Clinical trials: HTN
Diabetes (DM), Hypertension
Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF
This is an observational study aiming to characterize the pathophysiological features and clinical significance of cardiometabolic early-stage heart failure using advanced multimodal cardiovascular magnetic resonance (CMR)…
- Conditions
- Diabetes (DM), Hypertension, Heart Failure, Obesity & Overweight
- Trial name
- NCT07336316
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Systemic Lupus Erthematosus (SLE)
Team-based Implementation of Hypertension Management in Childhood Lupus
The goal of this study is to compare the effectiveness of widely used implementation strategies to promote adherence to guideline-concordant evidence-based practices for monitoring and controlling blood pressure in patients with…
- Trial name
- ABOUT TIME (NCT07792733)
- Testing
- Health Navigator Engagement, Team Charter with Performance Monitoring, Pre-visit worksheet
- Volunteers
- 1,200 people
- Sponsor
- Boston Children's Hospital
Hypertension
Reduce Medication Errors by Translating AESOP Model Into CPOE Systems
Medication errors are common, life-threatening, costly but preventable. Information technology and automated systems are highly efficient for preventing medication errors and therefore widely employed in hospital settings.
- Trial name
- AESOP (NCT03484793)
- Testing
- AESOP service system
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Taipei Medical University
Cardiovascular Diseases, Heart Diseases
Dietary Fiber and Cardiovascular Inflammatory Markers
To investigate the relationship between dietary fiber and cardiovascular inflammatory markers.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Non-insulin Dependent, Hypertension
- Trial name
- NCT00085800
- Sponsor
- Medical University of South Carolina
Preeclampsia, Severe Preeclampsia
Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women
The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe preeclampsia and healthy, pregnant individuals.
- Trial name
- NCT07265336
- Testing
- Arterial Blood gases
- Where
- Panama
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Thomas Hospital, Panama
Hypertension
307B - Safety, Tolerability and Pharmacokinetics Study of TOPROL-XL® in Hypertensive Pediatric Subjects
This was a 52-week, multicenter, open-label study to determine the safety, tolerability and pharmacokinetics of TOPROL-XL (metoprolol succinate) extended-release tablets (metoprolol CR/XL) in hypertensive pediatric subjects.
- Trial name
- NCT00255502
- Testing
- metoprolol succinate
- Where
- 31 sites in United States, Dominican Republic
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Glaucoma, Ocular Hypertension
Non-Interventional Study In Patients With Ocular Hypertension And Open Angle Glaucoma Treated With Xalatan And Xalacom
Non-interventional study to obtain real life data from the treatment with Xalatan and Xalacom in Germany and to assess the long-term efficacy and tolerability under routine conditions.
- Trial name
- XCHANGE (NCT01012245)
- Testing
- no intervention
- Volunteers
- 28,812 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Primary Aldosteronism
Optimizing Diagnosis Of Primary Aldosteronism
To optimize the confirmatory tests for primary aldosteronism.
- Trial name
- ODPA (NCT02755519)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chongqing Medical University
Hypertension
The Effect of Cocoa Flavonoids on Blood Pressure
The purpose of this study is to compare the effects on blood pressure of a daily intake of a flavonoid-rich cocoa drink with that of the same drink from which the flavonoids have been largely extracted.
- Trial name
- NCT00125866
- Testing
- Flavonoid rich or flavonoid depleted chocolate drink
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Imperial College London
COPD, Pulmonary Hypertension
Prevalence of Pulmonary Hypertension in COPD Patients
The prevalence of an increased pulmonary blood pressure amongst patients with chronic obstructive pulmonary disease (COPD)is unclear. So is the impact of abnormal pulmonary blood pressure on symptoms.
- Trial name
- NCT00614900
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- University of Aarhus
Focus of Study is on Dentist's Attitudes Toward BP Measures
Dental PROBE (Dental Practice suRvey of Office Blood Pressure mEasurement)
20% of Canadians are hypertensive with approximately 200,000 new cases each year. Early detection of hypertension affects outcomes, reducing the risk for heart attack, stroke, kidney disease, and dementia.
