Clinical trials: Hearing Disorders
Children, Only, Vestibular Disorder
Vestibular and Postural Function in an Unselected Group of Children With Sensorineural Hearing Loss
The goal of this prospective cohort study is to investigate the vestibular function in children with unilateral or bilateral sensorineural hearing loss.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function, Sensorineural Hearing Loss
- Trial name
- VASIC (NCT06229717)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Gødstrup Hospital
Chronic Subjective Tinnitus
Trial of Management of Chronic Tinnitus by Sound Therapy and Cognitive Behavioral Therapy
clinical trial: The main aim of this study is to compare the effectiveness of Cognitive Behavioral Therapy (CBT) and Sound Therapy, both individually and in combination, in the management of patients with chronic subjective…
- Trial name
- NCT07665385
- Testing
- Group A: sound therapy, Group B: Cognitive Behavioral Therapy, Group C: Combined CBT + Sound Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Congenital Hypothyroidism, Hearing Loss
The Prevalence of Hearing Loss Among Children With Congenital Hypothyroidism
Congenital hypothyroidism (CH) occurs in 1:4000 live births. Neurological disturbances like speech delay, motor delay and lower IQ were reported in children with CH.
- Trial name
- NCT01223638
- Testing
- Audiometry
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Hearing Loss
N6 Input Processing in Traditional CI Recipients
The purpose of this study is to evaluate the enhanced signal processing features of the Nucleus 6 Sound Processor on existing Nucleus cochlear implant recipients currently using the Nucleus 5 Sound Processor.
- Trial name
- NCT02239263
- Testing
- Nucleus 6 Sound Processor
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cochlear
Hearing Loss
Body Mass Index and Audiology Function
Obesity may directly or indirectly lead to hearing loss
- Trial name
- NCT03172663
- Testing
- pure tone audiometry
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hearing Loss
The Hearing Aid Effectiveness After Aural Rehabilitation (HEAR) Trial
This study compares the effectiveness of hearing aid appointments provided in a group format to those provided in an individual format.
- Trial name
- NCT00260663
- Testing
- Group hearing aid fittings, Group hearing aid follow-up
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- US Department of Veterans Affairs
Enlarged Vestibular Aqueduct, Sensorineural Hearing Loss
Enlarged Vestibular Aqueduct Registry
People with the congenital anatomical malformation known as "Enlarged Vestibular Aqueduct" (EVA) may experience decline in hearing ability.
- Trial name
- EVAR (NCT02798783)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Vestibular Disorder, Hearing Loss, Sensorineural
Reading Outcomes in Children With Vestibular Loss
Vestibular loss can co-occur with hearing loss causing dual sensory deficits. This project examines vestibular loss as a contributing factor to reading difficulties for children with hearing loss, where previously only the…
- Trial name
- NCT05414903
- Testing
- Dynamic Visual Acuity, Reading Outcomes, Static Visual Acuity
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF), Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene
A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations
This is an observational study to examine the characteristics of gene-related hearing loss in pediatric participants with biallelic otoferlin (OTOF) Mutations, Gap Junction Beta 2 (GJB2) Mutations, or Digenic GJB2/Gap Junction…
- Conditions
- Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF), Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene, Digenic Mutations in GJB2/Gap Junction Beta 6 (GJB6) Genes
- Trial name
- ENSEMBLE (NCT06019481)
- Where
- 2 sites in United States
- Sponsor
- Regeneron Pharmaceuticals
Hearing Loss, Cochlear, Cytomegalovirus Congenital
Cytomegalovirus (CMV) Perilymphatic Fluid
In France, children cochlear implantation (CI) is performed 400 times per year. Causes of profound sensorineural hearing loss (SNHL) are represented by congenital malformation of the inner ear for 50 to 60%.
- Trial name
- CMVP (NCT04724265)
- Testing
- collection of sample of perilymphatic fluid during cochlear implantation
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neck Pain, Unilateral Blindness
Unilateral Blindness/ Unilateral Deafness-relation to Neck Pain
Neck pain is a common complaint in the general population affecting 10-15% of the general population. females more than men. Known risk factors are: Trauma, Repetitive lifting of heavy objects at work, driving vibrating vehicles…
- Conditions
- Neck Pain, Unilateral Blindness, Unilateral Deafness
- Trial name
- NCT00589407
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Primary Dystonia, Epilepsy
Assess Specific Kinds of Children Challenges for Neurologic Devices Study
The ASK CHILDREN study is intended to aid in future development of various neurologic devices (i.e. neuroprostheses). The ASK CHILDREN study seeks to use study information obtained to identify more efficient strategies in the…
- Conditions
- Primary Dystonia, Epilepsy, Hydrocephalus, Bladder Control
- Trial name
- NCT01191307
- Volunteers
- 16 people
- Sponsor
- Carlos Pena, PhD, MS
Otoferlin-related Auditory Synaptopathy, Hearing Impairment
Otoferlin Patient Registry and Natural History Study
This registry is designed to collect comprehensive information about the molecular genetic diagnoses of individuals with otoferlin-associated hearing impairment and clinical information to support a natural history study.
- Trial name
- NCT05946057
- Testing
- Molecular genetic testing and audiometry
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Tobias Moser
Vestibular Dysfunction, Hearing Loss
Impact of Vestibular Function on Deaf Infants' Activities of Daily Living
This non-interventional study aims to assess the impact of vestibular impairments on the daily life activities of deaf children aged 0 to 2 years old.
- Conditions
- Vestibular Dysfunction, Hearing Loss, Motor Development
- Trial name
- IVANS (NCT06909266)
- Testing
- OT Hope 0 - 5 ans Therapeutic tool, Qualitative interviews with parents
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wolfram Syndrome 1, Optic Atrophies, Hereditary
Does Recessive Optic Atrophy Due to WFS1 Exist?
All patients with Wolfram syndrome and recessive optic atrophy due to a mutation of the WFS1 from a single Center were included in a retrospective study.
- Trial name
- NCT07336966
- Testing
- analyse study
- Volunteers
- 45 people
- Sponsor
- Hôpital Necker-Enfants Malades
Prader-Willi Syndrome
Home-based SSP on Individuals With PWS
The Polyvagal Theory focuses on how function and structure changed in the vertebrate autonomic nervous system during evolution. The theory is named for the vagus, a major cranial nerve that regulates bodily state.
- Trial name
- NCT03871751
- Testing
- Safe and Sound Protocol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Usher Syndrome, Retinitis Pigmentosa
Study of Dietary N-3 Fatty Acids in Patients With Retinitis Pigmentosa and Usher Syndrome
OBJECTIVES: I. Examine the concentration of docosahexanoic acid (DHA) and other n-3 fatty acids in plasma, erythrocyte, and adipose tissue in patients with various forms of retinitis pigmentosa and Usher syndrome. II.
- Trial name
- NCT00004345
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Hearing Impaired Children
Effects of Pilates and Balance Proprioception Exercises on Hearing Impairment
Static balance is the ability to hold the body in a specific position and posture, while dynamic balance is the ability to maintain balance while moving.
- Trial name
- NCT06198049
- Testing
- Pilates Training, Balance Proprioception Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cytomegalovirus Infection
Valganciclovir Therapy in Infants and Children With Congenital CMV Infection and Hearing Loss
This is an international, multi-center, double-blind, placebo-controlled evaluation valganciclovir treatment for up to 54 children (up to 4 years of age) with virologically-confirmed congenital CMV infection and hearing loss.
- Trial name
- NCT01649869
- Testing
- Valganciclovir
- Where
- 18 sites in United States, United Kingdom
- Volunteers
- 54 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sensorineural Hearing Loss, Autoimmune Inner Ear Disease
A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
The purpose of this study is to determine if Anakinra (an interleukin-1 receptor antagonist) can improve hearing thresholds in those patients with Autoimmune Inner Ear Disease (AIED) that did not respond to oral steroid therapy…
- Trial name
- NCT01267994
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Andrea Vambutas