Clinical trials: Infant Development
Food Allergy in Infants, Food Allergen Sensitisation
Human Breast Milk's Role in Food Allergy Development
The goal of this prospective cohort pilot study is to learn about food allergens being passed on in breast milk to breast feeding infants.
- Conditions
- Food Allergy in Infants, Food Allergen Sensitisation, Breast Feeding, Exclusive, Breastmilk Collection
- Trial name
- NCT06765213
- Testing
- Open Ended Oral Food Challenge, Early Introduction
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Preterm Infants
Effect of Reduced Noise Levels and Cycled Light on Visual and Neural Development in Preterm Infants
Noise is a hazard for newborn. In 1997, the American Academy of Pediatrics determined that safe sound levels in the neonatal intensive care unit (NICU) should not exceed 45 dB which has been rarely achieved.
- Trial name
- NCT02688010
- Testing
- Noise reduction and cycled light
- Where
- China
- Volunteers
- 109 people
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Genome Environment Microbiome and Metabolome in Autism Study
GEMMA is a multicenter longitudinal observational study that follows children who are genetically at-risk of developing autism for their first three years of life, seeking to identify potential biomarkers predictive of autism…
- Trial name
- GEMMA (NCT04271774)
- Where
- 3 sites in United States, Ireland and 1 more
- Volunteers
- 344 people
- Sponsor
- Massachusetts General Hospital
Cerebral Palsy, Developmental Delay
SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants
The study aims to develop a SmarToyGym where sensitized, wireless toys are strategically hung and placed within reach of infants to elicit toy-oriented body and arm/hand movements.
- Conditions
- Cerebral Palsy, Developmental Delay, Stroke, Fine Motor Delay
- Trial name
- NCT02813889
- Testing
- SmarToyGym
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hip Dysplasia, Developmental
Efficacy Study of DeepDDH System in Screening Infants with Developmental Dysplasia of the Hip (DDH)
To ascertain the efficacy of the DeepDDH system, a deep learning framework, in enhancing diagnostic accuracy and curtailing follow-up intervals for infants undergoing screening for developmental dysplasia of the hip (DDH), the…
- Trial name
- NCT06765525
- Testing
- Junior sonographer measurement of DDH, Senior sonographer measurement of DDH, Automated annotation of the DDH measurement through deep learning
- Where
- China
- Volunteers
- 1,976 people
- Sponsor
- RenJi Hospital
Intervention
Effect of Developmental Care on Very Low Birth Weight Infants
The goal of this clinical trial is to learn if developmental care works when implemented in very low birth weight infants. The main questions it aims to answer are: Does developmental care shorten the length of hospital stay in…
- Trial name
- NCT06515574
- Testing
- developmental care
- Where
- 2 sites in China
- Volunteers
- 1,600 people
- Sponsor
- Children's Hospital of Fudan University
Infant Development
Effect of a Mix of Dairy Lipids and Plant Oils in Infant Formula on Omega-3 Fatty Acid in Red Blood Cells
The objective of this study is to determine whether the use of a mix of dairy lipids and plant oils in infant formula can increase the sum of omega-3 fatty acids levels in membrane phospholipids of red blood cells (RBC) in 4…
- Trial name
- REBECA (NCT01611649)
- Testing
- Formula containing dairy lipids and plant oils, Formula containing plant oils, Formula containing dairy lipids and plant oils, DHA+ARA
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Lactalis
Behavior, Infant, Development, Infant
Maternal Scent and Preterm Infant Nutrition
To study the effect of maternal scent on the oral feeding, behavior and stress level of premature infants hospitalized in the Neonatal intensive care unit and to assess its potential effect on their development at 18 to 24 months.
- Conditions
- Behavior, Infant, Development, Infant, Development, Child
- Trial name
- NCT03849248
- Testing
- Maternal scent cloth
- Where
- Lebanon
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Infant, Very Low Birth Weight, Infant, Premature, Diseases
Regulation of Cerebral Blood Flow in Very Low Birth Weight Infants
Advances in newborn intensive care have lead to dramatic improvements in survival for the most premature infants-often weighing 1 pound at birth.
- Conditions
- Infant, Very Low Birth Weight, Infant, Premature, Diseases, Cerebral Hemorrhage
- Trial name
- NCT00579943
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Arkansas
Infant
Effects of Milk Fat Globule Membrane (MFGM) - Enriched Formula With Reduced Energy and Protein Content on Growth and Development
Formula-fed infants differ from breast-fed infants in the growth pattern, risk for obesity and cardiovascular diseases, neurological development and morbidity in infections.
