Clinical trials: HSIL
Cervical Intraepithelial Neoplasia, Squamous Intraepithelial Lesions of the Cervix
Conservative Management of HSIL in Patients With Future Pregnancy Aspiration
Conservative management of high-grade squamous intraepithelial lesions (HSILs) seems safe and justified in young women (<30 years), but evidence is insufficient on whether it is also advisable for older women.
- Conditions
- Cervical Intraepithelial Neoplasia, Squamous Intraepithelial Lesions of the Cervix, Uterine Cervical Dysplasia
- Trial name
- NCT04783805
- Testing
- Conservative management with regular follow-up, Conization
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
High-Grade Squamous Intraepithelial Lesions
Laser Ablation in the Treatment of High-grade Cervical Lesions
Cervical laser ablation is an effective, minimally invasive treatment with a low incidence of perinatal complications and minimal impact on fertility.
- Trial name
- NCT06333743
- Testing
- laser ablation, LEEP or Conization
- Volunteers
- 308 people
- Sponsor
- Peking Union Medical College Hospital
Cervical Intraepithelial Neoplasia, HPV Infection
Effect of HPV Integration on Prognosis of Young Women With CIN2 in China
Clinically, cervical precancerous lesion is one of the important diseases that endanger the life safety and fertility of young women.
- Conditions
- Cervical Intraepithelial Neoplasia, HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions
- Trial name
- NCT05282095
- Testing
- Follow up
- Where
- 20 sites in China
- Volunteers
- 300 people
- Sponsor
- Fujian Maternity and Child Health Hospital
HPV Infection, Virus Integration
Prognostic Study of HPV Virus Integration in Women With HSIL
Human papillomavirus (HPV) is currently one of the most common sexually transmitted infections, according to its carcinogenicity is divided into high-risk genotypes and low-risk genotypes, research has confirmed that carcinogenic…
- Conditions
- HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions
- Trial name
- NCT05745597
- Testing
- Follow up
- Where
- 13 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Fujian Maternity and Child Health Hospital
HPV Infection, LSIL, Low-Grade Squamous Intraepithelial Lesions
Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV Infection
Clinically, patients with persistent HR-HPV infection for more than 18 months or HR-HPV infection with CIN2 + need regular colposcopic biopsy to assess the outcome and progression of the disease.
- Conditions
- HPV Infection, LSIL, Low-Grade Squamous Intraepithelial Lesions, HSIL, High-Grade Squamous Intraepithelial Lesions, Virus Integration
- Trial name
- NCT05283239
- Testing
- Follow up
- Where
- 11 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Fujian Maternity and Child Health Hospital
High-Grade Squamous Intraepithelial Lesions
Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSIL
This study aimed to analyze perioperative information in patients with high-grade squamous intraepithelial lesion (HSIL) undergoing total hysterectomy (TH), offering insights into optimal surgery timing, selecting the operation…
- Trial name
- NCT06325592
- Testing
- surgical timing and operation path
- Where
- China
- Volunteers
- 826 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
AIN3, AIN2
ANAL PRECANCEROUS LESIONS IN HIGH-RISK PATIENTS.
HIV-positive patients, women with a history of genital neoplasia and patients under pharmacologically immunosuppression (e.g. transplanted recipients, Crohn´s disease and Lupus) are a high-risk population for anal…
- Conditions
- AIN3, AIN2, HSIL, High Grade Squamous Intraepithelial Lesions
- Trial name
- PACCO (NCT05060640)
- Testing
- Detection of anal HSIL in a routine colonoscopy.
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- University Fernando Pessoa
Human Papillomavirus
Human Papillomavirus in Menstrual Blood
The investigators tried to know whether a virus causing cervical cancer could be detected in menstrual blood and to set up a experimental setting to detect the virus.
- Trial name
- NCT01506128
- Testing
- Collecting a Pad used at the first menstrual period after enrollment
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Seoul National University Hospital
Cervical Intraepithelial Neoplasia, Papillomavirus Infections
Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL)
High-grade squamous intraepithelial lesions (HSIL), encompassing cervical intraepithelial neoplasia grade 2 (CIN2) with p16 positivity and grade 3 (CIN3), are precancerous conditions that require effective intervention.
- Trial name
- Aurora (NCT07669363)
- Testing
- Loop Electrosurgical Excision Procedure (LEEP) or Cold Knife Conization (CKC), HAL 5% with illumination
- Where
- 28 sites in China
- Volunteers
- 230 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University