Clinical trials: Healthy Control
Meningococcal Vaccine
MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age
The aim of this study is to determine the immunologic noninferiority of MenABCWY to licensed vaccines Trumenba and MenACWY-CRM (Menveo) by assessing the safety and immunogenicity of MenABCWY and the comparators in both ACWY-naïve…
- Trial name
- NCT04440163
- Testing
- MenABCWY, Saline, Trumenba
- Where
- 78 sites in United States, Czechia and 3 more
- Volunteers
- 2,431 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cardiovascular Care, Cardiovascular Diseases Health Behavior
Healthy Heart, Healthy Life" Program on Cardiovascular Health Behaviors
This study evaluated the effect of the "Healthy Heart, Healthy Life" education program on the cardiovascular health behaviors of middle school students.
- Trial name
- NCT07781280
- Testing
- EDUCATION
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Healthy Adolescents
Extended Reality Cognitive and Breathing Training With Eye Tracking for Attention and Stress Regulation in Adolescent Basketball Players
This study examines whether virtual reality (VR) technology can serve as a supplementary training tool for adolescent basketball players.
- Trial name
- XR-CogBreathe (NCT07869446)
- Testing
- Cognitive XR, Breathing XR
- Where
- 2 sites in Latvia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Antenatal Care
Group Antenatal Care and Delivery Project
Antenatal care (ANC) has the potential to play a pivotal role in ensuring positive pregnancy outcomes for both mothers and their newborns.
- Trial name
- GRAND (NCT04033003)
- Testing
- Group ANC
- Where
- 14 sites in Ghana
- Volunteers
- 1,761 people
- Sponsor
- University of Michigan
Vaccines, Pneumococcal
Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants
The purpose of this study is to assess the safety, tolerability and immunogenicity of a 13-valent pneumococcal conjugate (13vPnC) vaccine compared to Prevenar (7vPnC), when given concomitantly with routine pediatric vaccines in…
- Trial name
- NCT00366678
- Testing
- 13-valent pneumococcal conjugate vaccine, 7-valent pneumococcal conjugate vaccine, Pentavac
- Where
- 45 sites in France
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Infant Sleep and Crying
Effects of Two Swaddling Techniques on Infant Sleep, Crying, and Maternal Comfort
The goal of this clinical trial is to learn how two different safe swaddling techniques affect sleep duration, crying duration, and maternal comfort in infants aged 1-4 months and their mothers.
- Trial name
- NCT07868380
- Testing
- Hip-Healthy Swaddling, Midline Flexion Swaddling
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Izmir University of Economics
Meningococcal Vaccine
A Trial to Describe the Immunogenicity and Safety of 2 Doses of Bivalent rLP2086 (Trumenba) and a Pentavalent Meningococcal Vaccine in Healthy Subjects >=10 to <26 Years of Age.
This study is examining safety and immunogenicity of 2 doses of Trumenba administered on a 0-,6- month schedule. This trial is also studying safety and immunogenicity of a meningococcal pentavalent vaccine.
- Trial name
- NCT03135834
- Testing
- MenABCWY, Saline, rLP2086
- Where
- 75 sites in United States, Czechia and 2 more
- Volunteers
- 1,610 people, healthy volunteers welcome
- Sponsor
- Pfizer
Lyme Disease
Safety Study of a Vaccine to Help Protect Against Lyme Disease in Healthy Children
This study is to understand if the study vaccine (called VLA15) is safe in healthy children. We are looking for children who: are healthy are age 5 through 17 have not been diagnosed with any form of Lyme disease in the past have…
- Trial name
- NCT05634811
- Testing
- VLA15, Normal Saline
- Where
- 65 sites in United States
- Volunteers
- 3,547 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Phase I Clinical Trial With Whole Virus Inactivated Influenza H5N1 Vaccine in Healthy Adolescents and Adults
Influenza is an acute respiratory infection caused by influenza virus with high incidence and serious complications even causing death.
- Trial name
- NCT01676675
- Testing
- 7.5μg /0.5ml, 15.0μg /0.5ml, 30.0μg /0.5ml
- Where
- China
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Varicella
Safety and Immunogenicity of Live Attenuated Varicella Vaccine in Healthy Population Aged ≥13 Years Old
This is a randomized, blind, controlled clinical trial of live attenuated varicella vaccines manufactured by Shanghai Institute of Biological Products Co.,Ltd.
- Trial name
- NCT05158777
- Testing
- Live attenuated varicella vaccines manufactured by Shanghai Institute of Biological Products Co.,Ltd., Live attenuated varicella vaccines manufactured by Changchun BCHT Biotechnology Co.,Ltd
- Where
- China
- Volunteers
- 2,480 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute Of Biological Products
Healthy, Posttraumatic Stress Disorder
Brain Function in Mentally Ill Adolescents
The purpose of this study is to use brain imaging technology to examine the brain activity of adolescents with post-traumatic stress disorder (PTSD) and/or major depressive disorder (MDD) before and after treatment.
- Conditions
- Healthy, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT00025857
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- National Institute of Mental Health (NIMH)
Respiratory Syncytial Virus Infections
A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY)
The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy late preterm and term infants who are 35 weeks or greater gestational age and…
- Trial name
- MELODY (NCT03979313)
- Testing
- MEDI8897
- Where
- 198 sites in United States, Argentina and 29 more
- Volunteers
- 3,012 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Bordetella Pertussis, Whooping Cough
Immunogenicity and Safety of BPZE1 Intranasal Pertussis Vaccine in Healthy School-age Children
This study evaluates the safety and immunogenicity of the BPZE1 live, attenuated pertussis vaccine, intended to prevent nasopharyngeal colonization and pertussis disease, and compares BPZE1 vaccine vs Boostrix vaccine vs both…
- Trial name
- NCT05116241
- Testing
- BPZE1 pertussis vaccine and Boostrix
- Where
- 16 sites in Australia, Costa Rica and 1 more
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- ILiAD Biotechnologies
Obesity
Promoting Overweight Adolescents Physical Activity
Objectives: Aim of this study is to evaluate the effectiveness of Facebook-delivered lifestyle counseling intervention on overweight and obese adolescent's physical activity, BMI and adherence to healthy lifestyles.
- Trial name
- NCT02295761
- Testing
- Lifestyle counseling (Fb), Lifestyle counseling + activity monitor (Fb+Act)
- Where
- Finland
- Volunteers
- 46 people
- Sponsor
- Heidi Ruotsalainen
Induction of General Anesthesia
Propofol Versus Sevoflurane for Induction of GA in Infants
This comparative study aims to investigate the haemodynamic safety profile for induction of general anesthesia in infants 3 months or less guided by electrical cardiometry parameters versus sevoflurane.
- Trial name
- NCT05105022
- Testing
- Propofol
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Temporomandibular Disorder (TMD), Chronic Pain
Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders and Healthy Controls
Occlusal sensitivity refers to the ability to detect fine objects placed between opposing teeth during biting or in maximum intercuspation.
- Trial name
- SENFOIL (NCT07163494)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Typhoid
Immune Non-inferiority and Safety of a Vi-DT Typhoid Conjugate Vaccine
This is a Multicenter, observer-blinded, randomized, Active controlled, Phase 3 study in healthy 6 months to 45 years aged Nepalese at the time of the first vaccine dose. The study objectives are: I.
- Trial name
- NCT03933098
- Testing
- Test Vaccine Vi-DT Typhoid conjugate, Control Vaccine Typbar TCV®
- Where
- 4 sites in Nepal
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute