Clinical trials: Induction of General Anesthesia
Anaesthesia Induction
Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial
Intravenous anaesthesia induction is nowadays considered as gold standard, mainly because of the possibility of the rapid therapeutic intervention while having secured i.v. line.
- Trial name
- Induration (NCT04527757)
- Testing
- Inhalation induction, Intravenous induction
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Brno University Hospital
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Anesthesia, Parent-Child Relations
Parental Presence at Anesthesia Induction
Parental presence during induction for young infants is still debated. There is a paucity of information on the real-world interaction between parents, infant and the anesthesia team.
- Trial name
- PPAI (NCT05787717)
- Testing
- Parental presence
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University Hospital
Respiratory Tract Infection
This Study Evaluated the Safety of Awake Extubation in Children at Risk for Respiratory Events Undergoing General Anesthesia.
The primary aim of this study was to evaluate the safety of awake extubation in children at risk for PRAEs undergoing general anesthesia.
- Trial name
- NCT06936761
- Testing
- Propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 425 people
- Sponsor
- Selcuk University
Pediatric, ED95
The ED95 of Single Intravenous Bolus Remimazolam Besylate in Pediatric Patients During General Anesthesia Induction
Due to the incomplete development of systems and low pain thresholds in the pediatric population, good general anesthesia is required during the perioperative period to ensure the smooth progress of the surgery.Propofol is often…
- Conditions
- Pediatric, ED95, Sedation, General Anesthesia
- Trial name
- NCT06061159
- Testing
- Remimazolam besylate
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Noise Exposure
The Effect of a Reduced Noise Environment on the Response Time of the Anesthesia Provider
This project will investigate whether reduction in ambient light and elimination of noise during induction and emergence from anesthesia influences the response time of the anesthesia provider to auditory and visual alarms when…
- Trial name
- NCT03507855
- Testing
- Reduced noise, Normal
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Joshua Uffman
Apnea
Fraction of Oxygen on Induction of Anesthesia in Infants
Invesetigators evaluated the effect of positive end-expiratory pressure during anaesthesia induction on nonhypoxic apnoea time in infants.
- Trial name
- PEEP (NCT04722276)
- Testing
- positive end expiratory pressure, fraction of inspired oxygen 80%
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Anxiety, Separation, Psychomotor Agitation
Cartoon Distraction and Parental Presence on Anxiety in Pediatric Anesthesia
Nearly 50% of young children undergoing surgery exhibit high level of anxiety during induction of anesthesia because of exposure to unfamiliar environment and people and separation from parents.
- Trial name
- NCT02027844
- Testing
- Cartoon, parental presence
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Yeungnam University College of Medicine
Dental Caries in Children, Dental Diseases
Gurney Journey: Virtual Reality Distraction
The aim of this study is to determine whether a software virtual reality (VR) program provided during transportation to anesthesia induction reduces anxiety before the procedure, and compliance in pediatric patients.
- Conditions
- Dental Caries in Children, Dental Diseases, Gastrointestinal Surgery, Procedures Requiring Anesthesia
- Trial name
- NCT06283108
- Testing
- Standard Child Life Preparation and Support + Meta Quest 2 VR headset with Gurney Journey (a mixed reality experience), Standard Child Life Preparation and Support
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Colorado
Anesthesia
Dose of Remi in Children
Remimazolam has demonstrated the potential as a valuable medication for procedural sedation and general anesthesia. However, the effective dosage of remimazolam in pediatric patients is still unknown.
- Trial name
- DRINK (NCT05990673)
- Testing
- Remimazolam
- Volunteers
- 25 people
- Sponsor
- Zhihong LU
Anesthesia Complication, Hypotension on Induction
Ultrasound Assessment of the Subclavian Vein for Predicting Hypotension in Children After Anaesthesia Induction
Intra operative hypotension is a risk factor in pediatric anesthesia (McCann ME et al.Pediatr Anesth 2014; 24: 68-73). In summary, the study aims at examine if ultrasound assessment of the diameter and collapsibility index of the…
- Conditions
- Anesthesia Complication, Hypotension on Induction, Hypovolemia
- Trial name
- NCT04573842
- Testing
- Ultrasound assessment of SCV
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anesthetic, Sevoflurane
Sevoflurane Concentrations in Children
The sevoflurane concentrations (as well as vital signs, child's date of birth, type of surgery) will be recorded during the first 10 minutes of anesthesia.
- Conditions
- Anesthetic, Sevoflurane, Age
- Trial name
- NCT06510803
- Testing
- The washin of sevoflurane in the GE Ohmeda workstation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- State University of New York at Buffalo
Pain on Propofol IV Injection
In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?
The purpose of this study is to evaluate if the Synera Patch (lidocaine/tetracaine patch), used to numb the skin before IV placement, is effective in reducing pain associated with propofol IV administration when inducing general…
- Trial name
- Synera patch (NCT01576770)
- Testing
- lidocaine/tetracaine transdermal patch (NDC 43469-864-01), Gebauer's Ethyl Chloride
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Children Under General Anesthesia
Study on Changes of Pulse Oximeter Plethysmographic Amplitude Induced by Respiration in Pediatric Patients
The purpose of this study is to evaluate the variations of respiratory changes in pulse oximeter plethysmographic amplitude (delta POP) according to different contact forces between finger and sensor of pulse oximeter.
- Trial name
- NCT02940938
- Testing
- Applying pulse oximeter sensor
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Anesthesia Complication
Effect of Midazolam Premedication on Mask Ventilation Difficulty
Mask ventilation has great importance during anesthesia induction because it is the only way to oxygenate patients who have lost consciousness and spontaneous breathing.
- Trial name
- NCT05368441
- Testing
- Midazolam, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karaman Training and Research Hospital
Intravenous Access, Pediatric Patient
Intravenous Access Time in Pediatric Patients
In pediatric patients with no vascular access, anesthesia induction is usually achieved with sevoflurane. The aim of investigators to evaluate the optimum intravenous access time and the corresponding bispectral index (BIS) value…
- Trial name
- NCT04190407
- Testing
- Intravenous access
- Volunteers
- 84 people
- Sponsor
- Istanbul Medeniyet University
Negative Behaviour Change
Pilot Study: Intraoperative Clonidine and Postoperative Behaviour
Children who are upset during induction of general anaesthesia are frequently distressed postoperatively and are more likely to demonstrate negative behaviour changes.
- Trial name
- NCT02324413
- Testing
- Clonidine
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Richard Beringer
Airway Obstruction
Effectiveness Of Apneic Oxygenation During Induction Of General Anesthesia In Children
During general anesthesia, the administration of anesthetics and muscle relaxants induces apnea, wherein spontaneous breathing ceases .
- Trial name
- NCT06742476
- Testing
- nasal cannula
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Fayoum University Hospital
Neuromuscular Blockade
Comparing Reversal With Neostigmine and Sugammadex in Paediatric
A reversal agent is commonly given to improve neuromuscular function after intra-operative administration of non-depolarizing neuromuscular blocking agents.
- Trial name
- JS (NCT03137290)
- Testing
- Neostigmine, Sugammadex Sodium
- Where
- Malaysia
- Volunteers
- 80 people
- Sponsor
- Universiti Sains Malaysia
Anesthesia; Reaction, Children, Only
Effect of Anesthesia Induction on Cerebral Hemodynamic in Children
General anesthesia induces hemodynamic changes, notably a reduction of arterial blood pressure going up to 30%, that may impact cerebral perfusion and oxygenation.The purpose of this study is to assess the impact of anesthesia on…
- Trial name
- PEDICACHE (NCT04581213)
- Testing
- General anesthesia
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Justine's Hospital