Clinical trials: Hip Replacement
Total Hip Replacement, Blood Loss
An Algorithm for Predicting Blood Loss and Transfusion Risk in Fast Track Total Hip Arthroplasty
Aim of these study is to create an algorithm, using data from patients that undergoing total hip arthroplasty, to predict blood loss after surgery and permit a safe domestic discharge.
- Trial name
- NCT02750852
- Testing
- Total hip arthroplasty, blood loss analysis
- Volunteers
- 124 people
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
Osteoarthritis, Hip
Change of Cognitive Performance Through Hip Replacement
The purpose of this study is to investigate the effectiveness of a hip arthroplasty for chronic pain, caused by a unilateral primary Coxartrhrose, regarding the cognitive performance.
- Trial name
- KogniTEP (NCT02997891)
- Testing
- everyday activity, cognitive performance
- Where
- 2 sites in Germany
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
28mm Ceramic-on-Ceramic Total Hip Replacement Study
This study is intended to gather medium (0-5 years) and long-term (6-10 years) information regarding the performance and safety of the commercially available Ceramax™ Ceramic on Ceramic Total Hip System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
- Trial name
- COC28 (NCT01657435)
- Testing
- Ceramax Acetabular System
- Where
- 13 sites in United States, Canada
- Volunteers
- 185 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis
Cost Efficacy of a Clinical Pathway to Patients Undergoing Hip and Knee Replacement Surgery
In this randomised study a proactive care and rehabilitation intervention is compared to the current care and rehabilitation in patients undergoing primary hip and knee replacement surgery.
- Trial name
- NCT00175201
- Testing
- Proactive care and rehabilitation
- Where
- Denmark
- Volunteers
- 247 people
- Sponsor
- University of Aarhus
Hemorrhage, Arthroplasty, Replacement, Hip
Tranexamic Acid vs. Quixil - Reducing Blood Loss in Joint Replacement
We will compare the effectiveness of Quixil and Tranexamic acid in reducing bleeding during hip and knee joint replacements.
- Conditions
- Hemorrhage, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT00378872
- Testing
- IV Tranexamic acid 10mg/kg pt body weight, Quixil topical sealant
- Where
- United Kingdom
- Volunteers
- 132 people
- Sponsor
- Golden Jubilee National Hospital
Bleeding, Transfusion Related Complication
Use of Transexamic Acid in Hip Replacement
Studies have shown that tranexamic acid reduces blood loss and transfusion need in patients undergoing total hip arthroplasty. However, no to date, no study has been large enough to determine definitively whether the drug is safe…
- Trial name
- NCT02587845
- Testing
- Tranexamic Acid (IV), Tranexamic Acid (Topical)
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Arthroplasty Total Hip Replacement
The Relationship Between Operative and Radiologic Stem Version
Investigators prospectively evaluate the accuracy of intraoperative stem anteversion in 40consecutive total hip arthroplasties.
- Trial name
- NCT02552173
- Testing
- The Relationship Between Operative and Radiologic Stem Version
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Avascular Necrosis
A Clinical Investigation of ArComXL® Polyethylene in Total Hip Replacement
The purpose of this data collection is to determine long term survival rate of ArComXL® highly cross-linked polyethylene
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- NCT00698152
- Where
- 5 sites in United States
- Volunteers
- 149 people
- Sponsor
- Zimmer Biomet
Psychological Stress, Cardiopulmonary Bypass Surgery
CARINAE for Stress Relief in Perioperative Care
Preventing pre-surgical stress can help patients achieve positive outcomes on health and well-being. However, very few patients receive adequate stress relief support prior to a surgical procedure.
- Conditions
- Psychological Stress, Cardiopulmonary Bypass Surgery, Coronary Artery Bypass Surgery, Cardiac Valve Replacement
- Trial name
- CARINAE (NCT05184725)
- Testing
- SaMD CARINAE
- Where
- 5 sites in Italy, Netherlands and 1 more
- Volunteers
- 50 people
- Sponsor
- Adhera Health, Inc.
Hip Replacement
A Novel Study Evaluating Patients Awaiting Total Hip Arthroplasty (PRIORITEES)
Hip replacements are one of the NHS's highest volume procedures, with ~14,000 operations per month before the onset of the COVID-19 pandemic.
- Trial name
- PRIORITEES (NCT06178185)
- Where
- United Kingdom
- Volunteers
- 240 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Knee Arthropathy, Hip Arthropathy
Analysis of Influencing Factors and Construction of Prediction Models of Artificial Joint Replacement in China
The project intends to analyze the epidemiological characteristics, risk factors, complications and resource utilization of artificial joint replacement in China through the inpatient data collected by the Hospital Quality…
- Conditions
- Knee Arthropathy, Hip Arthropathy, Shoulder Arthropathy, Ankle Arthropathy
- Trial name
- NCT05170321
- Where
- China
- Volunteers
- 600,000 people
- Sponsor
- Xiangya Hospital of Central South University
Osteoarthritis
Weight-bearing Recommendation After Replacement of the Hip or Knee Joint
Despite the widespread use of total hip and knee arthroplasty, there is a notable lack of consensus regarding postoperative treatment, mostly because of the lack of well-designed studies testing the efficacy and effectiveness of…
- Trial name
- NCT00266396
- Testing
- Recommend full weight-bearing, Recommend parital weight-bearing
- Where
- 4 sites in Germany
- Volunteers
- 352 people
- Sponsor
- Verein zur Förderung der Rehabilitationsforschung in Schleswig-Holstein
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
A Study of Patients Undergoing Total Knee and Hip Arthroplasty at a Regional Hospital in Denmark
This project will be a descriptive, hypothesis-generating study. The aim is to identify risk factors for poor response to rehabilitation programs after TJR and use these to identify patients who are most susceptible to poor…
- Trial name
- NCT03008967
- Testing
- Arthroplasty and postoperative rehabilitation.
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Bornholms Regionskommune
Osteoarthritis, Hip, Arthroplasty, Replacement, Hip
Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen
The primary aim of this randomised trial is to determine the effects of a short peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID), ibuprofen, on the long-term consequences of ectopic bone…
- Conditions
- Osteoarthritis, Hip, Arthroplasty, Replacement, Hip, Arthritis, Rheumatoid
- Trial name
- NCT00145730
- Testing
- Ibuprofen
- Volunteers
- 1,000 people
- Sponsor
- The George Institute
Muscle Weakness
Maximal Strength Training in Patients Undergoing Total Hip Arthroplasty
Conventional rehabilitation after total hip arthroplasty (THA) does not seem to restore muscular strength or walking speed. Three-5 years after surgery patients are still not fully rehabilitated.
- Trial name
- NCT02498093
- Testing
- Maximal strength training, conventional rehabilitation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Arthroplasty, Replacement, Hip
Effects of Photobiomodulation Therapy (PBMT) in Total Hip Arthroplasty
Osteoarthritis (OA), a chronic degenerative muscle disease characterized by cartilage wear, causes progressive joint deformity and loss of function leading to the indication of total hip arthroplasty (THA), when conservative…
- Trial name
- NCT02970890
- Testing
- Portable Pain Away™
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Adriane Aver Vanin
Arthroplasty, Replacement, Hip, Patient Education
Early Mobilization and Postoperative Complications in Hip Arthroplast
Orthopedic surgical procedures, particularly total hip replacement, are of great importance in the older population in terms of regaining functional independence, reducing pain, and improving quality of life.
- Conditions
- Arthroplasty, Replacement, Hip, Patient Education, Patient Education and Early Mobilization After Total Hip Arthroplasty
- Trial name
- NCT07867717
- Testing
- Early Mobilization Education, Routine Postoperative Care
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cyprus Aydin University
Total Hip Arthroplasty, Tranexamic Acid Administration
Combined Tranexamic Acid Use in Total Hip Replacement Surgery
This prospective study evaluates whether combined intravenous and topical administration of tranexamic acid (TXA) can safely reduce blood loss in patients undergoing primary total hip replacement surgery.
- Conditions
- Total Hip Arthroplasty, Tranexamic Acid Administration, Perioperative Blood Loss, Coagulation Monitoring Using ROTEM
- Trial name
- NCT07610863
- Testing
- Intravenous Tranexamic Acid, Combined Intravenous and Intraarticular Tranexamic Acid
- Where
- Czechia
- Volunteers
- 58 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Infection of Total Hip Joint Prosthesis, Implants
Immunology of Failing Metal-on-Metal Hip Replacement
Metal-on-metal total hip replacement (MoM THR) has been targeted at younger patients with anticipated long-term survival since the bearing surfaces wear less than the traditional metal-on-plastic (MoP) replacements.
- Trial name
- NCT01517737
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Osteoarthritis, Arthritis
Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty
The purpose of the study is to determine whether crosslinked Marathon and standard Enduron polyethylene liners show differences in bone loss around the hip implant.
- Conditions
- Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT01121146
- Testing
- Total Hip Replacement
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Anderson Orthopaedic Research Institute