Clinical trials: Infant, Late
Lung Diseases, Bronchopulmonary Dysplasia
Late Sequelae of Bronchopulmonary Dysplasia
To measure the cardiopulmonary function in individuals who developed bronchopulmonary dysplasia (BPD) at Stanford University Medical Center from 1964-1973 and to determine the factors associated with the presence of…
- Trial name
- NCT00005287
- Sponsor
- Stanford University
Late Premature Infants, Systemic Nutritional Management
Research of Systemic Management for Late Preterm Infants Nutrition in China
The purpose of the project is to investigate the status of nutrition management of late preterm infants in the member hospitals in the Beijing association of preterm infants, and set up the systemic nutritional management of late…
- Trial name
- NLP (NCT02605577)
- Testing
- new systemic nutrition management protocol
- Volunteers
- 2,000 people
- Sponsor
- Peking Union Medical College Hospital
Asphyxia
Resuscitation of Late-preterm Infants by Using Room Air or 100% Oxygen
In this randomized control trial, the investigators hypothesize that late-preterm infants resuscitated with a "low oxygen delivery" strategy (initiation of resuscitation with room air) will result in a significant reduction in…
- Trial name
- NCT01305031
- Testing
- Resuscitation, 100% oxygen
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Nanjing Medical University
Breastfeeding
Cup Versus Bottle Feeding for Late Preterm Infants
The purpose of the current study is to investigate the effect of using cup feeding for preterm infants during NICU stay on breastfeeding outcomes after discharge. The following hypotheses are being tested: 1.
- Trial name
- NCT00756587
- Testing
- Cup Feeding, Bottle Feeding
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
VLBW - Very Low Birth Weight Infant
Peripherel Perfusion Index to Predict Sepsis in Very Low Birth Weight Infants
To explore the predictive value of peripheral perfusion index in late onset sepsis of very low birth weight infants , obtain the threshold by observing the perfusion index of very low birth-weight infants within one month after…
- Trial name
- NCT05224921
- Testing
- Not applicable (cohort study)
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Children's Hospital of Fudan University
Hematocrit Anemia, Acidosis
Placental Transfusion in the 'Natural' Delivery: Effect of Early and Late Umbilical Cord Clamping
The investigators conducted a randomized controlled trial (parallel group study with 1:1 randomisation) comparing early cord clamping (ECC, at 60 seconds) and delayed cord clamping (DCC, at 180 seconds) in 90 cases of 'normal'…
- Trial name
- NCT04459442
- Testing
- Umbilical cord clamping at birth.
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Policlinico Abano Terme
Persistent Pulmonary Hypertension of the Newborn, Hypoxemic Respiratory Failure
Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension
The purpose of this research is to evaluate two oxygen saturation goals for newborns with pulmonary hypertension. Participation in this research will involve random assignment to one of two oxygen saturation goals, review of the…
- Trial name
- POST-IT (NCT04938167)
- Testing
- 95% - 99% SpO2 target
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of California, Davis
Prematurity
Oral Care With Colostrum for Preventing Late-onset Sepsis in Preterm Infants
This clinical trial aimed to evaluate the efficacy of the oral mother's colostrum administration for preventing late-onset sepsis in premature neonates during their stay in the neonatal intensive care unit.
- Trial name
- NCT06534632
- Testing
- Mother's colostrum
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- General Organization for Teaching Hospitals and Institutes
Lysosomal Acid Lipase Deficiency
Acid Lipase Replacement Investigating Safety and Efficacy (ARISE) in Participants With Lysosomal Acid Lipase Deficiency
This Phase 3 study evaluated the efficacy and safety of 1 milligram/kilogram (mg/kg) intravenous (IV) infusions of SBC-102 (sebelipase alfa) administered every other week (qow) in participants with late onset lysosomal acid…
- Trial name
- ARISE (NCT01757184)
- Testing
- Sebelipase Alfa
- Where
- 40 sites in United States, Argentina and 13 more
- Volunteers
- 66 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Late-Onset Neonatal Sepsis
Clinical Impact of Donor Milk Pasteurized by HTST Treatment in Preterm Infants
Randomized double-blind clinical trial to compare the incidence of microbiological proven late onset sepsis in extremely preterm infants (<1000 grams) that are supplemented with donor milk pasteurized by High Temperature Short…
- Trial name
- NCT04424667
- Testing
- donor milk
- Where
- 2 sites in Spain
- Volunteers
- 211 people
- Sponsor
- Carmen Rosa Pallas
Latent Iron Deficiency at Birth
Latent Iron Deficiency at Birth Influences Auditory Neural Maturation in Late Preterm and Term Infants
This study evaluates auditory neural maturation by auditory brainstem evoked response in late preterm and term infants with in utero iron deficiency compared with neonates with normal in utero iron status.
- Trial name
- NCT02503397
- Testing
- Auditory brainstem evoked response (ABR)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sir Ganga Ram Hospital
Neonatal Late Onset Sepsis
Pentoxifylline Dose Optimization in Neonatal Sepsis
Sepsis is a very important cause of death and morbidity in preterm infants. There are strong indications that preterm neonates with sepsis could benefit, next to antibiotics, from treatment with pentoxifylline (PTX).
- Trial name
- NCT04152980
- Testing
- Pentoxifylline
- Where
- 2 sites in Netherlands, Poland
- Volunteers
- 30 people
- Sponsor
- Erasmus Medical Center
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis
Effects of Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study was to see if a brief delay in cord clamping for 30 to 45 seconds would result in higher hematocrit levels, fewer transfusions, healthier lungs, and better motor function at 40 wks and 7 months of age.
- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis
- Trial name
- NCT00840983
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Rhode Island
Time for Achievement of Full Feeds
Early Versus Late Initiation of Feeding in Preterm Newborns With Prenatal AREDF in Umbilical Artery
This research is being conducted in preterm newborns with 'in utero' growth restriction due to inadequate blood flow from the mother to the baby.
- Trial name
- AREDF (NCT01759615)
- Testing
- Early Enteral feeding, Late enteral feeding
- Volunteers
- 60 people
- Sponsor
- Lady Hardinge Medical College
Intraventricular Hemorrhage, Hydrocephalus
Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants
Intraventricular hemorrhage remains the most frequent, severe neurological complication of prematurity, occurring in 25-30% of preterm infants.
- Trial name
- LETAP (NCT00875758)
- Testing
- Removal of CSF through ventricular access device, Removal of CSF through a ventricular access device
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Washington University School of Medicine
Infant, Newborn, Hypotension
Hypotension in Neonates
This observational study collects information on the current incidence and management of hypotension in babies born at term or late preterm that are admitted to Neonatal Intensive Care Units (NICUs) within the Neonatal Research…
- Conditions
- Infant, Newborn, Hypotension, Blood Pressure
- Trial name
- NCT00882284
- Where
- 17 sites in United States
- Volunteers
- 820 people
- Sponsor
- NICHD Neonatal Research Network
Gastroesophageal Reflux, Bronchopulmonary Dysplasia
GER Poses a Potential Risk for Late Complications of BPD
Bronchopulmonary dysplasia (BPD) is a common condition in the low birth weight infants. Although most of the BPD symptoms improved after a regular treatment in infancy, there are still a few late complications left such as the…
- Trial name
- NCT03014453
- Where
- China
- Volunteers
- 187 people
- Sponsor
- Shengjing Hospital
Neonatal Sepsis
Study of the Breast Milk Microbiota and Its Influence on the Development of Early and Late Neonatal Bacterial Sepsis Under Three Months of Age.
Breast milk contains many microorganisms including bacteria that are beneficial to health (probiotics), but also bacteria that are generally considered pathogenic.
- Trial name
- MINEOS (NCT05490498)
- Testing
- Collection of breast milk
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Swallow, Preterm Infant
Effect of Kinesio-taping Technique on Oral Feeding in Late Preterm Infants
Difficulty in feeding among late preterm infants is one of the most significant factors contributing to prolonged hospitalization and re-admissions.
- Conditions
- Swallow, Preterm Infant, Newborn, Kinesiotaping
- Trial name
- NCT06208228
- Testing
- Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ondokuz Mayıs University
CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection
Neonatal Catheter Lock for Infection Prevention
For newborns admitted to Neonatal Intensive Care Units (NICUs), one of the main risk factors for late-onset sepsis is the presence of a central venous catheter (CVC), which is often essential for the administration of medications…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection, Neonatal Sepsis, Late-Onset
- Trial name
- Neo-CLIP (NCT07585188)
- Testing
- Taurolidine 2% lock, Normal saline lock
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- University of Turin, Italy