Clinical trials: Imaging Evaluation
Alzheimer's Disease, Hippocampus
Using Neuroimaging to Early Diagnose Alzheimer's Disease Through Hippocampal Atrophy Assessment
This study aims to better understand Alzheimer's disease by looking at brain scans, specifically MRI images, to detect early signs of brain changes linked to the disease.
- Conditions
- Alzheimer's Disease, Hippocampus, Brain Atrophy, Magnetic Resonance Imaging
- Trial name
- NCT06965816
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Saint-Denis
Osteoarthritis Knee
Effectivity of Allogenic Umbilical Cord Mesenchymal Stem Cells Conditioned Media for Osteoarthritis of the Knee Joint
Osteoarthritis (OA) is a joint disorder that often occurs and causes disability. This disorder is characterized by an inflammatory reaction in the synovial joints accompanied by a gradual degeneration process in the articular…
- Trial name
- NCT06688318
- Testing
- Intra-articular secretome injection therapy
- Where
- Indonesia
- Volunteers
- 11 people
- Sponsor
- Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia
Atherosclerosis, Carotid Atherosclerosis
Visualization of Carotid Atherosclerosis by 68Ga-MSA
Until now, no specific atherosclerosis-targeting agent labeled with positron emitter is not yet available. Investigators developed neomannosyl human serum albumin(MSA) for the terminal mannose residues of MSA binding with the…
- Conditions
- Atherosclerosis, Carotid Atherosclerosis, Noninvasive Imaging of Atherosclerosis
- Trial name
- NCT01893489
- Testing
- 68Gallium-MSA
- Where
- 2 sites in South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Korea University
Adolescent Idiopathic Scoliosis
3D Depth Camera-Based Assessment of Adolescent Idiopathic ScoliosisUsing a Depth Camera
Adolescent Idiopathic Scoliosis (AIS) is a common spinal deformity affecting adolescent health, and early diagnosis and accurate assessment are crucial for preventing disease progression.
- Trial name
- NCT06717568
- Testing
- no intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Simultaneous Pancreas-Kidney Transplantation
To Explore the Value of Magnetic Resonance Imaging in Noninvasive Quantitative Evaluation of Graft Function After Simultaneous Pancreas-kidney Transplantation
Pancreatic kidney joint transplantation (SPK) has become the standard treatment for patients with diabetes complicated by end-stage renal disease.
- Trial name
- NCT07001917
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhen Li
Leptomeningeal Metastasis, Leptomeningeal Disease
A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide
The FORESEE Study is a multi-center, prospective clinical trial enrolling patients with Breast or Non-Small Cell Lung Cancer (NSCLC) who have suspicious or confirmed Leptomeningeal Metastases (LM).
- Conditions
- Leptomeningeal Metastasis, Leptomeningeal Disease, Leptomeningeal Neoplasms, Breast Cancer
- Trial name
- FORESEE (NCT05414123)
- Testing
- CNSide
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Biocept, Inc.
Ovarian Cancer
Early Assessment of Ovarian Cancer Aggressiveness by Metabolic Imaging
To learn if an MRSI can be performed on a 3T scanner using an investigational contrast drug called hyperpolarized 13-C pyruvate. 3T refers to the "strength" of the MRI machine.
- Trial name
- NCT05866679
- Testing
- Hyperpolarized 13-C-pyruvate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Spinal Neoplasms
Evaluation of Effectiveness of CyberKnife Stereotactic Radiosurgery for Spinal Tumors
This study aims to explore the reliability of the combination of functional magnetic resonance imaging and radiomics for evaluation of the therapeutic efficacy of CyberKnife stereotactic radiosurgery for spinal tumors.
- Trial name
- NCT04192383
- Testing
- Cyberknife stereotactic radiosurgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Motility Disorder of Intestine
Magnetic Resonance Imaging Assessment of Small Bowel Motility
This project involves the development, validation and application of a novel test using MRI to assess gastrointestinal motility a vital process that mixes the contents of our digestive tract.
- Trial name
- NCT02754869
- Where
- United Kingdom
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University College, London
Von Hippel-Lindau Disease
Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease
Von Hippel-Lindau disease (VHL) is an inherited cancer syndrome. Patients are at risk for developing pancreatic cysts and tumors. These tumors are more aggressive in some people than in others.
- Trial name
- NCT00062166
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Cancer Institute (NCI)
White Spot Lesions, Proximal Caries
Labial White Spot Lesions and Proximal Caries Development in Orthodontic Patients Using Clear Aligners Versus Traditional Braces.
This randomized clinical trial evaluates the risk of developing early tooth decay in patients undergoing orthodontic treatment with either traditional fixed braces or clear aligners.
- Conditions
- White Spot Lesions, Proximal Caries, Oral Hygiene in Orthodontic Patients, Plaque Removal
- Trial name
- NCT07550179
- Testing
- Fixed pre-adjusted edgewise orthodontic appliance, Clear aligner therapy
- Where
- United Arab Emirates
- Volunteers
- 24 people
- Sponsor
- University of Sharjah
Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction
Feasibility of Non-invasive Hemodynamic Assessment by 5D Flow in Congenital Heart Disease
This study evaluates whether new flow parameters of the cardiac magnetic resonance imaging (MRI) allow evaluation of parameters for which usually invasive rigth-left heart catheterization are necessary.
- Conditions
- Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction, Fontan Circulation
- Trial name
- NCT07742046
- Testing
- Right-left heart catheterization in magnetic resonance imaging (MRI)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Tobias Rutz
Port-wine Stain
Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment
Port-wine stain is a congenital, progressive vascular malformation of human skin involving post-capillary venules that occurs in an estimated 0.3% of children and can alter personality development and psychological in children.
- Trial name
- NCT01774552
- Testing
- Photo Acoustic Microscopy and Optical Coherence tomography
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Bipolar Disorder
Clinical Trial of Pramipexole in Bipolar Depression
The purpose of this study is to examine the safety and effectiveness of the drug pramipexole given in combination with lithium or divalproex for the short-term treatment of acute depression in patients with bipolar disorder.
- Trial name
- NCT00025792
- Testing
- Pramipexole
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Bone Metastases, Castrate-resistant Prostate Cancer
Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer
This study is being done to help researchers understand more about prostate cancer that has spread to the bones by using the newest magnetic resonance imaging (MRI) techniques and to better understand the effect of an…
- Conditions
- Bone Metastases, Castrate-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage IV Prostate Cancer
- Trial name
- NCT01599793
- Testing
- cabozantinib, laboratory biomarker analysis, magnetic resonance imaging
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Chicago
Maxillary Sinus, Cone-Beam Computed Tomography
Anatomical and Imaging Assessment of the Alveolar Antral Artery Canal Using CBCT
This research project aims to improve understanding of the alveolar antral artery canal, an anatomical structure located in the maxilla, using cone-beam computed tomography (CBCT).
- Conditions
- Maxillary Sinus, Cone-Beam Computed Tomography, Artery
- Trial name
- NCT07726121
- Testing
- Assigned Interventions
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Breast Cancer Female
The Role of Magnetic Resonance Imaging in Assessment of Axillary Lymph Nodes Metastasis in Breast Cancer Patients.
Breast cancer is the most common cancer among women worldwide.The main cause of cancer related death is the invasion and metastasis. The usual site of spread outside the breast is to lymph nodes in the axilla.
- Trial name
- NCT03163316
- Testing
- Unenhanced magnetic resonance imaging.
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Chronic Venous Disease
Mobile Phone Thermal Imaging Assessment of Incompetent Perforator Veins
Chronic venous disease is a common disease of the lower limbs. Severe CVD can lead to lower limb swelling, pigmentation, and repeated skin ulceration, which seriously affects patients' quality of life.
- Trial name
- NCT06834555
- Testing
- Mobile phone thermal imaging
- Volunteers
- 100 people
- Sponsor
- Guangdong Second Provincial General Hospital
Consciousness Disorders, Persistent Vegetative State
Multimodal Assessment and Prognosis in Disorders of Consciousness After Severe Brain Injury (CyDoC-MAP)
After a severe brain injury some patients survive but cannot communicate, and deciding early which of them are likely to recover consciousness remains one of the hardest problems in neurocritical care.
- Conditions
- Consciousness Disorders, Persistent Vegetative State, Unresponsive Wakefulness Syndrome, Minimally Conscious State
- Trial name
- CyDoC-MAP (NCT07736820)
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Nicosia General Hospital
Breast Cancer
Assessment of Cardiotoxicity After Chemotherapy for Breast Cancer by Cardio-vascular Magnetic Resonance (MR)
Consecutive patients with a first diagnosis of breast cancer will be identified at the Tom Baker Cancer Centre (TBCC) and included into the study, if they are going to receive chemotherapy with anthracyclines and / or Trastuzumab…
- Trial name
- Cardiotox (NCT00679874)
- Testing
- Cardio-vascular MRI
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Calgary