Clinical trials: Head Pain
Headache, Headache Disorders
Mind Body Balance for Pediatric Migraine
This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT04715685
- Testing
- 40 minute session, 20 minute session, home practice e-health
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Brain Concussion, Neck Pain
Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain
Assess the feasibility of recruiting, enrolling and randomizing patients with concussion symptoms and neck pain to receive manual therapy and cervical rehabilitative exercises in addition to standard concussion treatment.
- Trial name
- ConCerv (NCT06616272)
- Testing
- Cervical rehabilitation, Standard Concussion Care
- Where
- 4 sites in United States, Ireland and 1 more
- Volunteers
- 2 people
- Sponsor
- University of Pittsburgh
Migraine
A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine
The main goal of the study is to assess the long-term safety of eptinezumab on children and adolescents ages 6 to 17 with chronic or episodic migraine.
- Trial name
- REJOIN (NCT05164172)
- Testing
- Eptinezumab
- Where
- 64 sites in United States, Argentina and 9 more
- Volunteers
- 600 people
- Sponsor
- H. Lundbeck A/S
Headache, Migraine, Migraine
Mind and Body Approaches to Pain Reduction in Youth With Migraine
The overarching objective of this protocol is to identify and understand the neural and pain processing mechanisms by which youth with migraine improve in response to preventive treatment.
- Conditions
- Headache, Migraine, Migraine, Migraine Disorders, Headache
- Trial name
- NCT03472092
- Testing
- Cognitive Behavioral Therapy (CBT), Amitriptyline, Biofeedback-Assisted Relaxation Training (BART)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Migraine
CHOCOlate MeLatonin for AdolescenT MigrainE
Existing treatments for acute migraine are not effective for all children and adolescents, and can cause side effects. Investigator propose a dose-finding study of melatonin for acute migraine treatment in children and…
- Trial name
- CHOCOLATE (NCT03597529)
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Amy Gelfand
Migraine, Headache
The Role of CGRPand Nociceptin in Migraine
The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was…
- Trial name
- NCT00155129
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pain, Postoperative
Effect of Auditory Distractions on Pediatric Postoperative Pain
The aim of the study was to determine the effect of different auditorial methods of attention distraction on postoperative pain and anxiety in children.
- Trial name
- NCT03704961
- Testing
- music and audiobook listening
- Volunteers
- 3 people
- Sponsor
- Uludag University
Familial Hemiplegic Migraine, Migraine With Aura
Calcitonin Gene-related Peptide in Familial Hemiplegic Migraine (FHM) and Migraine With Aura (MA)
The aim of the present study is to explore the importance of migraine phenotype on the headache/migraine responses after CGRP in FHM-patients, MA-patients and healthy volunteers.
- Conditions
- Familial Hemiplegic Migraine, Migraine With Aura, Healthy
- Trial name
- CGRP-2008 (NCT00687947)
- Testing
- CGRP
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine in Adolescence, Headache
A Wearable Nerve Stimulator for Chronic Migraine/Headache and Mood Disturbance in Adolescents
The aim of this clinical trial is to test a wrist-worn nerve stimulator in adolescents with chronic migraine/headache and mood disturbance.
- Conditions
- Migraine in Adolescence, Headache, Mood Disturbance
- Trial name
- NCT05702528
- Testing
- Apollo Neuro
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of South Carolina
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Pain, Postoperative, Post-Craniotomy Headache
Scalp Infiltration With Methylprednisolone Plus Ropivacaine for Post-Craniotomy Pain in Children
At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the…
- Trial name
- NCT03636165
- Testing
- Methylprednisolone, Ropivacaine
- Volunteers
- 90 people
- Sponsor
- Beijing Tiantan Hospital
Elbow Pain, Supracondylar Humerus Fracture
The Utilization of Ultrasound to Diagnose Pediatric Elbow Fractures
The goal of this intervention trial is to learn if a ultrasound diagnosis of elbow fractures can improve care in pediatric patients seen in the emergency room.
- Conditions
- Elbow Pain, Supracondylar Humerus Fracture, Radial Head Fractures, Radial Head or Neck Fractures
- Trial name
- NCT07212036
- Testing
- Ultrasound of the elbow, X-ray of elbow
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Migraine
Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine
This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with episodic migraine.
- Trial name
- OASIS(EM) (NCT03836040)
- Testing
- Erenumab Dose 1, Erenumab Dose 2, Erenumab Dose 3
- Where
- 11 sites in United States, Belgium and 2 more
- Volunteers
- 457 people
- Sponsor
- Amgen