- Trial name
- TUMME (NCT00624689)
- Testing
- Modified formula (MFGM-enriched formula with reduced energy and protein content)
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Umeå University
Nurse's Role, Infant Development
Nurse Implemented Infant-Mother Attachment Security Program
This study focuses on adapting and evaluating an attachment-based intervention program implemented by nurses in Family Health Centers (FHCs) in Turkey.
- Conditions
- Nurse's Role, Infant Development, Maternal Behavior
- Trial name
- NCT06616090
- Testing
- Nurse Implemented Infant-Mother Attachment Security Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sabanci University
Bone Marrow Failure, Osteopetrosis
Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases
This study proposes the use of a reduced intensity chemotherapy/radiation therapy regimen followed by stem cell transplantation, as compared to standard ablative chemotherapy regimens associated with stem cell transplantation, in…
- Conditions
- Bone Marrow Failure, Osteopetrosis, Fanconi Anemia, Severe Combined Immunodeficiency
- Trial name
- NCT01019876
- Testing
- Fludarabine, Cyclophosphamide, Busulfan
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Columbia University
Infant, Premature
The Impact of Implementing NIDCAP on Preterm Infants in the NICU
The purpose of this study is to evaluate the impact of the NIDCAP program of individualized patient consultation on the neurobehavioral organization of transported preterm infants in the NICU.
- Trial name
- NCT00179933
- Testing
- Newborn Individualized Assessment Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Infant Development, Preterm Birth
Auditory Environment by Parents of Preterm Infants
Data on parent-infant physical closeness and infants' auditory environment will be collected among preterm infants when they are at gestational age of 32 to 34 weeks.
- Conditions
- Infant Development, Preterm Birth, Language Development
- Trial name
- APPLE (NCT04826978)
- Testing
- Auditory environment
- Volunteers
- 116 people
- Sponsor
- Turku University Hospital
Retinopathy of Prematurity
Enteral Administration of Docosahexaenoic Acid to Prevent Retinopathy of Prematurity
The purpose of this study is to evaluate whether docosahexaenoic acid given by enteral feeding prevent retinopathy of prematurity and/or diminish its severity in preterm infants.
- Trial name
- NCT02683317
- Testing
- docosahexaenoic acid, sunflower oil
- Where
- Mexico
- Volunteers
- 110 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Malnutrition, Child, Malnutrition, Infant
Assessing the Effect of Sustainable Small-scale Egg Production on Maternal and Child Nutrition in Rural Zambia
Animal source foods (ASF), such as meat and eggs, are rich in nutrients critical for growth and development. Yet, for poor children in developing countries, ASF consumption is limited by cost, inadequate caregiver knowledge, and…
- Trial name
- NCT02516852
- Testing
- Egg production
- Where
- Zambia
- Volunteers
- 3,546 people, healthy volunteers welcome
- Sponsor
- Cornell University
Development
Sensitive Periods in Human Flavor Learning
The goals of the proposed research are to specify the timing and consequences of the sensitive period for flavor learning in infants who are being breastfed or formula fed.
- Trial name
- NCT01667549
- Testing
- Timing of Diet and Flavor Experience
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Fetomaternal Hemorrhage, Neonatal Anemia
Identification of Early Predictors of Fetomaternal Hemorrhage
Objectives: 1) To determine risk factors for fetomaternal hemorrhage. 2) To identify a cost-effective method to detect fetomaternal hemorrhage prior to significant fetal anemia.
- Trial name
- NCT01232387
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Orthopedic Disorder
Developmental Hip Dysplasia by Ultrasonographic Screening of Asymptomatic Infants at Assiut University Hospital
Developmental dysplasia of the hip (DDH), formerly known as congenital dislocation of the hip, comprises a spectrum of abnormalities that include abnormal acetabular shape (dysplasia) and malposition of the femoral head.
- Trial name
- NCT03476915
- Testing
- ultrasound examination of the hip joint
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infant Growth
Effect of a New Infant Formula With Specific Ingredients
The purpose of this study is to test whether the addition of certain bioactive ingredients to a new infant formula (HMOs, osteopontin and probiotics) can have a favorable impact on the development of the infant's immune system in…
- Trial name
- EARLY-TOLERA (NCT04306263)
- Testing
- Enriched infant formula, Standard formula, Breastfeeding arm
- Where
- Spain
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Laboratorios Ordesa