Clinical trials: Infant Developmental Assessment
Congenital Heart Disease in Children, Infant Development
Evaluations of Cardiopulmonary Function and Motor Development of Congenital Heart Disease
In this single-center, randomized controlled trial, patients (4-8 months) with CHD were randomly assigned to either a recovery group (home-based rehab exercise periodically) supervised by cellphone APP or to a control group.
- Conditions
- Congenital Heart Disease in Children, Infant Development, Infant Conditions, Motor Neuropathy
- Trial name
- NCT05518136
- Testing
- exercise-guidance on rehab APP
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Gejingwa Zhao
Infant and Young Child Feeding
Standardized Application of Feeding Evaluations Using SMART Tool
Premature and medically complex infants have delayed development of oral feeding skills, leading to prolonged hospitalization, costs, and family stress.
- Trial name
- SAFEST (NCT07136610)
- Testing
- SMART Tool
- Where
- 14 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Wake Forest University Health Sciences
Preterm Birth
The GROWNDUP Study of Late Preterm Births
This pilot study will examine the feasibility of conducting a large randomized clinical trial (RCT) to examine the role of a novel, specialized follow-up clinic in preventing complications among late preterm infants (LPTB), born…
- Trial name
- GROWNDUP (NCT01747603)
- Testing
- Specialized LPTB clinic
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University
Premature Newborn
Reproducibility of a New Practical Newborn Behavioral Observation Scale
Neonatal intensive care is necessary for the survival of preterm baby. Several studies show the deleterious effect on the immature brain due to stimulations caused by the environment and hospital care.
- Trial name
- NCT02844205
- Testing
- quotation of the newborn behavioral observation scale
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Infant Behavior, Gestational Age Over 30 Weeks
Influence of the Aquatic Physical Activity for the Neurologic Development of the Babies
Introduction: physical activity in infants through aquatic therapy is widely known for the later development of sensory ,cognitive and motor areas.
- Trial name
- NCT03153839
- Testing
- Aquatic physical activity in babies
- Where
- Spain
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Early Childhood Development
Evaluation of the iMBC/ECD Model in Ghana
The Duke research team will work with Catholic Relief Services (CRS) and lead the design and implementation of a cluster-randomized trial in Northern Ghana to assess the impact of the Integrated Mothers and Babies Course \& Early…
- Trial name
- NCT03665246
- Testing
- Integrated Mothers and Babies Course
- Where
- Ghana
- Volunteers
- 378 people
- Sponsor
- Duke University
Cystic Fibrosis (CF)
MRI Assessment of Lung Airways in Cystic Fibrosis: Evaluate MRI's Ability to Detect Changes in Airway Structure .
This study is being done to determine whether MRI can produce high quality lung and airway images in healthy and CF patients and if MRI can be used to evaluate size and shape of the airways with computer assistance.
- Trial name
- UTE Airway MR (NCT07454681)
- Testing
- Advanced ultrashort echo time (UTE) MRI - Ultrashort echo time (UTE) imaging is a technique that can quickly capture the fast-decaying 1H lung signal., Multiple Breath Wash out (MBW)
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Child Development
Effect of an Innovative BIO Formula Intake on Infant Growth and Tolerance From 0 to 6 Months
From birth to 5 months, milk is the essential and unique food of the newborn. The French National Nutrition Program (PNNS) recommends exclusive breastfeeding "up to 6 months and at least 4 months for a healthy benefit".
- Trial name
- TRUEGREEN (NCT03936257)
- Testing
- Breastfeeding, Conventional BIO Infant formula, TrueGreen BIO infant formula
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Growth & Development, Formula Feeding of Healthy Full Term Infants
Evaluation of Different Protein Content of Formulas on Nutrition Status of Infants.
Human milk (HM) is the gold standard of early infant nutrition. The World Health Organization (WHO) recommend that newborns be exclusively breastfed for the first 6 months of life.
- Conditions
- Growth & Development, Formula Feeding of Healthy Full Term Infants, Breast Feeding of Healthy Full Term Infants
- Trial name
- NCT03513991
- Testing
- Infant formula
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Queretaro
Infant Development
A Pilot Study Using Photo-plethysmographic (PPG) Camera
The researcher want to use video signals to monitor heart rate, respiration rate and oxygen saturation using Photo-plethysmography (PPG) as the underlying mechanism for the method: periodic changes in skin reflectance, induced by…
- Trial name
- NCT01166867
- Testing
- Photo-plethysmography monitoring
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Achondroplasia
A Clinical Trial to Evaluate Efficacy and Safety of TransCon CNP Compared With Placebo in Infants (0 to <2 Years of Age) With Achondroplasia
This trial is a Phase 2, multicenter, double-blind, randomized (ratio 2:1 TransCon CNP vs. placebo), placebo-controlled trial, designed to evaluate the safety, tolerability, and efficacy of 100 μg CNP/kg of Navepegritide…
- Trial name
- NCT06079398
- Testing
- Navepegritide
- Where
- 18 sites in United States, Australia and 13 more
- Volunteers
- 72 people
- Sponsor
- Ascendis Pharma A/S
Cholestasis in Newborn, Biliary Atresia
The Dirty Nappy Study
This observational study evaluates whether a machine-learning algorithm, a computer program that learns patterns from data, can accurately diagnose cholestasis in newborns.
- Conditions
- Cholestasis in Newborn, Biliary Atresia, Neonatal Cholestasis
- Trial name
- NCT07697872
- Where
- United Kingdom
- Volunteers
- 5,350 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Infant, Premature Birth
Massage Application and Motor Performance, Stress Assessment in Premature Babies
In our study, the effect of infant massage applied in the intensive care unit on motor performance and stress hormones in premature babies will be examined. The number of patients to participate in the study was determined as 30.
- Trial name
- NCT06075992
- Testing
- experimental group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Mustafa Kemal University
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy Infantile, Pre-Term
Motor-voice Assessment in Infants (MAMI)
The goal of this observational study is to discover features of normal and disordered motor-voice profiles that are biobehavioral markers of physical disability in infants..
- Conditions
- Cerebral Palsy Infantile, Pre-Term, Motor Delay, Neurodevelopmental Disorders
- Trial name
- MAMI (NCT06807203)
- Testing
- Behavioral observation
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Ohio State University
Infant Development, Cerebral Palsy
Families Filming Infants Learning Movement
The study objective is to improve accuracy in the early detection of neurodevelopmental impairment, especially CP, by evaluating the timepoint (in weeks post term age) that the Prechtl GMA is most useful for prediction of…
- Conditions
- Infant Development, Cerebral Palsy, Motor Disorders, Neurological Disorder
- Trial name
- FILM (NCT06278961)
- Testing
- Observational
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago