Clinical trials: In-Vitro Fertilization
Infertility
Fresh Vs Frozen Surgical Sperm in IVF
The primary objective of this study is to determine if the use of frozen surgical testicular sperm specimens for ICSI lead to different IVF outcomes when compared with the use of fresh surgical testicular sperm for ICSI.
- Trial name
- NCT03361982
- Testing
- Slow Freezing and Thawing
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
in Vitro Fertilization
ICSI Using Pentoxifylline to Identify Viable Spermatozoa in Absolute Asthenozoospermia Patients
Absolute asthenozoospermia is a rare condition in men with an occurrence frequency of 1/5000 and greatly affects fertility product. Previous studies have shown that the ovum can be fertilized with live but immotile sperm.
- Trial name
- NCT05943353
- Testing
- Pentoxifylline
- Where
- Vietnam
- Volunteers
- 10 people
- Sponsor
- Mỹ Đức Hospital
Polycystic Ovary Syndrome
Metformin Treatment Before in Vitro Fertilization (IVF) in Women With Ultrasound Evidence of Polycystic Ovaries
The aim of study was to investigate whether pre-treatment with metformin before and during IVF increases the live birth rate compared to placebo in women with sonographic evidence of polycystic ovaries (PCO), but without any…
- Trial name
- NCT01046032
- Testing
- Metformin
- Where
- 3 sites in United Kingdom
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Infertility
Implantation and Cytokine Expression
Implantation failure of the embryo might be the result from the environment in the uterus. Proteins (cytokines) are screted by the endometrium which can result in a pro or anti inflammatory environment.
- Trial name
- NCT00264992
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- UMC Utrecht
Polycystic Ovary Syndrome
The Influence Factors of Ovarian Response in PCOS Patients With IVF-ET Treatment
The purpose of this study is to explore the factors which affect ovarian response of PCOS patients with IVF-ET treatment, in order to provide predictive clinical index for the outcome of IVF-ET treatment in PCOS patients.
- Trial name
- NCT02331758
- Testing
- Lifestyle Counseling
- Volunteers
- 1,000 people
- Sponsor
- Peking University Third Hospital
Asthma
Evaluation of the Prevalence of Asthma in a Cohort of Children Born After IVF (Aged 11-15) Compared With a Control Group
Assisted Reproduction Technologies (ART) are increasingly being used worldwide as a result of fertility decline likely caused by changes in both environment and social behaviour.
- Trial name
- EMCeFIV (NCT02636179)
- Testing
- Comparative epidemiological survey
- Where
- France
- Volunteers
- 1,792 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Infertility
Comparison of Two Embryo Transfer Catheters in Patients Undergoing in Vitro Fertilization and Embryo Transfer
In-vitro fertilization (IVF) treatment involves development of multiple follicles following ovarian stimulation, oocyte retrieval and embryo transfer (ET). ET is the final and most crucial step of IVF treatment.
- Trial name
- NCT02024880
- Testing
- Protective catheter group, Conventional catheter group
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The University of Hong Kong
Infertility
A Study Using Micronised Progesterone (Crinone® 8%) in the Luteal Phase Support of Women Undergoing in Vitro Fertilisation (IVF) and Embryo Transfer (ET)
This was an open-label, randomized, comparative, phase III study to evaluate the safety and efficacy of Crinone 8% in comparison with progesterone 60 mg intramuscular (i.m.) administered once a day in luteal phase support in 200…
- Trial name
- NCT01081652
- Testing
- Micronised Progesterone, Progesterone
- Where
- China
- Volunteers
- 238 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility, IVF
Health of IVF Versus IVM Children (FM-BABIES)
The investigators conduct a follow up of our randomized controlled trial (RCT) to investigate the development of children born from In-vitro fertilization (IVF) and In-vitro maturation (IVM), in order to give strong evidence…
- Conditions
- Infertility, IVF, IVM
- Trial name
- FM-BABIES (NCT04296357)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Infertility
Registry Study of Traditional Morphology Grading Combined With Eeva in IVF Treatment
The purpose of this study is to record and evaluate the use of traditional morphology grading combined with Eeva in the treatment of in vitro fertilization.
- Trial name
- MERGE (NCT01816802)
- Testing
- In-vitro fertilization using Eeva
- Where
- 12 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Progyny, Inc.
Infertility
Evaluation of a Mobile Preconception Lifestyle Programme in Couples Undergoing In Vitro Fertilisation
The aim of the PreLiFe RCT is to assess the effects of a new mobile preconception lifestyle programme (PreLiFE-programme) for couples undergoing IVF.
- Trial name
- PreLiFe-RCT (NCT03790449)
- Testing
- PreLiFe-programme, Attention Control Programme
- Where
- 5 sites in Belgium
- Volunteers
- 211 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility
Frozen Embryo Donation Study
The purpose of this study is to improve patient understanding of and interest in donating frozen embryos resulting from in vitro fertilization (IVF) to others undergoing infertility treatment.
- Trial name
- FREDS (NCT01883934)
- Testing
- Enhanced clinic-based support/counseling, Control
- Where
- United States
- Volunteers
- 3,568 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility
Microfluidic Chip Method Versus Density-gradient Centrifugation Method in IVF
Infertile patients attending IVF treatment at the Centre of Assisted Reproduction and Embryology, Queen Mary Hospital and Kwong Wah Hospital will be recruited during ovarian stimulation for IVF.
- Trial name
- NCT06005311
- Testing
- Microfluidic chip, Density-gradient centrifugation
- Where
- China
- Volunteers
- 1,136 people
- Sponsor
- Professor Ernest Hung-Yu Ng
Children Born After Assisted Reproductive Technologies, Health Status
Health Status of Children Born After Assisted Reproductive Technologies
The goal of this observational study is to study the features of psychophysical development and the morbidity patterns of children born after assisted pregnancy, and to identify the connection with the health status of mothers…
- Conditions
- Children Born After Assisted Reproductive Technologies, Health Status, Child Development
- Trial name
- NCT06094998
- Testing
- hemogram examination
- Where
- Kazakhstan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Fertilization in Vitro
Virtual Reality-Supported Hypnofertility
This research was conducted to determine the effect of virtual reality-supported hypnofertility on fertility preparedness, stress and coping with stress in women having in vitro fertilization.
- Trial name
- NCT04755270
- Testing
- VR Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Adiyaman University
IVF, Frozen Embryo Transfer
Lipiodol Prior to FET (LIFE)
Lipiodol® flushing is an effective fertility treatment for women with unexplained infertility. It is speculated that the treatment effect could work through a direct effect of Lipiodol® on the endometrium.
- Conditions
- IVF, Frozen Embryo Transfer, Hysterosalpingography
- Trial name
- LIFE (NCT06563908)
- Testing
- Lipiodol® uterine treatment prior to IVF/ICSI
- Volunteers
- 784 people
- Sponsor
- Mỹ Đức Hospital
Infertility
An Observational Study of Cetrotide® Gonadotropin-releasing Hormone Antagonist (GnRH Antagonist) With GONAL-f® in Assisted Reproductive Technologies (ART)
This is a multicentric, prospective, observational study on the use of Cetrotide to control the endogenous gonadotrophin levels in Gonal-f stimulated ART treatment cycles in the Asia-Pacific region.
- Trial name
- NCT01109654
- Testing
- Cetrorelix acetate and Follitropin alfa
- Where
- Singapore
- Volunteers
- 2,175 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility, in Vitro Fertilization
Ultrasound Guided Embryo Transfer: Abdominal Versus Transvaginal, a RCT
Ultrasound (US) guided embryo transfer (ET) appears to improve pregnancy outcomes in IVF-ET. Most reports are done using a transabdominal (TAS) approach, in contrast to a transvaginal ultrasound (TVS) which does not require a…
- Trial name
- NCT00682071
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Fertilization in Vitro
Designated Drug Use Investigation 1 of Follistim Injection (Study P06130)(COMPLETED)
To evaluate dosage and administration method, efficacy and safety of Puregon and the relationship between background factors of patients and dose and administration method.
- Trial name
- NCT00920361
- Testing
- Follitropin beta
- Volunteers
- 1,664 people
- Sponsor
- Organon and Co