Clinical trials: Induction of General Anesthesia
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Hypotension on Induction
Hypotension in Children With Down Syndrome With Anesthesia Induction
Children generally undergo induction of anesthesia by inhalation of sevoflurane. Children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane.
- Trial name
- NCT04603469
- Testing
- Non invasive blood pressure
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Baylor College of Medicine
Anxiety at Induction of Pediatric Anesthesia
Improving the Quality of Anesthesia Induction by Reducing Preoperative Anxiety in the Operating Room
Preoperative anxiety refers to a range of physical and/or psychological manifestations, which can have a significant impact on medical outcomes and the experience of the child and their parents.
- Trial name
- QUALIN (NCT06972420)
- Testing
- Hypnosis session
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Negative Behaviour Change
Pilot Study: Intraoperative Clonidine and Postoperative Behaviour
Children who are upset during induction of general anaesthesia are frequently distressed postoperatively and are more likely to demonstrate negative behaviour changes.
- Trial name
- NCT02324413
- Testing
- Clonidine
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Richard Beringer
Intravenous Access, Pediatric Patient
Intravenous Access Time in Pediatric Patients
In pediatric patients with no vascular access, anesthesia induction is usually achieved with sevoflurane. The aim of investigators to evaluate the optimum intravenous access time and the corresponding bispectral index (BIS) value…
- Trial name
- NCT04190407
- Testing
- Intravenous access
- Volunteers
- 84 people
- Sponsor
- Istanbul Medeniyet University
Fasting Period, Intravascular Volume
The Impact of Preoperative Fasting Period on Cardiac Index Variability After Anesthesia Induction in Pediatric Patients
The minimum period of fasting recommended by the 'American Society of Anesthesiologists' for the preoperative period is 6 hours for solid foods and 2 hours for clear liquids.
- Trial name
- NCT03406481
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Marmara University
Bidirectional Endoscopy
ED90 of Remimazolam Anesthesia Induction in Painless Bidirectional Endoscopy in Children
Exploring the ED90 of remimazolam in pediatric bidirectional endoscopy at different age groups.
- Trial name
- ED90 (NCT06121609)
- Testing
- Remimazolam
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Tongji Hospital
Anesthesia, General, Neuromuscular Blockade
Pharmacokinetic-pharmacodynamic Analysis of Sugammadex for Conventional Reversal in Children
This study administers sugammadex sodium to pediatric patients under general anesthesia with rocuronium. Pharmacokinetic and pharmacodynamic analysis are performed based on plasma concentration of sugammadex sodium and monitoring…
- Trial name
- NCT04347486
- Testing
- Sugammadex Injection 2mg/kg, Sugammadex Injection 4mg/kg, Sugammadex Injection 8mg/kg
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Seoul National University Hospital
Cannulation, Sevoflurane Induction
Determination of Optimum Time for Intravenous Cannulation in Children With Dexmedetomidine Premedication
Inhalational induction with sevoflurane, nitrous oxide, and oxygen is accepted as a safe technique to avoid any movement during intravenous cannulation in children.
- Conditions
- Cannulation, Sevoflurane Induction, Dexmedetomidine
- Trial name
- NCT05139212
- Testing
- Optimum time for intravenous cannulation in children premedicated with dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
General Anesthesia
Gastric Ultrasound in Paediatric Anaesthesia
Anesthesia for emergency surgery is a situation at risk of pulmonary aspiration of gastric contents. It has been previously reported that bedside two-dimensional ultrasonography can be a useful tool for anesthesiologists to…
- Trial name
- ECHOGASTRO (NCT02584348)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Atelectasis
Continuous Positive Airway Pressure Decreased Lung Collapse During General Anesthesia Induction in Pediatric Patients
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT03461770
- Testing
- CPAP
- Where
- Argentina
- Volunteers
- 42 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Bronchospasm
Bronchospasm During Anesthetic Induction: Study of Clinical Characteristics and Treatments Administered According to Etiology
Bronchospasm during anaesthesia is a rare but potentially life-threatening event. They are classically part of IgE-dependent anaphylaxis but can also occur as an independent clinical entity, triggered by inflammatory factors such…
- Trial name
- NCT05025709
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Central Hospital, Nancy, France
Emergence Agitation
Sevoflurane Induced Emergence Agitation
Investigators evaluated the effect of intranasal ketamine or alfentanil addition to oral midazolam for prevention of emergence agitation.Seventy-eight, 1-8 year-old children, undergoing urological surgery with sevoflurane…
- Trial name
- NCT02022488
- Testing
- midazolam, alfentanil, ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Yeditepe University Hospital
Apnea
Fraction of Oxygen on Induction of Anesthesia in Infants
Invesetigators evaluated the effect of positive end-expiratory pressure during anaesthesia induction on nonhypoxic apnoea time in infants.
- Trial name
- PEEP (NCT04722276)
- Testing
- positive end expiratory pressure, fraction of inspired oxygen 80%
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Anesthesia Complication, Hypotension on Induction
Ultrasound Assessment of the Subclavian Vein for Predicting Hypotension in Children After Anaesthesia Induction
Intra operative hypotension is a risk factor in pediatric anesthesia (McCann ME et al.Pediatr Anesth 2014; 24: 68-73). In summary, the study aims at examine if ultrasound assessment of the diameter and collapsibility index of the…
- Conditions
- Anesthesia Complication, Hypotension on Induction, Hypovolemia
- Trial name
- NCT04573842
- Testing
- Ultrasound assessment of SCV
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Induction of General Anesthesia
Effect of High-flow Nasal Oxygenation on Gastric Insufflation in Children
This is a randomized controlled study to compare the incidence of gastric insufflation when using high-flow nasal oxygenation and facemask ventilation in pediatric patients.
- Trial name
- NCT06204653
- Testing
- HFNO group, MV group
- Volunteers
- 70 people
- Sponsor
- Ajou University School of Medicine
Anaesthesia Induction
Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial
Intravenous anaesthesia induction is nowadays considered as gold standard, mainly because of the possibility of the rapid therapeutic intervention while having secured i.v. line.
- Trial name
- Induration (NCT04527757)
- Testing
- Inhalation induction, Intravenous induction
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Brno University Hospital
Neuromuscular Blockade
Comparing Reversal With Neostigmine and Sugammadex in Paediatric
A reversal agent is commonly given to improve neuromuscular function after intra-operative administration of non-depolarizing neuromuscular blocking agents.
- Trial name
- JS (NCT03137290)
- Testing
- Neostigmine, Sugammadex Sodium
- Where
- Malaysia
- Volunteers
- 80 people
- Sponsor
- Universiti Sains Malaysia
Chalazion
Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery
This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery.
- Trial name
- SEVO-PED (NCT07450495)
- Testing
- Sevoflurane
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Hypothermia
Temperature Changes During Induction of General Anesthesia in Pediatric Patients
We aim that uncovering patients during induction of general anesthesia does not decrease core body temperature in pediatric patients.
- Trial name
- NCT00710320
- Testing
- Covered and uncovered anesthesia induction
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma