Clinical trials: Infant Development
Preterm Infant Development, COVID - 19
Development of Preterm Infants Born During the COVID-19 Pandemic
This study aims to evaluate differences in cognitive and psychomotor development among preterm infants (born before 34 weeks of gestation) delivered during the COVID-19 pandemic at Hospital de la Santa Creu i Sant Pau, compared…
- Trial name
- NCT07569523
- Testing
- Evaluation of cognitive and psychomotor development through the Bayley Scales Of Infant and Toddler Development and Wechsler Preschool and Primary Scale of Intelligence
- Volunteers
- 120 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Bronchopulmonary Dysplasia
MRI in BPD Subjects
The investigators are wanting to learn more about early development of the lungs and to help them better understand prematurity and the development of a breathing disorder call BPD (Bronchopulmonary Dysplasia)
- Trial name
- NCT03657693
- Testing
- NICU MRI, Polysomnography
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Klinefelter Syndrome
TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY
This research study in infant males with Klinefelter syndrome (47,XXY) will learn more about the effect of testosterone on early health and development.
- Trial name
- TESTO (NCT03325647)
- Testing
- Testosterone Cypionate 200 Milligram/Milliliter Injectable Solution
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Colorado, Denver
Hypoxic-Ischemic Encephalopathy, Birth Asphyxia
Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)
An extension of the MIDAB trial, the MIDAB-Follow-up trial will evaluate the neurodevelopmental outcomes at 22-26 months age of term/late preterm infants who were depressed at birth and received umbilical cord milking (UCM) or…
- Trial name
- MIDAB-FU (NCT03681314)
- Testing
- Umbilical Cord Milking
- Where
- 3 sites in India
- Sponsor
- Nemours Children's Clinic
Dermatitis, Atopic, Eczema, Infantile
Goat Infant Formula Feeding and Eczema (the GIraFFE Study)
To determine the relative risk of developing atopic dermatitis in infants fed a study formula based on whole goat milk compared to infants a study formula based on cow milk protein.
- Conditions
- Dermatitis, Atopic, Eczema, Infantile, Infant Development, Child Development
- Trial name
- GIraFFE (NCT04599946)
- Testing
- Infant formula and follow-on formula made from whole goat milk, Infant formula and follow-on formula made from cow's milk ingredients
- Where
- 12 sites in Germany, Poland and 1 more
- Volunteers
- 2,132 people, healthy volunteers welcome
- Sponsor
- Dairy Goat Co-operative (N.Z.) Limited
Infant Development, Glucose, High Blood
Effect of Nutritional Intervention on Metabolic Response in Infants
The purpose of this study is to determine the glucose response of complementary feeding regimens consisting of two different follow-up formulas (FUFs) and infant cereals (ICs).
- Trial name
- NCT04483453
- Testing
- EXPL feeding regimen, CTRL feeding regimen
- Where
- Philippines
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Congenital Hip Dysplasia
Early Abduction Splintage on Stable Hips in Infants With Developmental Dysplasia of the Hip
The aim of this study is to prove the improvement of pubo-femoral distance by early abduction splintage in one-month-old infants with developmental dysplasia of the hip (with a clinical stable hip but an abnormal hip…
- Trial name
- BBH (NCT02885831)
- Testing
- Abduction splintage
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Brest
Development, Infant, Respiratory Distress Syndrome in Premature Infant
Effect of Chest Physiotherapy on the Development of Preterm Infants.
The aim of this study is to investigate the effect of the stimulation of "reflex rolling" from the Vojta method and the effect of the expiratory flow increase technique on the development of the preterm infants.
- Trial name
- NCT04689386
- Testing
- Group I (GE-I) - Stimulation of "reflex rolling" from the Vojta method, Group II (GE-II) - expiratory flow increase technique
- Where
- 3 sites in Spain
- Volunteers
- 51 people
- Sponsor
- Universidad de Murcia
Obesity, Weight Gain
Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development
NCDs are observed mostly in adults, however there is strong evidence that suggests NCDs origin early in life, thus the first 1000 days of life (conception to age 2yrs).
- Conditions
- Obesity, Weight Gain, Metabolic Diseases, Birth Weight
- Trial name
- NCT01916603
- Testing
- Normative Intervention
- Where
- Chile
- Volunteers
- 2,400 people
- Sponsor
- University of Chile
Autism Spectrum Disorder, Sleep Disorder
Effect of Snoezelen-Based Occupational Therapy Intervention on Sleep and Behavior Problems in Infant at Risk of Autism
Objective: Sleep and behavioral problems are common in infants at risk of autism. This study aims to examine the effect of Snoezelen-Based Occupational Therapy intervention on sleep and behavioral problems in infants at risk of…
- Conditions
- Autism Spectrum Disorder, Sleep Disorder, Behavior Problem
- Trial name
- NCT06164210
- Testing
- Snoezelen-Based Occupational Therapy Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ankara University
Allergy
The Prolonged Effect of Consumption of a Partially Hydrolyzed Infant Formula During the First 6 Months of Life on the Development of Allergic Manifestations At 5 Years of Age
The present study is a 5-year follow-up of the Allergy Reduction Trial (A.R.T.) birth cohort study of 551 infants at high-risk for allergy. The A.R.T.
- Trial name
- NCT05418491
- Testing
- No intervention is used in the current study. Interventions were given in the original A.R.T. study
- Where
- 3 sites in Bulgaria, Cyprus and 1 more
- Volunteers
- 455 people
- Sponsor
- FrieslandCampina
Premature Birth, Mothers of Newborn Infants
Maternal Self-efficacy and Motor Development in Premature Infants: Clinical Trial Protocol
Mothers of premature newborns face special home care situations due to the conditions of their children after hospital discharge; This requires promoting the positive perception of maternal self-efficacy and thus achieving the…
- Trial name
- NCT06420635
- Testing
- Interdisciplinary intervention program on maternal self-efficacy and the motor development of premature children, Traditional kangaroo program
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Universidad de la Sabana
Preterm Birth, Anxiety
Online Mother-Baby Yoga With Preterm Infants and Their Mothers
The purpose of this study is to examine the effects of internet-based mother-baby yoga on preterm infants and their mothers.
- Conditions
- Preterm Birth, Anxiety, Development, Infant
- Trial name
- NCT05147480
- Testing
- internet-based mother-baby yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Halic University
Cerebral Palsy, Premature Birth
Early Movements as a Predictor of Future Developmental Delay
Cerebral Palsy (CP) is a major developmental problem. Major risk groups of CP, are preterm infants and multiple pregnancies. Previous studies using the General Movements methodology demonstrated early identification of CP, as…
- Trial name
- NCT00418808
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Failure to Thrive
Trial of Home Visitation Among Infants With Failure To Thrive
1. Children in the home intervention group will have better growth (increase in weight and height) than children in the control group. 2.
- Trial name
- FTT (NCT00483691)
- Testing
- Home Visit
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Low Birth Weight Infants, Preterm Infants
Predictors and Outcomes of Kangaroo Mother Care: A Quasi-Experimental Study in Pakistan
This quasi-experimental study evaluated the impact of Kangaroo Mother Care (KMC) versus Conventional Care (CC) on the growth, developmental milestones, breastfeeding, vaccination, and mortality of low birth weight infants in…
- Trial name
- NCT06559020
- Testing
- Kangroo mother care
- Where
- Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Preterm Birth, Developmental Delay
The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years
Objective of the study: To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning,academic achievement, physical morbidities and growth of MLPTI at the age of…
- Conditions
- Preterm Birth, Developmental Delay, Growth Delay
- Trial name
- NCT05990582
- Testing
- CBCL, SDQ, CCC-2-NL
- Where
- Netherlands
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Noordwest Ziekenhuisgroep
Preeclampsia
Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development
Pregnant mothers who develop high blood pressure and other vascular problems (preeclampsia) deliver babies with increased neonatal health problems, which include lung disease and vascular complications, later in life.
- Trial name
- NCT02639676
- Testing
- Diffusion Lung Capacity (DLCO), Vascular Challenge, Video Imaging, Specimen Collections
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- Indiana University
Healthy
Hair Biomarkers Study
Young children aged 0-4 years may be exposed to adverse childhood experiences (ACEs) and/or early life adversity (ELA), which are linked with worse physical and mental health across their lifespan.
- Trial name
- HBS-II (NCT07011082)
- Testing
- Stress preventative measures
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism, Autism Spectrum Disorder
Milieu Teaching-AV: Adaptation of Milieu Teaching That Encourages Looking to the Mouth
This project will look at Milieu Teaching (i.e., a language intervention) that encourages looking to audiovisual speech cues (Milieu Teaching-AV) for infants with autistic older siblings (Baby Sibs), who are highly likely be…
- Conditions
- Autism, Autism Spectrum Disorder, Autism, Susceptibility to, 6
- Trial name
- MilieuTeach-AV (NCT07494513)
- Testing
- Milieu Teaching-AV, Milieu Teaching-NoAV
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home