Clinical trials: Hospitalized Patients
Acute Respiratory Distress Syndrome, Lung Diseases
SILtuximab in Viral ARds (SILVAR) Study
This study will evaluate the efficacy and safety of siltuximab compared with normal saline in combination with standard of care (SOC) in selected hospitalized patients with COVID-19 previously treated with corticosteroids or…
- Conditions
- Acute Respiratory Distress Syndrome, Lung Diseases, Pneumonia, Respiratory Tract Infections
- Trial name
- SILVAR (NCT04616586)
- Testing
- Siltuximab, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 555 people
- Sponsor
- RECORDATI GROUP
Community-acquired Pneumonia
Characteristics of Hospitalized Patients With Community-acquired Pneumonia
At present, the epidemiological characteristics and the distribution of pathogens of community-acquired pneumonia in Shandong Province are not clear.
- Trial name
- NCT06065618
- Testing
- Without intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qianfoshan Hospital
COVID-19 Pneumonia
A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia
This study will evaluate the efficacy and safety of combination therapy with remdesivir plus tocilizumab compared with remdesivir plus placebo in hospitalized patients with COVID-19 pneumonia.
- Trial name
- REMDACTA (NCT04409262)
- Testing
- Remdesivir, Tocilizumab
- Where
- 54 sites in United States, Brazil and 2 more
- Volunteers
- 649 people
- Sponsor
- Hoffmann-La Roche
Hospitalization in a Post-Resuscitation Rehabilitation Care Units
Characteristics and Evolution of Hospitalized Patients in Post-Resuscitation Rehabilitation Care Units (SRPR)
Non-interventional cohort study (on data), prospective national multicenter. Inclusion of patients as they enter in a post-intensive care rehabilitation unit (SRPR) .
- Trial name
- Cohorte-SRPR (NCT03768700)
- Testing
- Data gathering
- Where
- 10 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non ST Segment Elevation Acute Coronary Syndrome
Differential Diagnosis and Risk Stratification in Patients With Suspected NSTEACS
To evaluate possibilities of rapid differential diagnosis and risk stratification in patients urgently admitted to the CCU with a suspected acute coronary syndrome without persistent ST-segment elevation (NSTEACS).
- Trial name
- NCT04400500
- Testing
- Approaches to differential diagnosis and risk stratification
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- National Research Center for Preventive Medicine
Heart Failure, Congestive
Organized Program To Initiate Lifesaving Treatment In Hospitalized Patients With Heart Failure (OPTIMIZE-HF)
This program is designed to improve medical care and education of hospitalized patients with heart failure and accelerate the initiation of evidence-based heart failure guideline recommended therapies by administering them before…
- Trial name
- NCT00344513
- Testing
- Beta-blockers including Carvedilol, ACE inhibitors
- Volunteers
- 50,000 people
- Sponsor
- GlaxoSmithKline
Acute Heart Failure
Pharmacokinetics & Safety of Serelaxin on Top of Standard of Care Therapy in Pediatric Patients With Acute Heart Failure
The purpose of the study was to evaluate the safety, tolerability and pharmacokinetics of an intravenous infusion of serelaxin on top of standard of care therapy, in pediatric patients with acute heart failure (AHF)
- Trial name
- RELAX-PEDS-PK (NCT02151383)
- Testing
- Serelaxin
- Where
- 10 sites in United States, Germany and 2 more
- Volunteers
- 12 people
- Sponsor
- Novartis Pharmaceuticals
Sickle Cell Disease
Safety Evaluation of DREPADOM - Home Care Services and Hospitalizations for Sickle Cell Disease Patients
The objective of this study is to evaluate the incidence of ACS within the DREPADOM system and compare it to expected incidences of ACS (historic cohorts of PRESEV1 and PRESEV2)
- Trial name
- DREPADOM (NCT05649280)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Soutien aux Actions contre les Maladies du Globule Rouge
Cystic Fibrosis
Effects of an Early Rehabilitation Program During Hospitalization in Patients With Cystic Fibrosis
Studies demonstrate that exercise increases the maximal oxygen uptake, peak oxygen consumption, reduce effort-induced lactic acid production, and increase skeletal muscle oxidative capacity, as well as psychological aspects such…
- Trial name
- NCT03100214
- Testing
- Exercise, Control
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Infections, Heart Diseases
Effect of Synapse Medicine Decision Support on Inpatient Pharmacist Efficacy and Efficiency
Adverse drug events (ADE) are common and dangerous in the hospital and following discharge to the ambulatory setting. One cause of ADEs in both settings is medication regimen inappropriateness, including polypharmacy, drug-drug…
- Conditions
- Infections, Heart Diseases, Lung Diseases, Kidney Diseases
- Trial name
- NCT05459155
- Testing
- Synapse medicine platform
- Where
- United States
- Volunteers
- 1,485 people
- Sponsor
- Brigham and Women's Hospital
Injuries, Multiple, Norway/Epidemiology
Trauma Registration at St. Olavs Hospital 2000-2003
St. Olavs Hospital is a trauma referral center in the region of Midtnorge. Admitting trauma patients locally and those referred from hospitals in Nord-Trøndelag, Sør-Trøndelag and Møre-Romsdal.An active trauma team was defined in…
- Conditions
- Injuries, Multiple, Norway/Epidemiology, Trauma Centers/Statistics & Numerical Data, Trauma, Multiple
- Trial name
- NCT00184470
- Volunteers
- 1,000 people
- Sponsor
- Norwegian University of Science and Technology
COVID-19
The Evaluation of Hemostasis in Hospitalized COVID-19 Patients
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been shown to predispose patients to thrombotic diseases (venous and arterial) with…
- Trial name
- TARGET-COVID (NCT04493307)
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- LifeBridge Health
Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization
Intravenous Iron Sucrose for Acute Decompensated Heart Failure Patients With Reduced Ejection Fraction and Iron Deficiency
Iron deficiency (ID) affects about 25% of the global population, presenting with symptoms of fatigue, weakness, and impaired cognitive function.
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization, Iron Deficiency
- Trial name
- IronSucroseHF (NCT06703411)
- Testing
- Iron Sucrose IV, Standard Medical Therapy
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Cheng-Hsin General Hospital
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
COVID-19
A Real World Study of Paxlovid for the Treatment of Hospitalized Patients Confirmed With COVID-19
The study was designed to analyze the efficacy and safety of Paxlovid for the treatment of COVID-19.
- Trial name
- NCT05387369
- Testing
- Paxlovid
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Huashan Hospital
Virtual Reality
The WOW Project (WOW): Wonders Of The World Through Virtual Reality for Hospitalized Children
Hospitalized pediatric patients are unable to leave the hospital to engage in traditional learning environments. Patients often feel depressed, disconnected from learning, and socially withdrawn.
- Trial name
- WOW (NCT06911996)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Stanford University
Focus: Hospitalized Patients
Hospital to Home Outcomes
Home Nurse Visit post discharge.
- Trial name
- NCT02081846
- Testing
- Nurse Home Visit, Standard of Care
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma
Impact of Omalizumab on Corticosteroid Use, Emergency Room Visits and Hospitalizations
A retrospective database analysis to evaluate the impact of omalizumab on the use of corticosteroid, emergency-department visits and hospitalizations among patients with uncontrolled asthma and using high-dose Inhaled…
- Trial name
- NCT01460862
- Sponsor
- Novartis Pharmaceuticals
Surgical Condition, Obstetrical Condition
Validity of Information Employed to Generate Standardized Mortality Ratios Using Hospital Administrative Databases (RNMH)
In a retrospective cross-sectional study, investigators aimed to valid the variables employed to generate standardized mortality ratio from hospital administrative databases.
- Conditions
- Surgical Condition, Obstetrical Condition, Hospitalization in Acute Care
- Trial name
- RNMH (NCT02816320)
- Testing
- Hospitalization
- Volunteers
- 715 people
- Sponsor
- Hospices Civils de Lyon
COVID-19
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after you take it), and efficacy (how well a study…
- Trial name
- NCT05261139
- Testing
- nirmatrelvir, ritonavir
- Where
- 73 sites in United States, Bulgaria and 5 more
- Volunteers
- 160 people
- Sponsor
- Pfizer