Clinical trials: Incontinence, Urinary
Urinary Incontinence, Stress
Transvaginal Tape (TVT) Secur Versus TVT Randomised Controlled Trial (RCT)
This randomized multi-centre trial will recruit women with stress urinary incontinence who need surgical treatment for their condition.
- Trial name
- NCT00685217
- Testing
- TVT Secur (Gynecare), TVT (Gynecare)
- Where
- 4 sites in Canada
- Volunteers
- 74 people
- Sponsor
- University of Calgary
Primary Nocturnal Enuresis
A Cohort Study on Treating Primary Nocturnal Enuresis by Regulating Central-Peripheral Circadian Rhythm
Primary nocturnal enuresis (PNE), a prevalent pediatric disorder, suffers from therapeutic limitations characterized by low efficacy and high relapse rates.
- Trial name
- NCT07003126
- Testing
- Circadian Rhythm Intervention Combined with Bladder Training, Bladder Training (basic treatment for enuresis)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Children's Medical Center
Primary Monosymptomatic Nocturnal Enuresis
Bedtime Device Restriction and Desmopressin in PMNE.
This randomized controlled trial will evaluate whether restricting bedtime digital-device use improves the response to desmopressin in children with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07776977
- Testing
- Desmopressin, Bedtime digital-device restriction
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Al-Azhar University
Enuresis, Nocturnal
The Behavioral Therapy for Primary Monosymptomatic Nocturnal Enuresis
A prospective randomized clinical study was conducted at Urology departments, faculties of medicine, Fayoum and Cairo Universities.
- Trial name
- NCT07015320
- Testing
- urotherapy, no intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Nocturnal Enuresis, Bedwetting
Transcutaneous Electric Nerve Stimulation (TENS) for the Treatment of Nocturnal Enuresis in Children
Children referred to the pediatric urology clinic for primary nocturnal enuresis will be screened for enrollment. Patients who fail behavioral therapy and who meet inclusion criteria will be offered therapy with a TENS unit.
- Trial name
- NCT02900495
- Testing
- transcutaneous electric nerve stimulation
- Where
- 5 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pelvic Organ Prolapse Vaginal Surgery, Stress Urinary Incontinence in Women
The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.
This study evaluates the efficacy of adding a human amniotic membrane graft to polypropylene mesh surgery for pelvic prolapse and stress urinary incontinence.
- Trial name
- AMPER (NCT07414849)
- Testing
- Sacrospinous Hysteropexy with Mesh, Retropubic Mid-urethral Sling (Bottom-Up), Transobturator Mid-urethral Sling (Out-In)
- Where
- Argentina
- Volunteers
- 330 people
- Sponsor
- Hospital General de Agudos J. M. Penna
Fecal Incontinence, Urinary Incontinence
Safety and Efficacy of Concurrent MACE and Mitrofanoff Procedures
This was a prospective study. The study period was from January 2022 to July 2025. The study included 30 patients suffering from combined fecal and urinary incontinence submitted for concurrent Malone Antigrade continent Enema…
- Trial name
- MitroMACE (NCT07206719)
- Testing
- Malone Antegrade Continent Enema (MACE) and Mitrofanoff procedures
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohammad Daboos
Nocturnal Enuresis in Children
New Treatment for Nocturnal Enuresis in Children
The aim of the study is to evaluate the role of sulbutiamine in treatment of monosymptomatic nocturnal enuresis in children by using it alone or as a combination therapy with tricyclic antidepressants (imipramine+sulbutiamine).
- Trial name
- NCT06497647
- Testing
- Sulbutiamine, Imipramine
- Where
- Egypt
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sohag University
Nocturnal Enuresis, Bedwetting
Optimal Pulse Width Used in Transcutaneous Electrical Nerve Stimulation for Treating Nocturnal Enuresis in Children
Children referred to pediatric urology clinic for primary nocturnal enuresis will be screened for enrollment. Patients who fail will next be offered therapy with a bedwetting alarm device or a TENS unit as an alternative, and…
- Trial name
- NCT06135311
- Testing
- Pulse Width 260us, Pulse Width 50us
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Albany Medical College
Pelvic Organ Prolapse, Urinary Stress Incontinence
Comparison of the Result of TVT Performed at the Time of Prolapse Surgery or 3 Months After
It is unknown whether it is best to do the TVT( procedure for urinary stress incontinence in women) at the time of prolapse surgery or at a later date.
- Trial name
- NCT00308009
- Testing
- Vaginal Repair for prolapse, TVT procedure, TVT and Prolapse surgery
- Volunteers
- 194 people
- Sponsor
- Ullevaal University Hospital
Pain, Incontinence, Urinary
Sumamos Excelencia 2022
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Conditions
- Pain, Incontinence, Urinary, Obesity, Childhood, Breastfeeding
- Trial name
- NCT05466656
- Testing
- Continuous quality improvement cycle model
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Incontinence, Urinary
Whole Body Vibration Training in the Treatment for Children's Incontinence - a Randomized-Controlled Trial
The determined study category is a prospective clinical randomized controlled study to evaluate the effect of WBVT in combination with urophysiotherapy to playfully expand the therapeutic options for children and adolescents with…
- Trial name
- WBVT (NCT04737447)
- Testing
- Whole Body Vibration Training
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Prostate Cancer, Urinary Incontinence
Prospective RCT on Post Prostatectomy Urine Leak
Objectives: Primary: Comparison of proportion of patient achieving continence between the four arms at 6 months. Secondary: Comparison of time to achieve continence between the four arms.
- Trial name
- NCT02367404
- Testing
- Duloxetine, Pelvic Floor Muscle Training
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Institut Mutualiste Montsouris
Sleep Problems, Parasomnias
Sleep in Children Placed in Out-of-home Care
This project aims to contribute to the existing literature on sleep in children placed in out-of-home care by addressing current gaps and integrating the investigation of sleep and associated risk factors, including adverse…
- Conditions
- Sleep Problems, Parasomnias, Enuresis Nocturnal
- Trial name
- NCT07820683
- Testing
- Sleep and Adjustment in Foster care Environments (SAFE) intervention, Sleep Education Support
- Volunteers
- 730 people
- Sponsor
- Vrije Universiteit Brussel
Urinary Incontinence, Stress
Prospective Registry for Patients Undergoing Surgery for Male Stress Urinary Incontinence
This will be a prospective collection of pre-defined parameters on the treatment of male stress urinary incontinence by an artificial urinary sphincter (AUS) and male sling.
- Trial name
- SATURN (NCT02757274)
- Where
- 28 sites in Belgium, Czechia and 7 more
- Volunteers
- 1,054 people
- Sponsor
- European Association of Urology Research Foundation
Overactive Bladder, Parkinson Disease
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease
The impact of urinary symptoms in Parkinson disease (PD) extends beyond worsened well-being. Urinary symptoms common in PD, especially incontinence and nocturia, are major risk factors for falls likely due to the combination of…
- Trial name
- BOSS PD (NCT03149809)
- Testing
- solifenacin, Pelvic floor muscle exercise-based behavioral therapy
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- VA Office of Research and Development
Nocturnal Enuresis
A Double-blind Randomized Clinical Trial on the Efficacy of Magnetic Sacral Roots Stimulation for the Treatment of NE
The purpose of this study is to assess the efficacy of daily sacral root magnetic stimulation for 10 sessions in patients with nocturnal enuresis.Eligible patients were randomized to receive either real or sham repetitive sacral…
- Trial name
- NCT02328092
- Testing
- rSMS in treatment of Nocturnal Enuresis
- Volunteers
- 41 people
- Sponsor
- Assiut University
Urinary Incontinence
Effects of a Multimodal and Multidimensional Intervention on Urinary Incontinence in Young Nulliparous Female Athletes.
A prevalence of urinary incontinence ranging from 5.7% to 80% has been observed in young nulliparous athletes during their activity. The usual recommendations for managing adult women do not seem to be transferable.
- Trial name
- PELVICATHLE (NCT07644273)
- Testing
- Combined pelvic health education and lumbar-pelvic-abdominal stability strengthening programme., Usual activities
- Where
- France
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Overactive Bladder, Incontinence, Daytime Urinary
Botulinum Neurotoxin Type A (BoNT-A) in Paediatric Non-neurogenic Therapy Resistant Overactive Bladder (OAB)
A non-intervention cohort study on the use of Botulinum Neurotoxin Type A (BoNT-A) in Paediatric Non-neurogenic Therapy Resistant Overactive Bladder (OAB). Primary endpoint was the reduction of urinary incontinence.
- Conditions
- Overactive Bladder, Incontinence, Daytime Urinary, Incontinence, Nighttime Urinary
- Trial name
- NCT06569342
- Testing
- Intradetrusor BoNT-A
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- University of Aarhus
Overactive Bladder
Acupuncture Combined With Mirabegron in the Treatment of OAB
Introduction: As conventional treatments for overactive bladder (OAB) have not yet shown satisfactory results, new approaches are needed.
- Trial name
- ACWMITTOOAB (NCT06181019)
- Testing
- 50 mg of mirabegron, acupuncture combined with mirabegron.
- Where
- China
- Volunteers
- 75 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University