Clinical trials: Individual Psychiatric Disorder
Mild Dementia, Moderate Dementia
Touchscreen Technology and Art for People With Dementia in Care Homes
The prevalence of dementia is rapidly growing worldwide, affecting 46.8 million people in 2015. The 2014 Alzheimer's Society report estimated that 311,730 people with dementia were living in care homes in the United Kingdom (UK).
- Trial name
- NCT03773016
- Testing
- Art apps
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Nottingham
Anxiety, Depression
Attention Bias Modification Training for Young People
Attention bias modification training (ABMT) is a computer-based attention training programme designed to modify the way a person's attention is directed to mild threats in the environment.
- Trial name
- NCT02270671
- Testing
- ABMT
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Cognitive Behavioral Group Treatment for Obsessive-compulsive Disorder in Youth
Obsessive-compulsive disorder (OCD) is a debilitating disorder characterized by unwanted intrusive thoughts and disrupting repetitive rituals.
- Conditions
- Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Adolescent
- Trial name
- NCT04891367
- Testing
- Cognitive behavioral therapy
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Aarhus University Hospital
Depression, Depressive Disorder
Mindful Breathing and tDCS for Depression
This study will investigate whether transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) can enhance the therapeutic effect of mindful breathing training (MBT) for adolescent…
- Trial name
- NCT03897699
- Testing
- Transcranial Direct Current Stimulation, Mindful Breathing
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Minnesota
Social Inclusion, Mental Illness
Peer to Community (P2C) Model: A Pilot Randomized Controlled Trial
This study has been designed to conduct a pilot evaluation of a novel model of support aimed at promoting community integration (CI) following homelessness. This model is called the Peer to Community Model (P2C).
- Conditions
- Social Inclusion, Mental Illness, Substance Use Disorders
- Trial name
- NCT05884749
- Testing
- Peer to Community (P2C) Model, Care as Usual (UC)
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Subthreshold Depression, Exercise
The Effect of Exercise on Cognition and Preventing Depression in Young People
It is estimated that approximately 30% of child and adolescents manifest subthreshold depression (including other specified depressive disorder and unspecified depressive disorder), which can further develop into major depression…
- Conditions
- Subthreshold Depression, Exercise, Clinically-well, Cognitive Change
- Trial name
- NCT04816617
- Testing
- Aerobic exercise intervention, Psycho-education
- Where
- China
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Efficacy of PEGASUS
Evaluating PEGASUS - a Group Intervention for Young People With an Autism Spectrum Disorder
When a clinician gives an autism spectrum disorder (ASD) diagnosis they hope this will be helpful to the person receiving it and their family.
- Trial name
- NCT01187940
- Testing
- PEGASUS
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Institute of Child Health
Psychosis, Intellectual Disability
Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant Psychosis
This clinical trial will prove whether a large number of people with intellectual disability and treatment-resistant psychosis could benefit from the use of clozapine.
- Trial name
- CLOZ-AID (NCT04529226)
- Testing
- Clozapine, haloperidol, pimozide, olanzapine, risperidone, amisulpride
- Where
- 20 sites in Spain
- Volunteers
- 75 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Psychosis, Medication Adherence
Piloting MOL Intervention for Neuroleptic Decision Making
The aim of the current study is to pilot a novel intervention to help people explore their decision making around the use of neuroleptic medication.
- Trial name
- NCT03537040
- Testing
- Method of Levels
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester
Adolescent Problem Behavior, Truancy; Unsocialized
Substance Use Interventions for Truant Adolescents
This study evaluates a brief motivation-building intervention for parents and teens to reduce truancy and substance use. It is hypothesized that the motivational intervention will result in better outcomes compared to an…
- Conditions
- Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized
- Trial name
- GOALS (NCT03655574)
- Testing
- Motivational + Family Check-up (MET+FCU), Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brown University
Anxiety Disorders, Panic Disorder
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis
Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake…
- Conditions
- Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02476136
- Testing
- paroxetine, duloxetine, fluoxetine or venlafaxine
- Volunteers
- 8,800 people
- Sponsor
- prof. Peter de Jonge
Opioid-use Disorder, Opioid Dependence
Comparing Two Training Methods for Opioid Wizard
The prevalence of opioid use disorder (OUD) and opioid-related deaths has risen dramatically in recent years. Effective treatments, including medications for opioid use disorder (MOUDs; e.g., buprenorphine-naloxone and methadone)…
- Conditions
- Opioid-use Disorder, Opioid Dependence, Attitude of Health Personnel
- Trial name
- NCT04867382
- Testing
- Online training
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- HealthPartners Institute
Alzheimer Disease
Autologous Human Adipose-Derived Mesenchymal Stem Cells in Alzheimer's Disease
This is a single patient emergency expanded access clinical study to assess the safety of administering autologous AdMSCs to an incurable Alzheimer disease patient.
- Trial name
- NCT04855955
- Testing
- Adipose-Derived Mesenchymal Stem Cells
- Sponsor
- Celltex Therapeutics Corporation
Depression, Anxiety
Generative Artificial Intelligence Intervention and Individual Psychological Counseling on Emotional Distress in Young Adults
This randomized controlled trial aims to evaluate the effectiveness of an AI-based mental health chatbot, Emohaa, in reducing symptoms of depression, anxiety, insomnia, and academic burnout among young adults experiencing…
- Trial name
- NCT06992180
- Testing
- Generative Artificial Intelligence Intervention, Individual Psychological Counseling
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Central University of Finance and Economics, China
Type 1 Diabetes, Eating Disorders
Multi-Site Eating Disorder Prevention Program for Type 1 Diabetes
This study aims to test the effectiveness of an evidence-based eating-disorder prevention program specifically targeted for individuals with Type 1 Diabetes (T1D) compared to an educational control group.
- Trial name
- NCT05399446
- Testing
- Diabetes Body Project, Educational Group
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 280 people
- Sponsor
- Oslo University Hospital
Schizophrenia
A Clinical Study to Evaluate the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia
This is a clinical trial to determine the long-term safety and tolerability of an investigational drug in people with schizophrenia. Participants in the study will receive the drug being studied.
- Trial name
- NCT04109950
- Testing
- SEP-363856
- Where
- 78 sites in United States, Bulgaria and 6 more
- Volunteers
- 463 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Depression in Adolescence, Depressive Disorder
Clinical Effectiveness of TARA Compared to Standard Treatment for Adolescents and Young Adults With Depression
Depressive Disorders constitute an increasing global health concern and available treatments for young people have not been sufficiently effective in haltering this trend.
- Conditions
- Depression in Adolescence, Depressive Disorder, Dysthymia and Chronic Depression
- Trial name
- TARA (NCT04747340)
- Testing
- Training for Awareness Resilience and Action (TARA), Standard treatment
- Where
- 3 sites in Sweden
- Volunteers
- 136 people
- Sponsor
- Umeå University
Post Traumatic Stress Disorder
Online PTSD Treatment for Young People and Carers - Case Series
Post Traumatic Stress Disorder (PTSD) is prevalent and impairing in children and young people. Effective face to face treatments exist, including Cognitive Therapy for PTSD (CT-PTSD), developed by the researchers' group.
- Trial name
- OPTYC (NCT03935035)
- Testing
- internet-delivered Cognitive Therapy for PTSD (iCT)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6 people
- Sponsor
- King's College London
Nursing Home, Dementia
San Rocco Study: Implementation of the Non-pharmacological Therapies for People With Dementia Living in Nursing Home
The goals of this clinical trial are 1) to estimate the number of professional caregivers and the time spent to carry out the non-pharmacological therapies for people with dementia and 2) to evaluate differences between…
- Conditions
- Nursing Home, Dementia, Staff
- Trial name
- NCT05814276
- Testing
- Training on non-pharmacological therapies' methodology
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Associazione Ginco Ticino
Mental Illness, Web
PsYoungSupport - Web-based Support to Young Careers to Persons With Mental Illness
The overall aim with the project PsYoungSupport is to evaluate Internet and communication technology (ICT) health efforts, i.e. information, education and support for young adults (16-25 years) who are first degree relatives or…
- Trial name
- PSYS (NCT02316158)
- Testing
- Web-based support
- Where
- Sweden
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences