Clinical trials: Heart Failure Patients
Acute Coronary Syndrome, Acute Pulmonary Edema
Prior Statin Use and Risk of CHF, ALO and Malignant Arrhythmia in Indonesian Post-Acute Coronary Syndrome Patients
This study aims to evaluate the effect of statin for primary prevention, towards lowering the incidence of heart failure, acute lung edema, malignant arrhythmia and death in ACS patients.
- Conditions
- Acute Coronary Syndrome, Acute Pulmonary Edema, Arrhythmias, Cardiac, Heart Failure
- Trial name
- NCT03596931
- Testing
- Statins (Cardiovascular Agents)
- Where
- Indonesia
- Volunteers
- 130 people
- Sponsor
- Tarumanagara University
Congenital Cardiac Defect, Acute Renal Injury
Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery
Blood transfusion strategies in cardiac surgery are a research topic that has been studied more for adults. There is not enough data on this subject for children in studies.
- Conditions
- Congenital Cardiac Defect, Acute Renal Injury, Blood Transfusion Complication
- Trial name
- NCT06889272
- Testing
- blood transfusion
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people
- Sponsor
- Hacettepe University
Respiratory Failure, Shock
Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care
End-stage renal disease (ESRD) is an important risk factor for coronary and valvular cardiac disease leading to cardiac surgery.
- Conditions
- Respiratory Failure, Shock, Coagulopathy
- Trial name
- NCT04705701
- Testing
- Hemodialysis
- Sponsor
- Northwell Health
Congenital Heart Defects
Cardiac Resynchronization Therapy in Congenital Heart Defects
The objective of this multicentre prospective therapeutic study is to evaluate the effects of CRT on the right and left ventricular function of patients with CHD in the medium and long term.
- Trial name
- CARE-CHD (NCT00450684)
- Testing
- Implantation and testing of CRT
- Where
- 16 sites in Austria, Germany
- Volunteers
- 55 people
- Sponsor
- Competence Network for Congenital Heart Defects
Chronic Heart Failure
Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy
The study is performed to consider the effect of thiamine supplementation on symptoms and signs of patients with heart failure and systolic and diastolic function of left ventricle.
- Trial name
- NCT01115504
- Testing
- Thiamine
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Mashhad University of Medical Sciences
Chronic Heart Failure With Reduced Ejection Fraction
Safety and Tolerability During Open-label Treatment With LCZ696 in Patients With CHF and Reduced Ejection Fraction
The purpose of this study was to collect safety and tolerability data on LCZ696 in eligible PARADIGM-HF patients who received open-label investigational drug.
- Trial name
- NCT02226120
- Testing
- LCZ696
- Where
- 394 sites in United States, Argentina and 39 more
- Volunteers
- 1,980 people
- Sponsor
- Novartis Pharmaceuticals
Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Researchers are looking for a better way to treat children who have heart failure with left ventricular systolic dysfunction (LVSD).
- Trial name
- FIORE (NCT07188805)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 133 sites in United States, Argentina and 21 more
- Volunteers
- 111 people
- Sponsor
- Bayer
Coronary Artery Disease, End Stage Renal Disease
Prospective Study of End Stage Renal Disease Patients With Coronary Artery Disease Treated by Oral Nicorandil
Nicorandil is potentially effective to prevent cardiovascular events in patients with coronary artery disease (CAD) receiving hemodialysis.
- Trial name
- NCT01475123
- Testing
- Nicorandil
- Where
- Japan
- Volunteers
- 268 people
- Sponsor
- Kumamoto University
Heart Failure，Congestive, Left Ventricular Dysfunction
LV Endocardial CRT for Patients With Intermediate QRS Width
This pilot study is designed as a multi-centre cohort study determining the degree of LV reverse remodeling in patients with intermediate QRS widths (120-149ms) who undergo CRT implant with transseptal LV leads, and comparing to…
- Conditions
- Heart Failure，Congestive, Left Ventricular Dysfunction, Left Bundle-Branch Block
- Trial name
- EndoCRT (NCT03573427)
- Testing
- Trans-atrial septal placement LV lead for CRT
- Where
- 8 sites in Canada
- Sponsor
- Jaimie Manlucu
Diabetes, Hypertension
Quality IQ Patient Simulation Physician Practice Measurement and Engagement
This study will test the quality of physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and feedback.
- Conditions
- Diabetes, Hypertension, Depression, Osteoarthritis
- Trial name
- Q-IQ (NCT03800901)
- Testing
- Continuing Medical Education, Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Heart Disease, Dyspnea
Screening of Patients Admitted to a Local Hospital With Pocket-sized Ultrasound
Ultrasound (US) is widely used as a diagnostic tool in a hospital setting. In a medical department, diagnosis like heart failure or most kinds of heart diseases, hypervolemia, hypovolemia, pleural effusion, pericardial effusion…
- Conditions
- Heart Disease, Dyspnea, Aortic Disease, Kidney Disease
- Trial name
- NCT01081210
- Testing
- Ultrasound examination
- Where
- 2 sites in Norway
- Volunteers
- 400 people
- Sponsor
- Helse Nord-Trøndelag HF
Mitral Valve Insufficiency, Atrial Fibrillation
Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation
A large left atrial (LA) volume, which represents chronic diastolic dysfunction, is associated with a poor outcome, regardless of systolic function.
- Conditions
- Mitral Valve Insufficiency, Atrial Fibrillation, Heart Failure
- Trial name
- NCT01172184
- Testing
- Cardiac catheterization
- Where
- Taiwan
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
COVID-19 Pandemic
The Combined Usage of Clinical Physical Finding in Management of COVID 19 Patients
Physiological indicators such as blood pressure, heart rate, respiratory rate, and consciousness status of COVID-19 patients are used to apply the START (simple triage and rapid treatment, START), Modified Early Warning Score…
- Trial name
- NCT06528119
- Testing
- COVID 19 pandemic
- Where
- Taiwan
- Volunteers
- 10,000 people
- Sponsor
- St. Martin De Porress Hospital
Heart Failure
B-line by Lung US in Patients With Acute Decompensated Heart Failure
The purpose of this study is to evaluate that B-line detected by lung ultrasound before extubation in patients with acute decompensated heart failure can predict future risk of reintubation and clinical outcomes during admission…
- Trial name
- NCT04322851
- Testing
- Lung ultrasound
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Heart Failure
DIGITAL-HF - Digital Tools in Heart Failure - a Survey of Patient Usage (DIGITAL-HF)
Heart failure is a chronic health condition associated with significant symptoms, an increased need of support from the NHS, and typically is associated with a reduction in life expectancy.
- Trial name
- DIGITAL-HF (NCT05313880)
- Where
- 3 sites in United Kingdom
- Volunteers
- 254 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Heart Failure
High Intensity Aerobic Interval Training Versus Continuous Training in Heart Failure Patients.
To determine the effect of high intensity aerobic interval training versus continuous aerobic training in heart failure patients.
- Trial name
- NCT05948371
- Testing
- High Intensity interval Training, Continuous Aerobic training
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Heart Failure
Post Marketing Surveillance (PMS) of JARDIANCE in Chronic Heart Failure (CHF)
Study objective is to investigate the safety and effectiveness of long-term daily use of JARDIANCE® Tablets in patients with chronic heart failure (CHF) under real-world use.
- Trial name
- NCT05262764
- Testing
- JARDIANCE®
- Where
- Japan
- Volunteers
- 1,200 people
- Sponsor
- Boehringer Ingelheim
Heart Failure, Congestive
Organized Program To Initiate Lifesaving Treatment In Hospitalized Patients With Heart Failure (OPTIMIZE-HF)
This program is designed to improve medical care and education of hospitalized patients with heart failure and accelerate the initiation of evidence-based heart failure guideline recommended therapies by administering them before…
- Trial name
- NCT00344513
- Testing
- Beta-blockers including Carvedilol, ACE inhibitors
- Volunteers
- 50,000 people
- Sponsor
- GlaxoSmithKline
Acute Heart Failure
Pharmacokinetics & Safety of Serelaxin on Top of Standard of Care Therapy in Pediatric Patients With Acute Heart Failure
The purpose of the study was to evaluate the safety, tolerability and pharmacokinetics of an intravenous infusion of serelaxin on top of standard of care therapy, in pediatric patients with acute heart failure (AHF)
- Trial name
- RELAX-PEDS-PK (NCT02151383)
- Testing
- Serelaxin
- Where
- 10 sites in United States, Germany and 2 more
- Volunteers
- 12 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization
Intravenous Iron Sucrose for Acute Decompensated Heart Failure Patients With Reduced Ejection Fraction and Iron Deficiency
Iron deficiency (ID) affects about 25% of the global population, presenting with symptoms of fatigue, weakness, and impaired cognitive function.
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization, Iron Deficiency
- Trial name
- IronSucroseHF (NCT06703411)
- Testing
- Iron Sucrose IV, Standard Medical Therapy
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Cheng-Hsin General Hospital