Clinical trials: Infant Developmental Assessment
Developmental Dysplasia of the Hip (DDH)
Evaluation of a Software Application for Assessment of Developmental Dysplasia of the Hip
The goal of this prospective, multicentre clinical investigation is to evaluate whether an artificial intelligence (AI)-supported software application can assist clinicians in the diagnostic assessment of developmental dysplasia…
- Trial name
- EPA-DDH (NCT07488260)
- Testing
- AI-supported hip ultrasound analysis
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pentacomp Systemy Informatyczne S.A
Other Preterm Infants
Swallowing Sound in Preterm Infant Evaluation of Feeding Maturation
Our objective was to evaluate maturation of sucking and swallowing in preterm infants using a non-invasive method: assessment of swallowing sounds. Findings in healthy term infants were used as reference values.
- Trial name
- NCT01944956
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Baskent University
Infant Formula, Estrogen Activity
Study of Infant Diets on Estrogen Activity and Development
This study, conducted at the University of Pennsylvania s Newborn Nursery, the Children s Hospital of Philadelphia, and the Exton Specialty Care Center, will examine how different infant diets may affect estrogen activity in…
- Trial name
- NCT00340665
- Where
- 2 sites in United States
- Volunteers
- 239 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Child Development
Responsive Parenting Program for Infants in Rural Bangladesh
Children of mothers in the intervention parenting program are expected to show benefits over the standard care control group in terms of better cognitive/language development, less recent illness, and better height for age.
- Trial name
- NCT01466933
- Testing
- Responsive parenting, Child Development
- Where
- Bangladesh
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- McGill University
Preterm, Motor
Investigation of the Effectiveness of Environmental Enrichment-Based Intervention in Preterm Infants
The aim of this study is to investigate the effectiveness the HEP (Homeostasis-Enrichment-Plasticity) approach, which based upon the principles of enriched environment (EE) and ecological theories of development on preterm…
- Conditions
- Preterm, Motor, Development, Infant, Therapy
- Trial name
- NCT05261503
- Testing
- HEP, Traditional Phsical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Istanbul University - Cerrahpasa
Mother-Child Relations, Preterm Birth
The 2015 Pelotas (Brazil) Birth Cohort Study
This is the fourth birth cohort to be carried out in the city of Pelotas (Brazil) including more than 4 thousand children followed-up since the pre-natal period to study maternal-child health.
- Conditions
- Mother-Child Relations, Preterm Birth, Infant Development, Breast Feeding
- Trial name
- NCT03271723
- Testing
- Observational study
- Where
- Brazil
- Volunteers
- 4,275 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Children with Developmental Risk
Investigation the Effect of the Social-Communication Area Developmental Screening Test for Infants and Young Children Training Program Applied in Addition to the DIR/Floortime™ Therapy Program in Children with Developmental Risk
The term "developmental risk" is used as a general term for developmental delays observed in infancy and early childhood. Developmental delay refers to the delay in children reaching developmental milestones compared to their…
- Trial name
- NCT06345170
- Testing
- The DIR/Floortime™ Therapy Program, The Social-Communication Area Developmental Screening Test for Infants and Young Children (SCASI) Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Biruni University
Infant Development, Safety Issues
Safety of Bifidobacterium Breve PS1 for Infants
The objective of this work was the characterization of the probiotic potential of Bifidobacterium breve PS1, a strain originally isolated from human milk.
- Trial name
- NCT05973812
- Testing
- Infant formula supplemented with Bifidobacterium breve PS1, Infant formula NOT supplemented with Bifidobacterium breve PS1
- Where
- 3 sites in Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Child Development Disorders, Preterm Infant
Reliability of Hammersmith Examination in Prediction of Neurological Outcomes (REHAPENO)
In this study workers are trying to test the correlation between Hammersmith Infant Neurological Examination and MRI brain/cranial ultrasound with early prediction of neurological developmental outcome of preterm neonates.
- Conditions
- Child Development Disorders, Preterm Infant, Cerebral Palsy
- Trial name
- REHAPENO (NCT03580252)
- Testing
- Correlation analyses for the outcomes
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Abha International Private Hospital
Asphyxia Neonatorum
Asphyxia Associated Metabolite Biomarker Investigation (AAMBI)
Verification of biomarkers in a human population for their ability to diagnose the severity of neonatal asphyxia. These biomarkers linked to asphyxia have been identified in animal studies.
- Trial name
- AAMBI (NCT03354208)
- Testing
- blood sampling
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Life Science Inkubator
Achondroplasia
Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH)
This is a Phase 2, multicenter, randomized, placebo-controlled study to evaluate the safety and efficacy of infigratinib in participants < 3 years old with ACH.
- Trial name
- NCT07169279
- Testing
- Infigratinib is provided as a single dose of minitablets for oral administration, Infigratinib is provided as sprinkle capsules for daily oral administration
- Where
- 12 sites in United States, Australia and 5 more
- Volunteers
- 77 people
- Sponsor
- QED Therapeutics, a BridgeBio company
NIDCAP
Application of the Best Evidence of Neonatal Individualized Developmental Care Assessment Program (NIDCAP) in Very Low Birth Weight Infant (VLBWI)
In order to help THE GROWTH and development of VLBWI in Neonatal Intensive Care Unit (NICU) and reduce the interference of external environment to them, we summarized the best evidence of NIDCAP care, and applied the evidence to…
- Trial name
- NCT05166720
- Testing
- NIDCAP care
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Children's Hospital of Fudan University
Sickle Cell Disease
Development and Evaluation of an Information Management System and Communication System for Population-wide Point-of-care Infant Sickle Cell Disease Screening
Although over 75% of children with sickle cell disease (SCD) are born in sub-Sahara where the disease highly contributes to under-5 mortality and causes life-long debilitation, evidence-based strategies to control SCD are not…
- Trial name
- SIMCS SCD (NCT06563440)
- Testing
- Digital app and information system
- Where
- 2 sites in United States, Uganda
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Makerere University
Premature Infant, Clustered Care
Development and Effectiveness Evaluation of a Clustered Care Guideline Within Individualized Developmental Care: RCT
The Individualized Developmental Care (IDC) model was developed to minimize the negative impact of the neonatal intensive care environment and to support infants' physiological stability.
- Conditions
- Premature Infant, Clustered Care, Neonatal Intensive Care Unit, Developmental Care
- Trial name
- Guideline (NCT07052786)
- Testing
- Infants will receive group care based on individualized developmental care according to the guide., Standard care
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Postpartum Depressive Symptoms, Breastfeeding
Mediterranean Diet on Postpartum Depression
Optimal maternal nutrition and mental well-being are important for successful breastfeeding and maternal and infant health. The objective of this randomized controlled study was to evaluate the effect of a Mediterranean diet…
- Trial name
- NCT07793864
- Testing
- Mediterranean diet, Standard nutrition information
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Eye Diseases
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases
This study will evaluate and treat children or adults with inherited or developmental eye conditions. It will allow specialists in pediatric ophthalmology, genetic ophthalmology, and ocular motility at the National Eye Institute…
- Trial name
- NCT00076271
- Where
- 2 sites in United States
- Volunteers
- 350 people
- Sponsor
- National Eye Institute (NEI)
Cerebral Palsy, Infant Development
Neuroimaging of Babies During Natural Sleep to Assess Typical Development and Cerebral Palsy
Background: Early diagnosis of cerebral palsy (CP) is crucial, enabling intervention when neuroplasticity is at its highest. Magnetic resonance imaging (MRI) plays a vital role in CP diagnosis.
- Conditions
- Cerebral Palsy, Infant Development, Development, Infant
- Trial name
- NIBS-CP (NCT06396520)
- Testing
- No intervention, observational
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Language Development
Do Video Materials Help Parents to Support Infant Development?
The aim of this project is to assess whether video materials from the BBC Tiny Happy People (THP) campaign are effective in terms of improving the language skills of socioeconomically disadvantaged children before they start…
- Trial name
- NCT04919343
- Testing
- BBC Education Tiny Happy People videos, Physical health control intervention
- Where
- United Kingdom
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Cystic Fibrosis
Development and Validation of a Disease Specific PROM to Assess Abdominal Involvement in Patients With CF (CFAbd-Score)
Development, validation and evaluation of a new multimodal questionnaire to assess and quantify the abdominal involvement in patients with the inherited life shortening multi-organ disease Cystic fibrosis.
- Trial name
- CFAbd-Score (NCT03052283)
- Testing
- Questionnaire Patient Reported Outcome Measure (PROM)
- Where
- 2 sites in Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Colic, Infantile, Motor Development
Investigation of the Development of Infants With a History of Colic
The aim of this study was to evaluate the motor development, sleep characteristics and sensory processing skills of infants with a history of colic and to compare them with their peers without a history of colic.
- Conditions
- Colic, Infantile, Motor Development, Sleep, Sensory Integration Dysfunction
- Trial name
- NCT06866249
- Testing
- Peabody Developmental Motor Scales-2, Test Of Sensory Functions In Infants (Tsfı), Brief Infant Sleep Questionnaire
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University