- Trial name
- Dental-PROBE (NCT01604200)
- Testing
- focus group
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
PreTerm Neonate, Pulmonary Hypertension of Newborn
Identification of the Risk of Remote Pulmonary Hypertension in Preterm Births.
This study aims to learn about the prevalence of pulmonary hypertension and right ventricular dysfunction in patients born prematurely, at birth and at a distance, and the association with the development of pulmonary…
- Conditions
- PreTerm Neonate, Pulmonary Hypertension of Newborn, Right Ventricular Dysfunction
- Trial name
- Iper-NeoRisk (NCT06800300)
- Where
- 2 sites in Italy
- Volunteers
- 51 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hypertension
Safety and Efficacy of Aliskiren in Pediatric Hypertensive Patients 6-17 Years of Age
This double-blind 8 week study will evaluate dose response, efficacy (blood pressure lowering effect) and safety of aliskiren in children 6 - 17 years old with hypertension at low, mid and high weight-based doses.
- Trial name
- NCT01150357
- Testing
- Aliskiren (6.25/12.5/25 mg), Aliskiren (37.5/75/150 mg), Aliskiren (150/300/600 mg)
- Where
- 48 sites in United States, Belgium and 7 more
- Volunteers
- 267 people
- Sponsor
- Novartis Pharmaceuticals
Portal Vein, Cavernous Transformation Of, Hypertension, Portal
Interventional Radiology for the Treatment of Symptomatic Portal Hypertension in Patients With Cavernous Transformation of Portal Vein
To evaluate the values of portosystemic shunt and other interventional radiology approaches for treatment of symptomatic portal hypertension in patients with cavernous transformation of portal vein.
- Trial name
- NCT02504034
- Testing
- Transhepatic portosystemic shunt, 6-French sheath, 22-gauge chiba needle
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sun Yat-sen University
Cardiovascular Diseases, Heart Diseases
Minneapolis Children's Blood Pressure Study
To examine environmental and familial correlates of childhood blood pressure in order to predict elevated blood pressure in young adulthood.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00005141
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hernia, Diaphragmatic, Hypertension, Pulmonary
Chronic Sildenafil for Severe Diaphragmatic Hernia
The purpose of this study is to test if sildenafil is effective in the treatment of infants with severe congenital diaphragmatic hernia (determined by the presence of prolonged pulmonary hypertension or prolonged oxygen…
- Conditions
- Hernia, Diaphragmatic, Hypertension, Pulmonary, Hypoplasia, Pulmonary
- Trial name
- NCT00133679
- Testing
- sildenafil
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
Glaucoma, Open-Angle
Micropulsed Laser Trabeculoplasty Using Different Parameters
This randomized, double blinded, clinical trial compares two different parameters setting of micropulsed laser trabeculoplasty for open angle glaucoma. Group one is treated with 1500 mW of Power, Group two with 1000 mW.
- Trial name
- NCT04900142
- Testing
- Micropulsed laser trabeculoplasty
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Modena and Reggio Emilia
Glaucoma
Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin C
A clinical trial to establish the long term response of using intraoperative 5-fluorouracil (5-FU) versus mitomycin C (MMC) in trabeculectomy glaucoma surgery.
- Trial name
- NCT00346489
- Testing
- 5-fluorouracil, Mitomycin C
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Indiana University
Hypertension, Pulmonary
An Observational Study For Ambrisentan
The purpose of the programme is to collect safety data on ambrisentan when used in clinical practice
- Trial name
- VOLT (NCT00679224)
- Testing
- ambrisentan
- Where
- 112 sites in Australia, Belgium and 13 more
- Volunteers
- 800 people
- Sponsor
- GlaxoSmithKline
Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
This study evaluates the effects of bosentan on oxygen saturation, hemodynamics and exercise capacity in patients with pulmonary arterial hypertension related to Eisenmenger physiology.
- Trial name
- NCT00317486
- Testing
- bosentan
- Volunteers
- 54 people
- Sponsor
- Actelion
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