Gonorrhea
Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection
The objective of the study is to determine the efficacy and safety of 0.5% and 2% PRO 2000/5 gels compared to placebo in preventing vaginally acquired HIV infection.
- Conditions
- HIV Infections, Gonorrhea, Chlamydial Infections, Genital Herpes
- Trial name
- NCT00262106
- Testing
- PRO 2000/5
- Where
- 6 sites in South Africa, Tanzania and 2 more
- Volunteers
- 9,404 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
HIV Infections, Herpesvirus 2, Human
Male Circumcision for HIV Prevention in Rakai, Uganda
Circumcision in HIV unifected men may reduce the likelihood of becoming infected with HIV, reduce sexually transmitted infections (STIs) in men, not engender increases in sexual risk behaviors, and be acceptable to men as a…
- Conditions
- HIV Infections, Herpesvirus 2, Human, Syphilis, Genital Diseases, Male
- Trial name
- NCT00425984
- Testing
- Adult male circumcision
- Where
- Uganda
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Scientific Evaluation of Peer Education and STD Treatment to Reduce the Spread of HIV in Zimbabwe
The purpose of this study is to determine whether community-based peer education and condom distribution combined with improved treatment of sexually transmitted infections are effective in reducing the spread of HIV infection in…
- Trial name
- NCT00390949
- Testing
- Peer education among commercial sex workers and clients, Condom distribution and promotion, Syndromic treatment of sexually transmitted infections
- Where
- Zimbabwe
- Volunteers
- 9,454 people, healthy volunteers welcome
- Sponsor
- Imperial College London