Clinical trials: INTENSIVE CARE
ICU Acquired Weakness
Development of an Early Warning Model for Intensive Care Unit-Acquired Weakness in Mechanically Ventilated Children
Acquired weakness (AW) is a common complication among patients in the Intensive Care Unit (ICU). It is a systemic muscle weakness and dysfunction associated with critical illness, often related to prolonged bed rest, mechanical…
- Trial name
- NCT07150637
- Testing
- ICU-AW
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Children's Hospital of Fudan University
Thrombocytopenia, Neonatal Thrombocytopenia
Neonatal Thrombocytopenia in the NICU
This prospective cohort study aims to determine the frequency, severity, and clinical outcome of thrombocytopenia among neonates admitted to the neonatal intensive care unit.
- Trial name
- NCT07882342
- Volunteers
- 120 people
- Sponsor
- Assiut University
Infant, Premature, Diseases
Safe Passages: Ensuring Quality Transitions From NICU (Neonatal Intensive Care Unit) to Ambulatory Care
Infants born prematurely or with complex congenital abnormalities are surviving to discharge in growing numbers and often require significant monitoring and coordination of care in the ambulatory setting.
- Trial name
- NCT01088945
- Testing
- Enhanced Discharge process
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Virginia Moyer
Infants in Neonatal Intensive Care Units
Improving Antimicrobial Prescribing Practices in the Neonatal ICU
To determine if 3 randomly assigned bundles of stewardship interventions would reduce overall and inappropriate antimicrobial use in the neonatal intensive care unit (NICU), a pre-post study was performed in 4 NICUs.
- Trial name
- iNAP (NCT03079245)
- Testing
- Education Plus (E+), Clinical Decision Support, Prescriber Audit and Feedback
- Where
- 4 sites in United States
- Volunteers
- 6,184 people
- Sponsor
- Columbia University
Invasive Fungal Infections
Survey on the Current Status of IFD Diagnosis and Treatment by Intensive Care Physicians in Sichuan Province (IFS)
The goal of this survey is to learn about the current status of the diagnosis and treatment of invasive fungal infections among intensive care physicians in Sichuan Province (IFS).
- Trial name
- IFS (NCT06346951)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
ICU Sedation
Safety, Tolerability and Efficacy of DEXDOR in Pediatric Patients in ICU
Open clinical trial to evaluate safety, tolerability, and efficacy of Dexdor for sedation in paediatric patients in intensive care settings. Multi-centre trial in Russia for marketing registration of Dexdor
- Trial name
- Pedrux (NCT03813277)
- Testing
- Dexmedetomidine
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Orion Corporation, Orion Pharma
Sepsis, Cancer, Heart Attack, Heart Failure, Abdominal Surgery, Trauma, Diabetes, Lung Disease, Gynaecology, Fertility, Cardiac Surgery,
Medical Record Study on Adverse Events Requiring a Higher Level of Care in Flemish Hospitals
An adverse event (AE) is defined as unintended injury or complication, which results in disability, death or prolongation of hospital stay, and is caused by healthcare management (including omissions) rather than the patient's…
- Trial name
- NCT02044718
- Where
- Belgium
- Volunteers
- 878 people
- Sponsor
- Hasselt University
Motor Skills Disorders
Profile of Newborn Undergoing Early Stimulation in a Neonatal Intensive Care Unit
To describe the profile of newborns undergoing early stimulation in a neonatal intensive care unit, characterizing the study population, according to its variables and neonatal risk factors, indications for treatment of early…
- Trial name
- NCT01660178
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Pediatric Intensive Care Units
A Korean Point Prevalence Study of Acute Rehabilitation for Kids in the PICU (PARK-PICU)
This study investigates the prevalence of acute rehabilitation practices among children in pediatric intensive care units (PICUs).
- Trial name
- NCT07629297
- Testing
- Acute Rehabilitation (Observed Practice)
- Where
- 13 sites in South Korea
- Volunteers
- 396 people
- Sponsor
- Samsung Medical Center
Pediatric Intensive Care Unit, Comfort
Comfort Intervention in PICU Children
This randomized controlled trial evaluates a family-centered comfort intervention for children hospitalized in a pediatric intensive care unit.
- Conditions
- Pediatric Intensive Care Unit, Comfort, Anxiety in Children, Fear
- Trial name
- CCI-PICU (NCT07441668)
- Testing
- Intervention Family-Centered Comfort, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Medication Errors and Other Product Use Errors and Issues, Adverse Drug Event
Reducing Errors In The Neonatal Intensive Care Unit
This is a monocentric prospective pre and post-intervention study, aiming at analyzing the efficacy of the Computerized Provider Order Entry (CPOE) plus Bar Code Medication Administration (BCMA) as compared to paper order entry…
- Trial name
- SAPHET-i (NCT04193839)
- Testing
- Computerized Provider Order Entry (CPOE) plus Bar Code Medication Administration (BCMA)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Thrombocytopenia
Assessment of Risk Factors and Outcome of Thrombocytopenia in ICU Patients
The many comorbidities in the severely ill patient also make thrombocytopenia very common (∼ 40%) in intensive care unit patients.
- Trial name
- NCT05958511
- Volunteers
- 130 people
- Sponsor
- Assiut University
Contrast Induced Nephropathy
Contrast Agent-associated Nephrotoxicity in Intensive Care Unit Patients
The use of N-acetylcysteine and ascorbic acid reduce the incidence of radiographic contrast agent induced reduction in renal function in Intensive Care Unit patients.
- Trial name
- ICU (NCT01017796)
- Testing
- N-acetylcysteine and ascorbic acid
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Cardiac Arrest
NEUROlogical Prognosis After Cardiac Arrest in Kids
Each year around 2000 children have a cardiac arrest in the United Kingdom (UK) and approximately one fifth are admitted to Pediatric Intensive Care Unit.
- Trial name
- NEUROPACK (NCT03574025)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Birmingham
Infection, Sepsis
Short-course Antimicrobial Therapy in Sepsis
The purpose of this study is to compare the effect of a short course antimicrobial therapy (5-days) versus a 10-days therapy on sepsis-related organ dysfunction.
- Conditions
- Infection, Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT02899143
- Testing
- Antibiotic
- Where
- 4 sites in Italy
- Volunteers
- 320 people
- Sponsor
- Ospedale Santa Maria delle Croci
Behavioral Assessment of Children, Early Intervention
PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)
Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed…
- Trial name
- PREPARE (NCT04783220)
- Testing
- Comprehensive structured parent intervention
- Where
- Lebanon
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Interprofessional Relations, Interprofessional Education
Interprofessional Collaboration in the Cardiac Intensive Care Unit (CICU): An Action-Research Training Project
This study evaluates the impact of a structured interprofessional training program on daily collaboration within the Cardiac Intensive Care Unit (CICU/UTIC) at the University Hospital of Parma.
- Conditions
- Interprofessional Relations, Interprofessional Education, Attitude of Health Personnel, Intensive Care Units
- Trial name
- COLLUTIC_25 (NCT07360366)
- Testing
- The training phase of the project consists of an interactive course aimed at healthcare professionals (physicians, nurses and OSS) to improve their ability to recognise and enact effective collaborati
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Bacterial Infections
Direct Molecular Characterization of Bacteria From ICU and From the REHAB
Investigators aim to directly investigate the molecular properties of bacteria from tracheal and urinary samples routinely taken in intensive care units (ICU) patients.
- Trial name
- NCT03475472
- Where
- 2 sites in Switzerland
- Volunteers
- 971 people
- Sponsor
- University Hospital, Basel, Switzerland
Communication
Improving Communication in the PICU: The Navigate Study
The project seeks to study the use of an navigator-based intervention called "PICU Supports." The study will test the impact of PICU Supports during and after PICU discharge on parent outcomes (satisfaction with decision making…
- Trial name
- NCT02333396
- Testing
- PICU Supports, Educational Brochure
- Where
- 2 sites in United States
- Volunteers
- 442 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Preterm Infant, Infant, Premature
Pilot Study of the SENSITIVE Care Program for Preterm Infants in the Neonatal Intensive Care Unit
The goal of this clinical trial is to learn whether the Sensory Integrative Intervention (SENSITIVE) Care Program helps reduce stress and improve mother-infant interaction in preterm infants receiving care in the Neonatal…
- Conditions
- Preterm Infant, Infant, Premature, Neonatal Intensive Care Unit (NICU)
- Trial name
- SENSITIVE Care (NCT07728760)
- Testing
- SENSITIVE Care Program, Standard Neonatal Intensive Care
- Where
- Indonesia
- Volunteers
- 8 people
- Sponsor
- Gadjah Mada University