Clinical trials: Implementation
Childhood Pneumonia, Hypoxemia
Assessing the Feasibility and Effectiveness of Introducing Pulse Oximetry in IMCI Services
The purpose of the study is to assess the feasibility, acceptability and operational challenges of introducing Pulse Oximeter (PO) in IMCI services to manage acute respiratory infections at first-level primary care facilities in…
- Trial name
- NCT03750747
- Testing
- Pulse Oximeter
- Where
- Bangladesh
- Volunteers
- 612 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Drive, Adolescent Behavior
Translation Study of a Safe Teen Driving Intervention
Steering Teens Safe (STS) is an evidence-based and parent-focused intervention developed by the investigators, which aims to improve safe teen driving practices by enhancing parental communication skills.
- Conditions
- Drive, Adolescent Behavior, Risk Behavior
- Trial name
- NCT04317547
- Testing
- Steering Teens Safe (STS), Driving Feedback Technology.
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ginger Yang
HIV
HIV Testing at Family Planning Clinics in Mombasa County, Kenya
Location: Family Planning Clinics in Mombasa County, Kenya Introduction: Integration of HIV treatment and prevention with family planning (FP) services is a promising approach for optimizing delivery of comprehensive healthcare…
- Trial name
- NCT02994355
- Testing
- Systems Analysis and Improvement Approach
- Where
- 24 sites in Kenya
- Volunteers
- 24 people
- Sponsor
- University of Washington
Developmental Language Disorder, Reading; Difficult
Promoting Caregiver Implementation of an Effective Early Learning Intervention
The goal of this study is to examine the impact of a caregiver-implemented shared reading program, Sit Together and Read (STAR), on children ages 4 to 5 with developmental language disorder.
- Trial name
- NCT06275815
- Testing
- Sit Together and Read (STAR), Monetary Reward, Text Encouragement
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Ohio State University
Domestic Violence Against Women, Community-based Prevention
Community Based Intervention to Prevent Domestic Violence Against Women in Ethiopia; a Protocol for Quasi-Experimental Implementation Research
Violence against women is a well understood devastating global pandemic, and human right violation. One in three women experienced intimate partner violence worldwide.
- Conditions
- Domestic Violence Against Women, Community-based Prevention, Interevntion Implementation
- Trial name
- NCT03265626
- Testing
- Intervention 1: Comprehensive preventive intervention, Intervention 2: Awareness creation and community mobilization, available standard care
- Where
- Ethiopia
- Volunteers
- 1,217 people, healthy volunteers welcome
- Sponsor
- Haramaya Unversity
Genetic Predisposition
Initiative for Clinical Long-read Sequencing
The study aims to comprehensively introduce Long-read Genome sequencing (LR-GS) based genetic testing into clinical routine. In order to demonstrate the superiority of untargeted LR-GS over Short-read Genome sequencing (SR-GS) to…
- Trial name
- IonGER (NCT06060184)
- Testing
- Next-Generation Sequencing (NGS)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University Hospital Tuebingen
CBT, LGBTQ
SGM Evidenced-Based Mental Healthcare Implementation
The purpose of the proposed study is to identify effective strategies for implementing lesbian, gay, bisexual, transgender, and queer (LGBTQ)- affirmative Cognitive-Behavioral Therapy (CBT) at LGBTQ community centers across the…
- Trial name
- NCT05890404
- Testing
- LGBTQ-Affirmative CBT Training: Materials Only, LGBTQ-Affirmative CBT Training: Direct Training, LGBTQ-Affirmative CBT Training: Local Supervision
- Where
- United States
- Volunteers
- 1,379 people, healthy volunteers welcome
- Sponsor
- Yale University
Patient Safety, Organizational Change
Generalizing TESTPILOT to New Single Family Room NICUs
Complex service interventions are neither smooth nor easy in any transitioning healthcare facility. Simulations performed in the new environment reinforce patient safety by uncovering safety threats, enabling their correction…
- Trial name
- TESTPILOT (NCT02574104)
- Testing
- Simulate a functional NICU prior to moving patients
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Depression, Anxiety, Suicide
Mental Health in Primary Care
The goal of this study is to evaluate in an effectiveness-implementation type I hybrid trial, an enhanced version of eHealth Familias Unidas for reducing depressive, anxious symptoms and suicide behavior in Hispanic youth.
- Conditions
- Depression, Anxiety, Suicide, Drug Use
- Trial name
- NCT05426057
- Testing
- eHealth Familias Unidas Mental Health
- Where
- 17 sites in United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Miami
PTSD
Implementation of Truma-Focused Cognitive Behavioral Therapy (TF-CBT) in Norway
Trauma-focused cognitive behavioral therapy (TF-CBT) is an evidence-based treatment method for children and adolescents who have been exposed to traumatic experiences and who are experiencing posttraumatic stress symptoms.
- Trial name
- TF-CBT (NCT05248971)
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Volunteers
- 26,500 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Emotion Regulation Abilities, Mental Health
Feasibility and Acceptability of the Asynchronous eParenting CARE Program
This study aims to evaluate the feasibility and acceptability of the eParenting CARE Program, an asynchronous, self-guided emotion-focused parenting intervention for parents of school-aged children (8-13 years).
- Trial name
- NCT07427771
- Testing
- eParenting CARE Program
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
HIV Positive
Implementation and Effectiveness of a Psychosocial Intervention Among Registered People Living With HIV(HIV Patients) at Pakistan Institute of Medical Sciences (PIMS) Islamabad Pakistan.
"Implementation and Effectiveness of a Psychosocial Intervention Among Registered PLHIV at PIMS Islamabad Pakistan." The study aims to evaluate the impact of a structured psychosocial intervention on the mental health and…
- Trial name
- PLHIV (NCT06869330)
- Testing
- psychosocial
- Where
- Pakistan
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Asthma
Rural Asthma Effectiveness Study
The investigators will test if their intervention, Asthma Self-Management for Adolescents (ASMA), an 8-week, high school-based intervention for teenagers, improves asthma in rural high school students with uncontrolled asthma…
- Trial name
- NCT03533764
- Testing
- ASMA
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- Columbia University
Pneumonia
Evaluation of Integrated Community Case Management in Ethiopia
The purpose of this study is to to measure the effect of the HEP+ICCM program relative to routine HEP approach in rural Ethiopia on changes in coverage of case management of common childhood illnesses and severe acute…
- Trial name
- NCT01606267
- Testing
- health systems intervention: HEP+ICCM
- Where
- Ethiopia
- Volunteers
- 607,770 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Tuberculosis Infection, Latent, Tuberculosis Active
SCAF-TB - Saving Children and Their Families From Tuberculosis: Implementation Research to Improve TB Preventive Treatment Initiation and Completion Rates Among Contact Persons in Tajikistan and Tanzania
The SCAF-TB study aims to evaluate how the WHO-endorsed SIILTIBCY skin test can be best implemented to test close contacts for tuberculosis infection (TBI) in Tajikistan and Tanzania, either facility-based or home-based delivered…
- Conditions
- Tuberculosis Infection, Latent, Tuberculosis Active, TPT
- Trial name
- SCAF-TB (NCT07714707)
- Testing
- CY-TB Patch, Audiblehealth DX
- Where
- 2 sites in Tajikistan, Tanzania
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- KNCV Tuberculosis Foundation
Opioid Use Disorder
Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment
The main purpose of this stepped wedge trial will be to test the impact of a bundle of implementation strategies designed to improve ED-outpatient care coordination on long-term buprenorphine retention among adult patients who…
- Trial name
- CONNECT (NCT07024498)
- Testing
- care coordination implementation strategies
- Where
- 4 sites in United States
- Volunteers
- 3,492 people
- Sponsor
- University of California, Davis
Depression, Anxiety
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
The proposed study draws on prior research to evaluate the feasibility, acceptability and explore preliminary effectiveness of Coffee and Family Education and Support, Version (CAFES2) using a pilot randomized type 1 hybrid…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT06261463
- Testing
- CAFES2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Illinois Chicago
Obesity, Childhood
Physical Activity on Prescription for Children With Obesity
Background: physical inactivity is a main cause of childhood obesity. Physical activity on prescription (PAP) is an evidence-based intervention for adults, but has not been evaluated in children with obesity.
- Trial name
- IMPA (NCT04847271)
- Testing
- Physical activity on prescription (PAP)
- Where
- Sweden
- Volunteers
- 42 people
- Sponsor
- Vastra Gotaland Region
Disordered Eating Behaviors
A School-Based Intervention to Prevent Disordered Eating in Middle School Students
This study aimed to develop an educational program for the prevention of disordered eating behaviors among middle school students and to evaluate its effectiveness.
- Trial name
- NCT07885631
- Testing
- School-Based Disordered Eating Prevention Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Substance Use Disorders, Opioid Use Disorder, Severe
EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy
This study is a multi-site, cluster randomized, two group implementation trial comparing a low- versus high-intensity implementation strategy for supporting hospital-based opioid use disorder treatment (HBOT) in community…
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate
- Trial name
- EXHITENTRE (NCT04921787)
- Testing
- Low Intensity, High Intensity
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Gavin Bart