Clinical trials: IDDM
Diabetes Type 1
Insul-In This Together: Leveraging Family Support and Diabetes Technology for Adolescents Living With Type 1 Diabetes
The goal of this clinical trial is to learn if the "Insul-In This Together" family program works to improve outcomes for adolescents living with type 1 diabetes.
- Trial name
- IITT (NCT07856836)
- Testing
- Insul-In This Together
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Type 1 Diabetes Mellitus
Type 1 Diabetes Data Acquisition and Transfer Adherence Study
The purpose of this pilot study is to determine if training and support, combined with reminders to facilitate glucose data sharing with the diabetes care team in between clinic visits, can improve glycemic outcomes for patients…
- Trial name
- T1D-DATA (NCT03228004)
- Testing
- Glooko MeterSync
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Florida
Diabetes, Diabetes Mellitus, Type 1
An Observational Study to Assess Safety and Effectiveness of Intravenous NovoRapid® in Hospitalised Subjects
This study is conducted in Asia. The aim of this observational study is to evaluate the side effects profile and benefits of using intravenous insulin aspart infusion in hospitalised subjects under normal clinical practice…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00700648
- Testing
- insulin aspart
- Where
- India
- Volunteers
- 3,024 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 1, Diabetic Ketoacidosis
Early Administration of Long-acting Insulin Treatment of Diabetic Ketoacidosis in Pediatric Type 1 Diabetes
The management goals of diabetic ketoacidosis (DKA) in the pediatric type 1 diabetes (T1DM) population are fluid and electrolyte repletion, insulin administration, and correction of acidosis in order to stabilize the patient.
- Trial name
- NCT02548494
- Testing
- Glargine, IV insulin, Electrolyte Correction
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Chattanooga-Hamilton County Hospital Authority
Type 1 Diabetes Mellitus
PRISM for Adolescents With Type 1 Diabetes
It is well-known that adolescents with type 1 diabetes are at high risk for elevated diabetes-specific distress and poor glycemic control.
- Trial name
- NCT03847194
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- Seattle Children's Hospital
Type 1 Diabetes, Hypoglycemia
Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 Diabetes
Type 1 diabetes (T1D) results from destruction of insulin producing beta cells by the body's own immune system (autoimmunity) causing an individual to lose the ability to make enough insulin to control their blood sugar levels…
- Trial name
- MUGGLE (NCT05616273)
- Testing
- Mixed Meal Tolerance Test (MMTT), Arginine Stimulation Test (AST), Home Finger Prick Sample
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- University of Exeter
Type 1 Diabetes
Screening For Social Determinants Of Health In Routine Diabetes Care
Social determinants of health (SDOH) exert a powerful influence on the everyday management of type 1 diabetes (T1D) and short and long term outcomes of T1D.
- Trial name
- SDOH (NCT07706803)
- Testing
- Social Determinants of Health (SDOH) Screening and Referral
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Type 1 Diabetes
Cohort Study of Patients With Type 1 Diabetes Registered With Mobile Application in China
For last decade, the innovation of mobile health platform has brought new opportunities for disease management. Previous studies have shown that health management programs based on mobile platforms for patients with diabetes can…
- Trial name
- COOPERATIONS (NCT05163054)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University Third Hospital
Type 1 Diabetes Mellitus
T Cell Validation Study Using Blood Samples From Subjects With Recent Onset Type 1 Diabetes Mellitus
Type 1 diabetes is a condition that is caused in part by an abnormality of the immune system which occurs when T cells, which are part of the immune system, damage the insulin secreting cells (islet cells) in the pancreas.
- Trial name
- NCT00212329
- Testing
- T Cell Proliferation and Autoreactivity Assays, Cellular Immunoblot Assays, Tetramer Studies
- Where
- 14 sites in United States, United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes
Study of Offspring of Women With Type 1 Diabetes
There is an increasing trend in the society for developing obesity, type 2 diabetes and cardiovascular diseases. It is therefore important to identify the risk factors behind this tendency.
- Trial name
- EPICOM (NCT01559181)
- Where
- 3 sites in Denmark
- Volunteers
- 584 people
- Sponsor
- Odense University Hospital
Type 1 Diabetes
School Centered Telemedicine Program for Children With Type 1 Diabetes Mellitus
The purpose of this study is to determine if using school-based telemedicine for diabetes support and education in students with type 1 diabetes in grades K-8 can lead to improvement in control of diabetes and improved…
- Trial name
- NCT00566475
- Testing
- telemedicine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- State University of New York - Upstate Medical University
CTLA4 Haploinsufficiency
Neurologic and Immunologic Characteristics of CTLA-4 and LRBA Hereditary Deficiency
CTLA4 and LRBA deficiencies are rare genetic disorders, recently described, and associated with multiple clinical features. It ranges from recurrent infections, auto-immunity, and organ infiltration with lymphocytes.
- Trial name
- NCT05040256
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Diabetes Mellitus, Type 1
AbATE Follow-Up Study
This study proposes to conduct a non-interventional, multi-center trial that will look at C-peptide results from one or two Mixed Meal Tolerance Tests (MMTT) in participants who received anti-CD3 treatment or placebo on the Abate…
- Trial name
- NCT02067923
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Diabetes Mellitus, Type 1
Exercises on Children and Adolescents With Type 1 Diabetes Mellitus (T1DM)
This study aimed to assess the effect of aerobic and resistance exercise on postprandial blood glucose levels in children and adolescents aged 10 - 18 years, diagnosed with type 1 diabetes mellitus (T1DM) for at least 1 year…
- Trial name
- NCT06680557
- Testing
- Aerobic and resistance exercises
- Where
- Egypt
- Volunteers
- 49 people
- Sponsor
- Sohag University
Diabetes Mellitus, Type 1
Cardiac Dysfunction in Adolescents With Type 1 Diabetes: Contribution of Daily-life Glucoregulation and Impact on Cardiorespiratory Exercise Capacity
During the course of type 1 diabetes mellitus (T1DM), several complications can occur. One of these is the development of diastolic and systolic dysfunction (even in the absence of ischemic, valvular or hypertensive heart…
- Trial name
- GIIADMT1 (NCT04052919)
- Testing
- Cardiac dysfunction in adolescents with type 1 diabetes
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Hasselt University
Type 1 Diabetes
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
This is a Phase 2b, investigator- and participant-blinded, placebo-controlled, parallel-arm study to evaluate the efficacy, safety and tolerability of SAB 142 in patients with Stage 3 New Onset of Type 1 Diabetes (NOT1D).
- Trial name
- SAFEGUARD (NCT07187531)
- Testing
- High Dose SAB-142, Low Dose SAB-142
- Where
- 68 sites in United States, Australia and 13 more
- Volunteers
- 159 people
- Sponsor
- SAb Biotherapeutics, Inc.
Type 1 Diabetes Mellitus
Omnipod Horizon™ Automated Glucose Control System Preschool Cohort
Subjects will undergo a 14-day outpatient, standard therapy phase during which sensor and insulin data will be collected. This will be followed by a 94-day (13-week) hybrid closed-loop phase conducted in an outpatient setting…
- Trial name
- NCT04476472
- Testing
- Omnipod Horizon™ Automated Glucose Control System
- Where
- 10 sites in United States
- Volunteers
- 80 people
- Sponsor
- Insulet Corporation
Diabetes Mellitus, Type 1
Assessment of an Automatic Closed-loop Insulin Delivery System
The overall aim of this research proposal is to determine the safety, feasibility and efficacy of an automatic closed-loop insulin delivery system.
- Trial name
- NCT02366767
- Testing
- Automatic closed-loop insulin delivery, Control
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Stanford University
Type 1 Diabetes
COVID-19 Pandemic Lockdown Effect in Adolescents and Young Adults With Type 1 Diabetes: Positive Results of an Unpreceded Challenge for Telemedicine and Patient Self-management
Lockdown resulting from the COVID-19 pandemic was an unpreceded model of the impact of lifestyle on chronic diseases, especially for adolescents and young adults with type 1 diabetes (T1D) whose lifestyle is known to strongly…
- Trial name
- COVIDIABADO (NCT04669912)
- Testing
- glucose control and sensor usage
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Sud Francilien
Nurse's Role
Nurse-led Therapeutic Education Effects in Glycemic Control and Knowledge of Type 1 Diabetes Mellitus Patients Under Hospital Transition
The goal of this interventional quasiexperimental study is to learn about the influence of therapeutic education carried out by nurses in the management and knowledge of patients with T1DM.
- Trial name
- NCT05766215
- Testing
- Therapeutic Education
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
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