Clinical trials: Households
Immunosuppression
Role of Children in Transmission of COVID-19 to Immunocompromised Patients
This is a study of immunosuppressed individuals living in households with and without children to assess the role of household contact with children in the transmission of SARSCoV-2 to immunocompromised individuals.
- Trial name
- NCT04407546
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Infection, Coronavirus, Infections
Xofluza-Wearables Feasibility-Study
The goal of this prospective, interventional, single-center study is to assess whether the early detection of Influenza with smart wearable device algorithms and alerting, rapid testing, and subsequent Baloxavir treatment…
- Conditions
- Infection, Coronavirus, Infections, Influenza, Transplant
- Trial name
- NCT06161454
- Testing
- Baloxavir Marboxil
- Where
- United States
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Obesity
Study of Health Assessment and Risk Evaluation in Aboriginal Peoples Action Toward Obesity Prevention (SHARE-AP Action)
The purpose of this study is to develop an effective intervention strategy to prevent \& reduce obesity among a high risk cohort of Aboriginal families.
- Trial name
- NCT00334269
- Testing
- Health messaging at weekly home visits by health counsellor, Weekly home delivery of bottled spring water, Weekly afterschool physical activity program for 5-18y.o.
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Population Health Research Institute
Tuberculosis Infection, Tuberculosis
BCG Revaccination in Children and Adolescents
Bacille Calmette Guerin (BCG) vaccine is one of the most used vaccines of the world, to reduce the risks of natural tuberculous infection.
- Trial name
- BRiC (NCT05330884)
- Testing
- BCG vaccine, Oral Chemoprophylaxis
- Where
- India
- Volunteers
- 9,200 people, healthy volunteers welcome
- Sponsor
- Tuberculosis Research Centre, India
HIV Seropositivity, Tuberculosis
Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients
A multicenter, randomized, stratified, open-label, phase IV trial among HIV-positive persons (PLHIV) on antiretroviral therapy (ART), or HIV-negative household contacts of patients with rifampicin-sensitive pulmonary tuberculosis…
- Conditions
- HIV Seropositivity, Tuberculosis, Household Contact
- Trial name
- 1 to 3 (NCT05118490)
- Testing
- Daily rifapentine and isoniazid for 4 weeks, Weekly rifapentine and isoniazid for 12 weeks
- Where
- 4 sites in India, Indonesia and 2 more
- Volunteers
- 1,000 people
- Sponsor
- The Aurum Institute NPC
Poverty, Child Malnutrition
The Effect of a Cash Transfer Program and Preventive Nutrition Packages on Household Welfare and Child Nutritional Status in Mali
In the last two decades, cash transfer (CT) programs have emerged as a popular approach to long-term poverty alleviation. While the main goal of cash transfer programs is to reduce poverty, they also have the potential to improve…
- Trial name
- Jigisemejiri (NCT02858011)
- Testing
- Cash distribution during first 36 months, Accompanying information sessions on health, child nutrition, household economics and education during first 36 months, Preventive Nutrition Packages during last 12 months
- Where
- Mali
- Volunteers
- 4,320 people
- Sponsor
- International Food Policy Research Institute
Infective Organism Causing Respiratory Diseaseand Meningitis
A Prospective Household Observational Cohort Study of Influenza, Respiratory Syncytial Virus and Other Respiratory Pathogens Community Burden and Transmission Dynamics in South Africa
Title: A Prospective Household observational cohort study of Influenza, Respiratory Syncytial virus and other respiratory pathogens community burden and Transmission dynamics in South Africa (The PHIRST Study) This study will…
- Trial name
- PHIRST-SA (NCT02519803)
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- National Institute for Communicable Diseases, South Africa
Hygiene, Handwashing
Intervention to Change Handwashing Behaviour in India
The research will test the hypothesis that a scalable behaviour change intervention can improve hand-washing practices in rural Indian households.
- Conditions
- Hygiene, Handwashing, Behaviour
- Trial name
- NCT04929860
- Testing
- social marketing campaign
- Where
- India
- Volunteers
- 1,747 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Nutrition, Healthy
Food FARMacia: Reducing Childhood Obesity in Households With Food Insecurity
The goal of this clinical trial is to test whether the Food FARMacia intervention to reduce food insecurity is feasible and accepted among families with an infant age 6 to less than 18 months receiving pediatric primary care.
- Trial name
- NCT06051591
- Testing
- Food FARMacia Program, Self-directed meal preparation support
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Poverty, Child Health
Targeting Child Mental Health and Household Poverty
Living in poverty has long-lasting negative effects on children's mental health and on their mental health in adulthood. Child poverty is very common, affecting 17% of Canadian children.
- Conditions
- Poverty, Child Health, Behavior Problem
- Trial name
- NCT05667675
- Testing
- Community Support Worker, Control
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Imaan Bayoumi
Zinc Deficiency, Diarrhea
Water-based Zinc Intervention Trial in Zinc Deficient Children
The overall aim of this trial is to determine whether the use of the household-based water treatment device Life Straw Family (LSF) can be an effective strategy to improve zinc status and health status of vulnerable populations…
- Trial name
- NCT01472211
- Testing
- zinc enriching filter (LifeStrawFamily), disinfection tablets
- Where
- Benin
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Health Behavior
Using Emails and Personalized Phone Calls to Increase Affordable Care Act Marketplace Enrollment Among Households Losing Medicaid
Since its passage in 2010, the Affordable Care Act (ACA) has helped reduce the uninsured rate to record lows, but changes in insurance coverage over time, known as churn, remain a concern.
- Trial name
- NCT05327712
- Testing
- Control group, Email only, Phone only
- Where
- United States
- Volunteers
- 2,173 people
- Sponsor
- Office of Evaluation Sciences
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
COVID-19
COVID-19 Household Transmission Study
This study will test and follow persons quarantined at home after testing positive for SARS-CoV-2 (COV) aged 18 years and older and their household members aged 1 year and older.
- Trial name
- CO-HOST (NCT04445233)
- Testing
- COVID-19 IgM-IgG Rapid Test
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy
Household Air Pollution and Pregnancy Outcome
Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing…
- Trial name
- HAP (NCT02394574)
- Testing
- Clean Cookstove, Traditional Cookstove
- Where
- Nigeria
- Volunteers
- 307 people
- Sponsor
- University of Chicago
SARS-CoV-2
Within Household Transmission of COVID-19 Infections
In the absence of a vaccine, the spread of SARS-CoV-2 can only be mitigated via non-pharmaceutical interventions that reduce the risks of forward transmission.
- Trial name
- VERDI (NCT05430516)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
SARS CoV 2 Infection, SARS CoV 2 Vaccination
COVID-19 Transmission and Morbidity in Malawi
SARS-CoV-2 transmission was expected to have a devastating impact in sub-Saharan African countries. Instead, morbidity and mortality rates in nearly the whole region are an order of magnitude lower than in Europe and the…
- Trial name
- COVID-TMM (NCT05973084)
- Where
- 2 sites in United States, Malawi
- Volunteers
- 1,500 people
- Sponsor
- Boston University
Behavior
Integrating Nutrition Education & Household Food Production for Child Nutrition
In Ethiopia, a child-centered counseling approach is hypothesized to be more effective than the current nutrition and health education when investment on home-based food production is used as a platform for nutrition education.
- Trial name
- NCT02249286
- Testing
- Child Centered Nutrition Counseling, no intervention
- Volunteers
- 404 people
- Sponsor
- Jimma University
Tuberculosis
Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries
The ERASE - TB study will be conducted in order to fill a critical unmet need for tuberculosis control. Persons who are in contact with an infectious TB case may become infected themselves.
- Trial name
- ERASE-TB (NCT04781257)
- Testing
- New test candidates
- Where
- 3 sites in Mozambique, Tanzania and 1 more
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Michael Hoelscher
Coronavirus Infection
Serologic Testing of Household Contacts of Confirmed Cases of COVID-19
SARS-CoV-2 has now crossed the 1 million number of cases and tens of thousands of deaths. It´s R0 has been calculated between 2 and 5.7 solely based on clinical symptoms but it is estimated to likely be higher.
- Trial name
- NCT04393142
- Where
- Mexico
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez