Clinical trials: Hypothalamic Amenorrhea
Functional Hypothalamic Amenorrhea
The Research of Integrated Traditional Chinese and Western Medicine on Hypothalamic Amenorrhea
This study aims to validate the efficacy and safety of the "two-step cycle-regulating approach integrating Chinese and Western medicine: rapid restoration of menstruation with Western medicine, and nourish the kidney and soothe…
- Trial name
- NCT07580950
- Testing
- traditional Chinese medicine, Western medicine
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Peking Union Medical College Hospital
FHA (Functional Hypothalamic Amenorrhea)
Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea
The goal of this study is to determine whether romosozumab will improve bone density in girls and women with functional hypothalamic amenorrhea (cessation of the menstrual period due to intense exercise, stress, or an eating…
- Trial name
- NCT06533865
- Testing
- Romosozumab, Zoledronic acid
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- Massachusetts General Hospital
Growth Hormone Deficiency
Isolated Growth Hormone Deficiency and Amennorrhea
This is a case report of a 14-year old female with no menstruation history.
- Trial name
- NCT05448924
- Testing
- Hormone panel tests
- Where
- Indonesia
- Volunteers
- 1 people
- Sponsor
- Universitas Padjadjaran
Hypothalamic Amenorrhea, Functional
Assessment of Nutritional Knowledge, Habits, and Eating Behavior in Athletic Women to Evaluate the Possible Impact on Their Menstrual Function
The present study aims to investigate the degree of knowledge about nutrition and dietary habits in athletic women through validated questionnaires and to evaluate a possible impact on their menstrual function, including women…
- Trial name
- NCT06933888
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Bone Strength, Bone Density
Role of Estrogen on Skeletal Outcomes in FHA
The purpose of this study is to assess whether the natural form of estrogen (17-beta estradiol) given as a patch so that it is absorbed through your skin, is better at improving bone strength over 1 year than natural estrogen…
- Conditions
- Bone Strength, Bone Density, FHA (Functional Hypothalamic Amenorrhea)
- Trial name
- NCT07010146
- Testing
- transdermal 17β-E2 with cyclic progestin, oral 17β-E2 with cyclic progestin, transdermal EE+LNG
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
Primary Amenorrhoea, Hypothalamic Amenorrhoea
Pubertal Induction in Individuals With Hypogonadism
The investigators wish to explore the variability of uterine, breast and bone outcome markers as surrogates to assess the adequacy of exogenous oestrogen replacement in individuals with hypogonadism.
- Conditions
- Primary Amenorrhoea, Hypothalamic Amenorrhoea, Hypogonadotrophic Hypogonadism, Hypopituitarism
- Trial name
- NCT02871986
- Testing
- Routine transdermal oestrogen patch
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University College, London
Genetic Disorder, Infertility
Inherited Reproductive Disorders
Background: During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. Some people have low hormone levels that severely delay or prevent puberty.
- Conditions
- Genetic Disorder, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01500447
- Where
- 2 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Hypogonadotropic Hypogonadism, Amenorrhea
Pulsatile GnRH in Anovulatory Infertility
The purpose of this study is to explore the effects of synthetic gonadotropin-releasing hormone (GnRH) upon the pituitary and ovaries of women with infertility.
- Conditions
- Hypogonadotropic Hypogonadism, Amenorrhea, Kallmann's Syndrome
- Trial name
- NCT00383656
- Testing
- GnRH, Pump
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Massachusetts General Hospital
Amenorrhea Secondary
AMH and Functional Hypothalamic Amenorrhea
The purpose of this study is to analyze AMH levels in patients with prolonged FHA (more than 2 years). Based on previous studies, we can assume that prolonged FHA may mimic a condition of primary hypogonadotropic hypogonadism…
- Trial name
- AMELIA (NCT05921877)
- Testing
- venous sampling
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Amenorrhea, Hypogonadotropic Hypogonadism
Baselines in Reproductive Disorders
The purpose of the study is to explore the way in which gonadotropins (pituitary hormones) are released into the body. The knowledge acquired in this study will be used for the diagnosis and treatment of reproductive endocrine…
- Conditions
- Amenorrhea, Hypogonadotropic Hypogonadism, Kallmann's Syndrome
- Trial name
- NCT00456274
- Testing
- Frequent baseline blood sampling
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Massachusetts General Hospital
Hypogonadism, Hypergonadism
Observation of Environment and Reproductive-Endocrine Effects
Background: Endocrine disorders occur when the glands that make hormones do not work properly. Hormones levels that are too high or too low can cause problems such as late or early puberty, irregular periods, and infertility.
- Conditions
- Hypogonadism, Hypergonadism, Precocious Puberty, Late Puberty
- Trial name
- NCT06280807
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Kallmann Syndrome, Hypogonadotropic Hypogonadism
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate
The purpose of this study is to explore the genetic basis of reproductive disorders and cleft lip and/or palate.
- Conditions
- Kallmann Syndrome, Hypogonadotropic Hypogonadism, Hypothalamic Amenorrhea, Polycystic Ovarian Syndrome
- Trial name
- NCT01601171
- Where
- Switzerland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois