Clinical trials: Heart Defects
Congenital Heart Disease, Transition
Evaluation of Web-based Transition Education to Enhance Transition Readiness
The study looks to learn more about the helpfulness of web-based transition education and its effect on transition readiness and health service utilization in the adolescent and young adult congenital heart disease population.
- Conditions
- Congenital Heart Disease, Transition, Pediatric Congenital Heart Disease
- Trial name
- NCT03303248
- Testing
- Web-based Educational Intervention
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Atrial Septal Defect
Safety and Efficacy Study of Transcatheter Closure of Ostium Secundum ASDs
Evaluate the safety and efficacy of the GORE® CARDIOFORM ASD Occluder in the percutaneous closure of ostium secundum atrial septal defects (ASDs)
- Trial name
- ASSURED (NCT02985684)
- Testing
- GORE® CARDIOFORM ASD Occluder
- Where
- 22 sites in United States
- Volunteers
- 125 people
- Sponsor
- W.L.Gore & Associates
Turner Syndrome
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry
INSIGHTS is a registry research study that collects key information on medical history for girls and women with Turner syndrome and the clinical care they receive.
- Trial name
- INSIGHTS (NCT05052606)
- Testing
- No intervention
- Where
- 10 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- University of Colorado, Denver
Coarctation of the Aorta
Evaluating the Feasibility of Bioresorbable Iron-Based Covered Stent: A Clinical Trial
A single-center, feasible clinical study to Evaluate the Treatment of Iron Bioresorbable Covered Scaffold System in patients with Coarctation of the Aorta Diseases
- Trial name
- CoA-ICS-I (NCT07316855)
- Testing
- Implantation of Bioresorbable Iron-based Covered Aortic Stent
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shubo Song
RASopathies, Noonan Syndrome
National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype
RASopathies, including Noonan syndrome, involve dysmorphisms, metabolic alterations, and an unfavorable lipid profile. This study investigates lipid and glucose metabolism to improve patient care.
- Trial name
- NCT07464821
- Where
- 14 sites in Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Marfan Syndrome
APPLICATION OF THERAPEUTIC PHOTOGRAPHY AND EXPRESSIVE WRITING IN THE MANAGEMENT OF PATIENTS WITH MARFAN SYNDROME
This study explores the efficacy of therapeutic photography and expressive writing as interventions in routine practice for patients with Marfan syndrome.
- Trial name
- FOTOTEMA (NCT06872268)
- Testing
- Therapeutic photography and expressive writing, Expressive writing
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- IRCCS Policlinico S. Donato
Congenital Heart Disease
Transition Care Model for Adolescents With Congenital Heart Disease
The primary aim of this study is to assess the effectiveness of a standardized transition care model (TC) on the perceived mental and physical health of adolescents with congenital heart disease (CHD).
- Trial name
- TELEMACO (NCT05713591)
- Testing
- Transition care model
- Where
- Italy
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Congenital Heart Disease
Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery
The use of near infrared spectroscopy (NIRS) is a technique that has recently been incorporated by several other surgical specialties to measure tissue perfusion, such as in plastic surgery to allow for earlier detection of free…
- Trial name
- NCT07361523
- Testing
- Tissue oximeter (IntraOx)
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
mHealth, Adherence, Patient
Parental Experience in the Single Ventricle Interstage Utilizing a mHealth Innovation: A Comparative Case Study
The purpose of this study is to provide a rich description of the parental perspectives of utilizing a mHealth application for data transfer during the single ventricle interstage monitoring period.
- Trial name
- NCT03231020
- Testing
- Interview
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Children's Mercy Hospital Kansas City
Preterm, Patent Ductus Arteriosus
NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
Non-invasive tools for monitoring of course of disease are important and necessary in the treatment of pre-term/premature infants and sick neonates.
- Conditions
- Preterm, Patent Ductus Arteriosus, Sepsis, Asphyxia
- Trial name
- CE-NeoDoppler (NCT06646250)
- Testing
- NeoDoppler - CE certified
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Long QT Syndrome, Hypoglycemia
Frequency of Hypoglycemia in Children With Beta-blocker Treated Long QT-syndrome
The goal of this observational study is to investigate the frequency and characteristics of hypoglycemic episodes in children with long QT syndrome (LQTS) and beta-blocker treatment, specifically those receiving propranolol…
- Trial name
- LQThypo (NCT07233421)
- Testing
- Continuous Glucose Monitoring
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Congenital Heart Disease, Mechanical Ventilation Complication
Mechanical Ventilation During Cardiopulmonary Bypass
The study is about a protocol of protective mechanical ventilation during cardiopulmonary bypass used during cardiosurgery for the correction of congenital heart diseases, to evaluate what's the best for the lungs
- Conditions
- Congenital Heart Disease, Mechanical Ventilation Complication, Cardiopulmonary Bypass
- Trial name
- VENICE (NCT03629574)
- Testing
- Ventilation during cardiopulmonary bypass
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Padova
22q11 Deletion Syndrome
Indicated Prevention With Long-chain Polyunsaturated Omega-3 Fatty Acids in Patients With 22q11 Microdeletion Syndrome.
The purpose of the present trial is to investigate the effects of omega-3 PUFAs in individuals aged 12-26 years with 22q11DS at ultra-high risk for developing a first episode of psychosis.
- Trial name
- NCT02070211
- Testing
- omega-3 PUFAs, Standard care
- Where
- Holy See
- Volunteers
- 80 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Arrhythmogenic Right Ventricular Cardiomyopathy, Arrhythmogenic Right Ventricular Dysplasia
South Asian Arrhythmogenic Cardiomyopathy Registry
Arrhythmogenic Cardiomyopathy (ACM) is increasingly identified as an important cause of cardiac morbidity and mortality, especially of SCD, in a younger population.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, Arrhythmogenic Right Ventricular Dysplasia, Arrhythmogenic Ventricular Cardiomyopathy, Arrhythmogenic Cardiomyopathy
- Trial name
- NCT04895540
- Testing
- ECG, Echocardiography, Cardiac MRI
- Where
- 3 sites in United States, India
- Volunteers
- 100 people
- Sponsor
- Sheri Kashmir Institute of Medical Sciences
Growth Failure, Congenital Heart Disease
A Study to Evaluate the Effects of a New Formula on the Growth, Safety and Tolerance of Infants With Growth Failure
This study is a prospective, open-label, multi-site, growth, safety and tolerance study to evaluate a NF (New Formula). A minimum of 45 evaluable infants with confirmed growth failure will be enrolled.
- Trial name
- NCT03563391
- Testing
- New Infant Formula
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nutricia North America
Cardiac Anomalies
Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence on Children With Pre-existing Cardiac Conditions.
The goal of this study is to prospectively assess the diagnostic agreement of PEM fellow-performed cardiac POCUS and of AI-assisted interpretation using the Exo Iris probe, as compared to a complete echocardiography for detecting…
- Trial name
- POCUS-AI PEM (NCT07503158)
- Testing
- AI Pocus_Cardiac
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Hypoplastic Left Heart Syndrome
Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome
This is a Phase I study to determine the safety and feasibility of injections of autologous umbilical cord blood (UCB) cells into the right ventricle of Hypoplastic Left Heart Syndrome (HLHS) children undergoing a scheduled Glenn…
- Trial name
- NCT01883076
- Testing
- autologous cell-based delivery
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Timothy J Nelson, MD, PhD
Congenital Heart Disease
SVR III: Brain Connectome and Neurodevelopmental Outcomes
Patients with hypoplastic left heart syndrome and other single right ventricle lesions who have undergone the Fontan procedure have a high risk of neurodevelopmental disorders that affect quality of life and adulthood employment.
- Trial name
- SVRIII (NCT02692443)
- Testing
- Magnetic Resonance Imaging, Neurodevelopmental Testing
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Single-ventricle
Simple Non-invasive Breathing Device to Improve Pulmonary Flow Pusatility in Single Ventricle Post Fontan
This is a pilot study using a novel, minimal risk, portable, hands-free oral-positive pressure device (oPEP) in patients with Fontan palliation that will examine whether using this device in both the acute and chronic phase will…
- Trial name
- NCT05634226
- Testing
- Hands-free oral-positive pressure device (oPEP)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Tarek Alsaied
Congenital Heart Disease, Health Behavior
Heart2Heart for Teens With CHD
The goal of this clinical trial is to learn if teens living with congenital heart disease like and will use Heart2Heart and if it affects how they think and feel about e-cigarettes.
- Trial name
- NCT07764510
- Testing
- Heart2Heart
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Kristen Fox
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.