Clinical trials: Hematologic Test
Malaria, Placental Malaria
Malaria Rapid Diagnostic Tests (RDTs) in Pregnancy: Detection of Placental Malaria
This study seeks to determine whether screening pregnant women for malaria with malaria rapid diagnostic tests (RDTs) may detect placental infection and predict risk of poor birth outcomes due to malaria in areas of varied…
- Conditions
- Malaria, Placental Malaria, Malaria in Pregnancy
- Trial name
- NCT01555255
- Where
- 2 sites in Burkina Faso, Uganda
- Volunteers
- 1,205 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Glucose-6-Phosphate Dehydrogenase Deficiency
Evaluation of Different G6PD Testing Platforms
In this study the investigators propose to evaluate the performance of several G6PD testing platforms.
- Trial name
- NCT02104518
- Where
- Indonesia
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- PATH
the Use of Radiofrequency Ablation in Form of TECAR(Capacitive and Resistive Transfer Energy) in Chronic Pain of Sickle Cell Disease Patients
The Radiofrequency Therapy in Management of Sickle Cell Disease Chronic Pain RCT Tested the Effect of TECAR Therapy on Sickle Cell Disease Chronic Pain.
The goal of this clinical trial study is to assess effect of radiofrequency on chronic pain of sickle cell disease pain . All SCA participants who fulfilled inclusion and exclusion criteria were 220; only 170 participant agreed…
- Trial name
- RCT/TECAR (NCT07066072)
- Testing
- Tecar therapy (TECAR: Capacitive and Resistive Energy Transfer)., standard pharmacological therapy in sickle cell disease like hydroxyurea,paracetamol,ibubrofen and blood transfusion if needed
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Cairo University
Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia
Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs With and Without Airflow Obstruction
Pulmonary arteriovenous malformations (PAVMs) are a rare vascular condition affecting the lungs. PAVMs lead to low blood oxygen levels, yet are very well tolerated by patients.
- Conditions
- Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia, Asthma, COPD
- Trial name
- ExercisePAVM2 (NCT02458703)
- Testing
- Cardiopulmonary exercise test
- Volunteers
- 60 people
- Sponsor
- Imperial College London
Leukemia
Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 Trial
RATIONALE: Testing for minimal residual disease in blood samples from patients with acute lymphoblastic leukemia may help doctors plan better treatment.
- Trial name
- NCT01629745
- Testing
- gene expression analysis, flow cytometry, laboratory biomarker analysis
- Volunteers
- 99 people
- Sponsor
- Children's Oncology Group
Food Protein-Induced Enterocolitis Syndrome, Allergies
Novel Blood Test to Predict Safe Foods for Infants and Toddlers With Food Protein-induced Enterocolitis Syndrome (FPIES)
The aim of this study is to validate a blood test that can identify safe foods for food protein-induced enterocolitis syndrome (FPIES).
- Conditions
- Food Protein-Induced Enterocolitis Syndrome, Allergies, Pediatric Disorder
- Trial name
- NCT04644783
- Testing
- Blood test assay
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Pain, Anxiety
The Effects of Medical Clowns in Children Undergoing Blood Tests
The investigators hypothesized that the participation of therapeutic clowns in the pediatric emergency department procedure room would reduce anxiety, improve the level of cooperation children can provide and avoid some of the…
- Trial name
- NCT01396876
- Testing
- clown
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia
Ex Vivo Drug Sensitivity Testing and Mutation Profiling
This study is a prospective, non-randomized feasibility study. Freshly isolated tumor cells from patients will be screened using state-of-the-art viability assay designed for ex vivo high-throughput drug sensitivity testing…
- Conditions
- Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Large Cell Lymphoma, Refractory Childhood Acute Lymphoblastic Leukemia
- Trial name
- NCT03860376
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Florida International University
Kidney Cancer
Anti-IMP3 Autoantibody and MicroRNA Signature Blood Tests in Finding Metastasis in Patients With Localized or Metastatic Kidney Cancer
This research trial studies the development of a blood test for detecting anti-insulin-like growth factor II mRNA binding protein 3 (anti-IMP3) antibody and micro ribonucleic acid (microRNA) in patients with renal cell carcinoma…
- Trial name
- NCT00806650
- Testing
- gene expression analysis, protein expression analysis, diagnostic laboratory biomarker analysis
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- City of Hope Medical Center
Hematologic Diseases, Bacteremia Sepsis
Effect of dRAST on Treatment for Bacteremia in Patients With Hematologic Diseases
The purpose of this study is to evaluate whether the use of direct rapid antibiotic susceptibility test (dRAST), in addition to the current standard antibiotic susceptibility test, can increase the proportion of patients with…
- Trial name
- NCT03611257
- Testing
- dRAST, Current standard method
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Seoul National University Hospital
Hemophilia A, Anticoagulant Therapy
Home Monitoring in Hemophilia A
Rationale: A novel point-of-care device capable of measuring factor VIII (FVIII) activity and thrombin generation (TG) is currently under development.
- Conditions
- Hemophilia A, Anticoagulant Therapy, Monitoring, Point of Care Testing
- Trial name
- NCT06702579
- Where
- Netherlands
- Volunteers
- 19 people
- Sponsor
- Radboud University Medical Center
Acute Myeloid Leukemia
Interleukin-21 (IL-21)- Expanded Natural Killer Cells for Induction of Acute Myeloid Leukemia
Relapsed acute myeloblastic leukemia (AML) requires remission prior to allogeneic Hematopoietic Stem Cell Transplant (HSCT) for optimal survival, but is a disease with poor response to chemotherapy.
- Trial name
- NCT02809092
- Testing
- NK Cells + Chemotherapy Starting
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Retinoblastoma, Secondary Primary Malignancies After Retinoblastoma
New Strategies to Detect Cancers in Carriers of Mutations in RB1
Rationale: Individuals with a cancer predisposition due to a mutation in the paradigm tumor suppressor gene RB1, have a high risk to develop the childhood cancer retinoblastoma (Rb).
- Trial name
- NIRBTEST (NCT04164134)
- Testing
- blood draw
- Where
- 3 sites in France, Germany and 1 more
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Eosinophilic Esophagitis Caused by Food (Disorder)
EoE Food Test Pilot Study
The objective of this study is to determine the performance characteristics of a series of novel, non-invasive allergen-activated T cell assays designed to identify Eosinophilic esophagitis (EoE) causal foods, when used in…
- Trial name
- NCT07023380
- Testing
- Assay directed diet change
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Philadelphia
Trauma Centers/Statistics & Numerical Data, Trauma Blunt
Medical,Nursing Record,PE, Blood Test and Radiological Examination ,Morality and Mobility of Multiple Trauma Patient
This study aims to analyze statistical data on physiological examination values, blood test results, and radiological findings in patients admitted to the emergency department for severe trauma.
- Conditions
- Trauma Centers/Statistics & Numerical Data, Trauma Blunt, Trauma (Including Fractures), Trauma Abdomen
- Trial name
- trauma (NCT07903727)
- Testing
- Collect results of trauma patients
- Volunteers
- 700 people
- Sponsor
- St. Martin De Porress Hospital
Colorectal Cancer
Improving Fecal Occult Blood Test Completion Rates Among Veterans
This is a 4-arm cluster randomized controlled trial to evaluate whether patient financial incentives directly integrated into primary care can improve fecal occult blood test (FOBT) completion rates.
- Trial name
- NCT01516489
- Testing
- Stage 1, Stage 2
- Where
- United States
- Volunteers
- 1,549 people
- Sponsor
- Corporal Michael J. Crescenz VA Medical Center
Leukemia
Comparison of Laboratory Test Results of Minimal-Residual Disease in Samples From Patients With Acute Myeloid Leukemia
RATIONALE: Diagnostic procedures that find residual disease may help predict if the disease will come back in patients diagnosed with acute myeloid leukemia.
- Trial name
- NCT01498302
- Testing
- diagnostic laboratory biomarker analysis, flow cytometry
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Hemophilia
Does the Thrombin Generation Test Performed During the Pharmacokinetic Profile of the Substitutive Factor VIII Bring Benefits to the Personalized Treatment of Pediatric Patients and Adult Hemophilia A Patients Under Prophylaxis ?
In the context of hemophilia, it is well know that the level of factor VIII alone does not reflect the clinical phenotype of the patients in an accurate way.
- Trial name
- NCT02803502
- Testing
- Chronometric method, Chromogenic method, Thrombin generation test (TGT)
- Where
- 5 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Brugmann University Hospital