Clinical trials: Hyperglycemia
Cystic Fibrosis, Glucose Metabolism Disorders
One Year Glargine Treatment in CFRD Children and Adolescents
Glargine treatment can improve the clinical features in Cystic Fibrosis patients affected by glucose derangements
- Trial name
- NCT00483769
- Testing
- Glargine
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Type 1 Diabetes
Continuous Subcutaneous Infusion of Pramlintide and Insulin
The purpose of this study is to see if giving the study drug in a slow and steady dose will lower blood sugars during the meal and after-meal time.
- Trial name
- NCT00291772
- Testing
- Pramlintide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Baylor College of Medicine
Hyperglycemia
The Therapeutic Effects of Insulin and Berberine on Stress Hyperglycemia
Berberine is a conventional component in Chinese medicine. In recent years, effects of Berberine on improvement of glucose metabolism have been explored.
- Trial name
- NCT02806999
- Testing
- Berberine; Insulin, Insulin
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Guangdong Provincial People's Hospital
Pancreatectomy; Hyperglycemia, Diabete Mellitus
Glucose Metabolism After Partial Pancreatectomy
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
- Trial name
- NCT04409171
- Testing
- oral glucose tolerance test
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Gestational Diabetes, Diabetes
The DNA Methylation of ARHGEF11 in Macrosomia
Background Macrosomia at birth is associated with subsequent susceptibility to obesity, abnormal glucose metabolism, hypertension and dyslipidaemia.
- Conditions
- Gestational Diabetes, Diabetes, Macrosomia, Fetal
- Trial name
- NCT03165643
- Testing
- OGTT
- Volunteers
- 239 people
- Sponsor
- Peking University First Hospital
Type 1 Diabetes
The Role of Amylin and Glucagon in T1DM
The purpose of this study is to see if giving pramlintide and insulin before a meal would lower high blood sugar and if a glucagon (a naturally made hormone in the body but reduced in diabetes and its role is in prevention of low…
- Trial name
- NCT00206258
- Testing
- Pramlintide and glucagon
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Hyperinsulinism, Diabetes
Bionic Pancreas in Children With Hyperinsulinism and Post-Pancreatectomy Diabetes
This is a pilot study designed to determine if the bihormonal bionic pancreas provides improved blood glucose control, compared to the current standard of care, in individuals with hyperinsulinism who developed diabetes after…
- Conditions
- Hyperinsulinism, Diabetes, Pancreatic Diseases, Pancreatectomy; Hyperglycemia
- Trial name
- NCT03303196
- Testing
- Bihormonal Bionic Pancreas
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Type 1 Diabetes (T1D), Pre Diabetes
INNODIA Family & Friends Early-Stage T1D Detection Protocol
The purpose of INNODIA DETECT is to identify people who are at increased risk of developing T1D. Investigators are doing this by testing for markers in the blood (autoantibodies) that tell them an individuals risk of getting T1D…
- Trial name
- INNODIA DETECT (NCT07118098)
- Where
- 21 sites in Austria, Belgium and 6 more
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- INNODIA iVZW
Shock, Preterm Birth Complication
Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial
The goal of this clinical trial is to determine the effectiveness of early use of hydrocortisone (since the diagnosis of shock) for its resolution within the first 72 hours in premature infants under 1,500 g.
- Conditions
- Shock, Preterm Birth Complication, Preterm Intraventricular Hemorrhage, Asphyxia Perinatal
- Trial name
- NCT07248761
- Testing
- Intravascular Hydrocortisone (stress dosage): 1 mg/k/dose each 8 hours for 5 days, Vasoactive drug therapies
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Nutrition, Pediatric Obesity
Metabolic and Genetic Impacts of Energy Drinks in Youth
Caffeine containing energy drinks (CCED) are beverages that typically contain mixtures of simple sugars, caffeine and may contain vitamin, mineral and/or herbal preparations.
- Conditions
- Nutrition, Pediatric Obesity, Pediatric, Caffeine
- Trial name
- NCT03512496
- Testing
- Acute energy drink - Caffein, Acute energy drink - Decaf
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Calgary
Impaired Glucose Tolerance, Prediabetes
CGM and Lifestyle Changes in Patients With Impaired Glucose Tolerance
The incidence of type 2 diabetes (T2D) in children is increasing, paralleling the rising incidence of obesity. Preventing children and adolescents from developing T2D is critical.
- Trial name
- NCT05387551
- Testing
- CGM
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nemours Children's Clinic
Type 1 Diabetes Mellitis, Cognition
Glycemic Control, Brain Structure and Cognition in Youth With Type 1 Diabetes (T1DM)
LO5 study: The investigators are inviting a new group of youth (ages 7-16) who have been recently diagnosed with type 1 diabetes and their non-diabetic siblings.
- Trial name
- LO5/HY5 (NCT00879203)
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hyperglycemia, Inflammation
Acute Effects of Postabsorptive and Postprandial Physical Activity
Physical activity performed in the postprandial state has the ability to blunt postprandial glycemia acutely, even as a result of very light or small amounts of postprandial physical activity.
- Trial name
- NCT02554669
- Testing
- postprandial and postabsorptive physical activity on treadmill
- Volunteers
- 12 people
- Sponsor
- Inland Norway University of Applied Sciences
Metabolic Syndrome X
Study of Chronic Degenerative Diseases
The prevalence of obesity and type 2 diabetes mellitus (DM) in children have been increasing in parallel at an alarming rate. In particular, the increasing prevalence of type 2 DM is attributable to genetic factors, clinical…
- Trial name
- NCT02495961
- Where
- Mexico
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Asociación Científica Latina A.C.
Screening for Hyperglycemia in First Trimester in High and Low Risk Pregnancy
Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy
Glucose intolerance is the commonest medical disorder complicating pregnancy. Hyperglycemia increases the risk of delivering a large for gestational age newborn (LGA) and related complications such as operative delivery, birth…
- Trial name
- NCT06064552
- Testing
- blood sugar
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Obesity, Morbid
GLP-1 Therapy for Weight Loss and Improved Glucose Tolerance in Obese Children
The prevalence of severely obese children is on the rise. Behavioral therapies for weight loss are successful in some, but others need more aggressive approaches such as drug therapy.
- Trial name
- NCT00886626
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Minnesota
Hyperglycaemia
Study of a Model-based Approach to Blood Glucose Control in Very-low-birthweight Neonates
Very low birthweight neonates commonly develop high blood sugar levels. There is an association between high blood sugar levels and poorer short term outcomes but it is not known whether the high sugar level itself actually…
- Trial name
- NCT01419873
- Testing
- Actrapid Human Insulin
- Where
- New Zealand
- Volunteers
- 30 people
- Sponsor
- Christchurch Women's Hospital
Pancreatitis, Chronic, Pancreatectomy; Hyperglycemia
A Prospective Observational Study of TPIAT
Multi-center, prospective, observational cohort study of patients undergoing total pancreatectomy with islet autotransplantation (TPIAT)
- Conditions
- Pancreatitis, Chronic, Pancreatectomy; Hyperglycemia, Pancreatitis
- Trial name
- POST (NCT03260387)
- Testing
- TPIAT
- Where
- 12 sites in United States
- Volunteers
- 433 people
- Sponsor
- University of Minnesota
Type 1 Diabetes, Hypoglycemia
Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 Diabetes
Type 1 diabetes (T1D) results from destruction of insulin producing beta cells by the body's own immune system (autoimmunity) causing an individual to lose the ability to make enough insulin to control their blood sugar levels…
- Trial name
- MUGGLE (NCT05616273)
- Testing
- Mixed Meal Tolerance Test (MMTT), Arginine Stimulation Test (AST), Home Finger Prick Sample
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- University of Exeter
Hyperprolactinemia, Weight Gain
Reversal of Antipsychotic-Induced Hyperprolactinemia, Weight Gain, Hyperglycemia and Dyslipidemia
This is a prospective, open-label study to evaluate the efficacy and safety in reducing antipsychotic-induced hyperprolactinemia, weight gain, and dyslipidemia by aripiprazole.
- Conditions
- Hyperprolactinemia, Weight Gain, Dyslipidemia
- Trial name
- NCT00541554
- Testing
- Abilify (aripiprazole)
- Sponsor
- Genovate Biotechnology Co., Ltd.,