Clinical trials: Identify
Balanced Chromosomal Translocation
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations
For every child with developmental delay, the investigators do a constitutional karyotype. This karyotype can reveal an apparently balanced chromosomal rearrangement (no visible loss or gain of genetic material), such as a…
- Trial name
- NCT01826708
- Testing
- Identification of breakpoints
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Oncology Patients
Issues and Challenges in Cancer Patients on Active Treatment During the COVID-19 Pandemic
In view of increasing cases of SARS-CoV-2 leading to the COVID-19 Pandemic in India,there has been unprecedented restrictions on travel, work and other aspects of daily life.
- Trial name
- NCT04406844
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Max Healthcare Insititute Limited
SARS-CoV Infection
A Feasibility Study Using the CoronaCheck Device to Identify Incident Cases of SARS CoV-2 Covid-19
Point of care testing is urgently required to enable the immediate detection of SARS-CoV-2 infection to allow effective transmission prevention precautions to succeed.
- Trial name
- NCT04742712
- Testing
- CoronaCheck Device
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Milk and/or Peanut Allergy
Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic Dermatitis
Background: Atopic dermatitis (AD), also called eczema, makes skin dry, red, and itchy. People with AD are more likely to get a food allergy than people without AD.
- Trial name
- NCT03835767
- Testing
- Peanut powder and Oat flour
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gynaecological, Urological or Rectal Cancer
Prospective Study in Pelvic Radiotherapy Patients
Symptoms such as diarrhoea and abdominal discomfort are common side effects of radiotherapy for tumours in the pelvis and usually occur within 2 weeks of starting treatment.
- Trial name
- NCT00220181
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Congenital Talipes Equino Varus
Gait Analysis in Idiopathic Clubfoot Patients Treated by the Ponseti Method
The purpose of this study is to assess the walking pattern of clubfoot patients using a pressure sensing walkway, and investigate whether any of the data produced can be used to detect the early signs of relapse in their foot…
- Trial name
- NCT05572411
- Testing
- GAITRite Electronic Walkway
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Lower Respiratory Tract Infection
Recovery Time in Children With Lower Respiratory Tract Infections Treated With Klacid® Granules for Oral Suspension.
Klacid Granules for Oral Suspension provides short symptoms' recovery time in Thai children with lower respiratory tract infections.
- Trial name
- NCT01076166
- Testing
- clarithromycin (Klacid) granules for oral suspension
- Where
- 16 sites in Thailand
- Volunteers
- 337 people
- Sponsor
- Abbott
Breast Cancer
Diagnostic Study to Identify Sentinel Lymph Nodes in Women With Stage I or Stage II Breast Cancer
RATIONALE: Diagnostic procedures, such as blue dye or imaging to identify sentinel lymph nodes, may improve the ability to detect the extent of disease and help plan effective surgery for removing breast tumors.
- Trial name
- NCT00003654
- Testing
- patent blue V dye, lymphangiography, radionuclide imaging
- Where
- France
- Volunteers
- 200 people
- Sponsor
- UNICANCER
Neutropenia, Fever
Use of NGS Cell-free Pathogen Test for Identification of Low Risk Fever & Neutropenia in Pediatric Patients
Febrile neutropenia is a common complication in pediatric oncology patients. Standard of care requires admission of all patients for intravenous antibiotics until cultures are negative, patients are afebrile and there are signs…
- Trial name
- NCT03530072
- Testing
- Karius Test
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Karius, Inc.
Healthy Lifestyle
Connect-5 Needs Assessment Survey to Identify Healthy Lifestyle Requirements of a Rural Irish Community
This is an anonymous needs assessment survey of the population of an Irish urban town. We plan to collect anonymous survey data in order to better understand residents needs and to determine the desired functionality of a new…
- Trial name
- CONNECT-5 (NCT05109026)
- Where
- Ireland
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Autism Spectrum Disorders
The Development of Younger Siblings of Children With Autism Now at 10 Years of Age
Background: Autism is a complex developmental disorder involving difficulties in verbal and nonverbal communication, social-emotional functioning, and markedly restricted interests and activities.
- Trial name
- NCT00695812
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
COVID-19
Retrospective Study for Identificatiopn of a Link Between Doxycycline and COVID-19 Treatment
A new coronavirus, the third documented animal-to-human passage, emerged in Wuhan , China in the last quarter of 2019. Acne patients on doxycycline escaped seasonal viruses, showing the interest of this antibiotic as a possible…
- Trial name
- DOXY-COVID (NCT05445479)
- Testing
- Doxycycline
- Sponsor
- Nantes University Hospital
Asthma
The Use of FKBP51 in the Identification of Non-adherence to Inhaled Corticosteroids in Difficult Asthma
Approximately 5-10% of people with asthma do not respond to to standard therapy and are referred to as having difficult asthma. Evidence shows that this poor response is not always related to asthma severity and non-adherence to…
- Trial name
- NCT01526707
- Testing
- inhaled steroid
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Liam Heaney
Childhood Obesity
Whole-exome Sequencing in Childhood Obesity
Obesity is a complex multifactorial disease where genetics play an important role in predisposing children to early onset obesity.
- Trial name
- NCT02418377
- Where
- 2 sites in Singapore
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Preterm Birth, Premature Rupture of Membranes
Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition
The understanding of the biological mechanisms underlying preterm birth is very limited, making prevention of preterm birth difficult.
- Trial name
- NCT00342277
- Where
- 4 sites in United States, Chile and 2 more
- Volunteers
- 6,838 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Down Syndrome, Obstructive Sleep Apnea
Using Personal Mobile Technology to Identify Obstructive Sleep Apnea in Children With Down Syndrome (UPLOAD)
This study aims to see if mobile video clips (smartphone recordings) can be used to screen children with Down syndrome to identify those at highest risk of obstructive sleep apnea (OSA), so they can be prioritized for an earlier…
- Conditions
- Down Syndrome, Obstructive Sleep Apnea, Child
- Trial name
- UPLOAD (NCT04022460)
- Testing
- Video clip assessment, Polysomnography (sleep study), Educational webinar
- Where
- Canada
- Volunteers
- 141 people
- Sponsor
- Children's Hospital of Eastern Ontario
Pulmonary Infection
Massively Parallel Sequencing to Identify Microbiological Organisms in Bronchoalveolar Lavage Fluid
Patients who are post hematopoietic stem cell transplantation who require a bronchoalveolar lavage (BAL) for standard clinical car will have extra fluid collected and sent for massively parallel sequencing to see if it is as…
- Trial name
- NCT03995030
- Testing
- massively paralleled sequencing
- Volunteers
- 10 people
- Sponsor
- New York Medical College
Crohn Disease
Non-invasive Approaches to Identify the Cause of Fatigue in Inflammatory Bowel Disease Patients.
Crohn's disease (CD) presents with severe symptoms, but fatigue is a very predominant symptom that negatively impacts upon quality of life.
- Trial name
- IBD Fatigue (NCT03670693)
- Testing
- Muscle strength and fatigue assessment, Dual-energy X-ray absorptiometry (DEXA scan), Supine cardiorespiratory fitness assessment
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Heart Failure, Diabetes
Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes
A pragmatic electronic health record (EHR) based randomized controlled trial to evaluate the utility of providing Ultromics EchoGo analysis results and recommendations for HF risk prevention therapies using an EHR embedded…
- Trial name
- NCT06593314
- Testing
- Message with EchoGo, Standard Message
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Texas Southwestern Medical Center
Neonatal Encephalopathy
Remote EEG Device for Identification of Risk for Neonatal Seizures
The purpose of this study is to see if the use of wireless brain wave monitoring can be helpful for newborns and help their medical providers identify seizures earlier and to monitor for the risk for seizures.
- Trial name
- NCT05239585
- Testing
- Epilog device
- Where
- United States
- Sponsor
- Mayo Clinic