Clinical trials: Hallucinations
Hallucinations, Psychoses
Treatment of Hallucinosis/Psychosis in Parkinson's Disease by an Investigational Drug
The primary objective is to demonstrate that the investigational new drug, ACP-103, is well tolerated by, and will not worsen parkinsonism in, patients with Parkinson's disease and psychosis.
- Conditions
- Hallucinations, Psychoses, Parkinson's Disease
- Trial name
- NCT00087542
- Testing
- ACP-103
- Where
- 13 sites in United States
- Volunteers
- 60 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Hallucinations, Schizophrenia
Multimodal MRI-guided rTMS to Treat Refractory Hallucinations
The efficacy of neuro-navigated rTMS for patients with schizophrenia suffering from drug-resistant multisensory hallucinations will be tested by the implementation of a double-blind randomized controlled trial (RCT) This study…
- Conditions
- Hallucinations, Schizophrenia, Perceptual Disorders
- Trial name
- MULTIMODHAL (NCT01373866)
- Testing
- MagPro X100 repetitive Transcranial Magnetic Stimulation
- Where
- 2 sites in France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Lille
Alzheimer's Disease, Psychosis
Treatment of Psychosis and Agitation in Alzheimer's Disease
Clinically, many patients with AD show no response or minimal response to antipsychotics for symptoms of agitation/aggression or psychosis, or they have intolerable side effects on these medications.
- Conditions
- Alzheimer's Disease, Psychosis, Agitation
- Trial name
- NCT02129348
- Testing
- Lithium
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- New York State Psychiatric Institute
Schizophrenia, Schizophreniform
Transcranial Direct Current Stimulation for Hallucinations in First-Episode Schizophrenia
The purpose of this study is to test the efficacy of transcranial direct current stimulation (tDCS) for the treatment of auditory hallucinations in patients currently on risperidone treatment who are experiencing recent onset…
- Conditions
- Schizophrenia, Schizophreniform, Schizoaffective Disorder, Psychosis Not Otherwise Specified (NOS)
- Trial name
- NCT02661347
- Testing
- Risperidone, tDCS
- Where
- United States
- Sponsor
- Northwell Health
Parkinson's Disease Psychosis, Dementia With Lewy Bodies
Comparing Antipsychotic Medications in LBD Over Time
The primary objective of this study is to determine whether treatment with pimavanserin or quetiapine is associated with a greater improvement in psychosis when used in a routine clinical setting to treat hallucinations and/or…
- Trial name
- CAMELOT (NCT05590637)
- Testing
- Pimavanserin, Quetiapine
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Auditory Hallucination, Hearing Voices When No One is Talking
Imagery Interventions for Auditory Vocal Hallucinations
This study explores the feasibility, acceptability, and effectiveness of four imagery intervention techniques (metacognitive imagery intervention, imagery rescripting, promoting positive imagery and competing imagery task) for…
- Conditions
- Auditory Hallucination, Hearing Voices When No One is Talking, Psychosis
- Trial name
- NCT05603260
- Testing
- Imagery intervention for voice hearing (meta-cognitive imagery rescripting), Imagery intervention for voice hearing (Imagery rescripting), Imagery intervention for voice hearing (promoting positive imagery de novo)
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Hella Janssen
Auditory Hallucinations in Patients With Schizophrenic Disorders
High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Schizophrenia : a Randomized Controlled Study
Background: Repetitive transcranial magnetic stimulation (rTMS) is a recent therapeutic which has demonstrated its efficacy in the treatment of auditory hallucinations in patients with schizophrenic disorders.
- Trial name
- TMS-Hz (NCT01022489)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Auditory Hallucinations
The Physalis Child : Identification of Cognitive and Emotional Factors
The aim of this study is to show presence of cognitive and emotional factors on the beginning and persistence of auditory hallucinations in non-psychotic children.
- Trial name
- NCT02567500
- Testing
- Patients with auditory hallucination, Patients without auditory hallucination
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fondation Lenval
Schizophrenia
rTMS for Auditory Hallucinations Guided by Magnetoencephalography
rTMS and MEG for auditory hallucinations via self controlled clinical trials. Repetitive transcranial magnetic stimulation (rTMS) can increase or decrease cortical excitability in patients with psychosis (such as schizophrenia).
- Trial name
- NCT05598450
- Testing
- rTMS and MEG for auditory hallucinations via self controlled clinical trials
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Psychosis, Schizophrenia
ReMindCare App for Patients From First Episode of Psychosis Unit.
ReMindCare is an app designed by the Unit of Psychiatry at the Clinical Hospital of Valencia in liaison with the Polytechnic University of Valencia.
- Conditions
- Psychosis, Schizophrenia, Psychotic Disorders, Delirium
- Trial name
- NCT03807388
- Testing
- ReMindCare Intervention Group, Treatment as Usual
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Instituto de Investigacion Sanitaria INCLIVA
Alzheimer's Disease
CATIE-Alzheimer's Disease Trial
The CATIE Alzheimer's Disease Trial is part of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Project. The study is for people with Alzheimer's disease who are having trouble with their thinking or…
- Trial name
- NCT00015548
- Testing
- Olanzapine, Quetiapine, Risperidone
- Where
- 34 sites in United States
- Volunteers
- 450 people
- Sponsor
- National Institute of Mental Health (NIMH)
Hallucinations, Verbal Auditory
Virtual Reality Therapy for Voice Hearing (VR-VOICES): a Randomized Controlled Trial
Rationale: Auditory verbal hallucinations (AVH) - hearing voices that others cannot hear - are common in mental illnesses. For many people AVH are distressing, disabling and persistent, despite medication.
- Trial name
- VR-VOICES (NCT06013748)
- Testing
- VR-VOICES, Treatment as usual
- Where
- 3 sites in Netherlands
- Volunteers
- 112 people
- Sponsor
- University Medical Center Groningen
Auditory Hallucinations, Schizophrenia Spectrum
Cost-utility Study of Cognitive-behavioral Management of Auditory Hallucinations in Schizophrenic Disorder
The aim of the study is to assess the effectiveness and costs of a cognitive-behavioral treatment (CBT) for auditory hallucinations (psychotherapy) as an adjunct to usual care, comparing it to the effectiveness and costs of usual…
- Trial name
- VOICES (NCT07134816)
- Testing
- Cognitive and behavioral therapy for auditory hallucinations, Usual treatment
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia, Psychological Trauma
Cognitive Behaviour Therapy for Voices and Dissociation
Case series design with participants with psychosis with a history of interpersonal trauma/abuse and current distressing auditory verbal hallucinations and dissociative experience.
- Conditions
- Schizophrenia, Psychological Trauma, Dissociation, Hallucinations
- Trial name
- NCT04990414
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 19 people
- Sponsor
- Greater Manchester Mental Health NHS Foundation Trust
Schizophrenia, Hallucinations
Changes in Auditory Verbal Hallucination During Atypical Antipsychotic Treatment of Patients With Schizophrenia
The purpose of this study is to evaluate the changes in various aspects of auditory verbal hallucinations during 24-week antipsychotic treatment in naturalistic condition.
- Trial name
- NCT00328952
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Medical Education, Generative Artificial Intelligence
Teaching Medical Students to Verify AI-Generated Citation Hallucinations
Generative artificial intelligence (GenAI) tools are increasingly used by medical students for literature searching, scientific writing, and research. However, AI-generated citations may contain errors.
- Trial name
- SARA (NCT07844746)
- Testing
- SARA Citation-Verification Training, Responsible GenAI Education Intervention Description
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam Medical College
Parkinson Disease
Donepezil to Treat Dementia in Parkinson's Disease
This study will evaluate the safety and effectiveness of donepezil (Aricept) for treating mild dementia in patients with Parkinson's disease.
- Trial name
- NCT00030979
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alzheimer's Disease, Dementia
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Patients With Hallucinations and Delusions Associated With Alzheimer's Disease
The purpose of this study is to assess the effectiveness and safety of risperidone (an antipsychotic medication) versus placebo for the treatment of patients with hallucinations and delusions associated with Alzheimer's disease.
- Trial name
- NCT00287742
- Testing
- risperidone
- Volunteers
- 33 people
- Sponsor
- Janssen Pharmaceutical K.K.
Psychosis
Psychosis Associated With Methylphenidate in Children and Adolescents
perform a study in VigiBase® to assess if methylphenidate was associated with an over-reporting of psychosis including hallucinations in children and adolescents and to characterize those psychosis.
- Trial name
- NCT06518330
- Testing
- Intake of Methylphenidate
- Where
- France
- Volunteers
- 46,233 people
- Sponsor
- University Hospital, Caen
Dissociation, Auditory Hallucination
Psychological Therapy for Dissociation, Trauma and Voices: A Single Case Experimental Design
Connection to Environment with Cognitive Therapy (CONNECT): A Single-Case Experimental Design Exploring Dissociative Experiences and Voices Emerging empirical evidence has suggested that dissociation is a robust determinant of…
- Conditions
- Dissociation, Auditory Hallucination, Trauma, Psychological, Psychosis
- Trial name
- CONNECT (NCT04127526)
- Testing
- Connection to Environment with Cognitive Therapy (CONNECT)
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde