Clinical trials: Induction of Anesthesia
Anxiety, Odontophobia
Pain and Placebo Analgesia. Does Extended Information About Dental Procedures Reduce Pain Induced by Dental Treatment?
Information about the effectiveness of treatment has been found to reduce pain, termed placebo analgesia. In this study it will be investigated whether this finding translates to the dental clinic.
- Trial name
- NCT02160028
- Testing
- anesthetics and extended information before dental treatment, anesthetics and standard information before dental treatment
- Where
- Norway
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Elective Urologic Surgeries
Comparison of Peak Airway Pressure and Gastric Insufflation in Manual Ventilation and Pressure-controlled Ventilation With Facemask During Anesthesia Induction in Children
Comparison of peak airway pressure and gastric insufflation in manual ventilation and pressure-controlled ventilation with facemask during anesthesia induction in children.
- Trial name
- NCT02224196
- Testing
- manual ventilation, pressure-controlled ventilation
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Anxiety
Audiovisual Interactive Games to Alleviate Pediatric Perioperative Anxiety
Pediatric anxiety upon induction of anesthesia is widely prevalent and can lead to negative patient psychological impact and hindrance to induction of anesthesia.
- Trial name
- NCT06111742
- Testing
- Bedside Entertainment and Relaxation Theater (BERT)
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Yale University
Gastric Insufflation
Efficacy of Mechanical Ventilation With Facial Mask to Reduce Gastric Insufflation
The purpose of this study is to determine whether mechanical ventilation with facial mask during induction anesthesia in the population of 1month to 14years is associated with less risk of gastric insufflations as compared with…
- Trial name
- NCT01652924
- Testing
- Mechanical ventilation with facial mask, Manual ventilation with facial mask
- Where
- Colombia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary)
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy.
- Conditions
- Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
- Trial name
- NCT07573150
- Testing
- Infrared Pupillometry
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NeurOptics Inc
Transversus Abdominis Plane (TAP) Block, Wound Infiltration
Ultrasound-guided Transversus Abdominis Plane Block Versus Local Wound Infiltration (TAP_WI)
The goal of this clinical trial is to learn if transversus abdominis plane (TAP) block will reduce the cumulative opioid consumption compared to local wound infiltration (WI).
- Conditions
- Transversus Abdominis Plane (TAP) Block, Wound Infiltration, Pain Score (VAS), Opioid Analgesia
- Trial name
- TAP (NCT06627946)
- Testing
- TAP group
- Where
- Bhutan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
General Anesthesia-Induced Altered Consciousness
Brain Activity and Changes in Consciousness During General Anesthesia
This study aims to investigate how general anesthetics alter brain activity and consciousness across different age groups. The study will evaluate four anesthetic agents with different mechanisms of action: propofol, remimazolam…
- Trial name
- NCT07836205
- Testing
- Propofol (Group P), Remimazolam group, Esketamine group
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Electroencephalography, Anesthesia
Predictive Model in EEG for Induction and Emergence in Pediatric With Propofol
Anesthesia is essential to control pain and produce unconsciousness during surgery and other procedures during childhood. The anesthetic deepness is measured indirectly through changes in blood pressure and heart rate or can be…
- Conditions
- Electroencephalography, Anesthesia, Children, Only
- Trial name
- EEGPED (NCT03705338)
- Testing
- Electroencephalography, Propofol
- Where
- Chile
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Victor Contreras, MSN
Anxiety State, Child Behavior
The Effect of Child Choice With Accompanying Parent on Postoperative Delirium During Induction of Anesthesia
Induction of anesthesia can be distressing both for children and their parents. Nonpharmacological behavioral interventions can reduce the anxiety of children without significant adverse effects as seen with sedative drugs.
- Conditions
- Anxiety State, Child Behavior, Postoperative Delirium
- Trial name
- NCT05931770
- Testing
- Selection of parent(mother or father) according to children preference, Parent (mother or father) selection according to parents' preference
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Obstructive Sleep Apnea
Mask Study: One-handed vs. Two Handed Technique in Children
During induction of anesthesia in children, the investigators have observed significant variability in mask holding technique at our institution among different anesthesia practitioners.
- Trial name
- NCT03215121
- Testing
- One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Anesthesia Induced Atelectasis
Evaluation of the Effect of Lung Recruitment and Positive End- Expiratory Pressure (PEEP) on Anesthesia Induced Atelectasis Using Lung Ultrasound
Atelectasis is a side effect of general anesthesia which can be found in all types of interventions and patients of all ages.1-3 The reported incidence of anesthesia- induced atelectasis in children varies, ranging from 12 to 42%…
- Trial name
- NCT03069157
- Testing
- lung recruitment maneuver
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Burst Suppression, General Anesthesia
Interrater Variability for the Identification of Anesthetic-induced Burst Suppression EEG
Burst suppression describes a specific EEG pattern that can generally indicate a too deep general anesthesia. The pathophysiology of anesthetic-induced Burst Suppression may be distinctly different from the pathophysiology of…
- Conditions
- Burst Suppression, General Anesthesia, Electroencephalogram
- Trial name
- NCT05508386
- Testing
- MATLAB-based interface, showing 50 EEG traces, classification of the EEG-pattern as Burst Suppression possible, yes, no.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Tonsillectomy
Effects of Virtual Reality on Pre-Operative Anxiety and Induction of Anesthesia in Children and Adolescents
Pain and anxiety have a direct correlation. Patients who experience anxiety are more susceptible to feeling pain, and patients who experience pain are more likely to have a component of anxiety associated with their pain.
- Trial name
- NCT03239743
- Testing
- Virtual Reality, Midazolam
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Valley Anesthesiology Consultants
Children Under General Anesthesia
Study on Changes of Pulse Oximeter Plethysmographic Amplitude Induced by Respiration in Pediatric Patients
The purpose of this study is to evaluate the variations of respiratory changes in pulse oximeter plethysmographic amplitude (delta POP) according to different contact forces between finger and sensor of pulse oximeter.
- Trial name
- NCT02940938
- Testing
- Applying pulse oximeter sensor
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Dental Caries in Children, Dental Diseases
Gurney Journey: Virtual Reality Distraction
The aim of this study is to determine whether a software virtual reality (VR) program provided during transportation to anesthesia induction reduces anxiety before the procedure, and compliance in pediatric patients.
- Conditions
- Dental Caries in Children, Dental Diseases, Gastrointestinal Surgery, Procedures Requiring Anesthesia
- Trial name
- NCT06283108
- Testing
- Standard Child Life Preparation and Support + Meta Quest 2 VR headset with Gurney Journey (a mixed reality experience), Standard Child Life Preparation and Support
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Colorado
Ventilation
Manual Ventilation Versus Pressure Controlled Mechanical Ventilation in Children
The investigator will compare the feasibility of manual ventilation and pressure-controlled mechanical ventilation during facemask ventilation in children.
- Trial name
- NCT02751047
- Testing
- manual ventilation, Pressure controlled mechanical ventilation
- Where
- South Korea
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postoperative Recovery
Ketamin Plus Propofol for Anesthesia Induction
ASA I-II 112 pediatric patients will recruit who underwent adenoidectomy-tonsillectomy surgery. Propofol 1 mg/kg + ketamin1 mg/kg (1/1 ratio) for group I; propofol 1,5 mg/kg + ketamin 0,75 mg/kg (2/1 ratio) for group II; propofol…
- Trial name
- NCT04761159
- Testing
- Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Movement After Intravenous Cannulation
Optimum Time for Intravenous Cannulation After Induction With Sevoflurane in Pediatric Patient
This study aimed to determinate effective dose 95 (ED95) intravenous cannulation in pediatric patient after induction of sevoflurane 8 vol%
- Trial name
- NCT04284579
- Testing
- IV cannula
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia