Clinical trials: Infarction
Brain Ischemia, Acute Stroke
Heart and Ischemic STrOke Relationship studY
Although cardio-embolic etiology of ischemic stroke (IS) is largely respected, there is still no clear recommendation for routine complex cardiological examination in all IS patients.
- Conditions
- Brain Ischemia, Acute Stroke, Heart Diseases
- Trial name
- HISTORY (NCT01541163)
- Where
- Czechia
- Volunteers
- 500 people
- Sponsor
- University Hospital Olomouc
MINOCA, STEMI
Retinal OCTA for Microvascular Dysfunction Evaluation and Outcome Prediction in MINOCA Patients
The aim of this study is to evaluate microvascular dysfunction through OCTA in MINOCA patients. In order to better understand the condition, OCTA will also be performed in two matched patient groups: healthy controls and ACS…
- Conditions
- MINOCA, STEMI, Normal
- Trial name
- REVEAL (NCT07055152)
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Stroke, Cerebral Palsy
Modulation of Brain Plasticity After Perinatal Stroke
Newborn stroke is the leading cause of a common type of cerebral palsy (CP) that affects thousands of Canadian children and families.
- Trial name
- PLASTIC CHAMPS (NCT01189058)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Constraint-induced movement therapy (CIMT)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Sickle Cell Disease, Sickle Cell Anemia
Stroke Prevention in Young Adults With Sickle Cell Anemia
Sickle cell disease (SCD) is the most common genetic disease, affecting about 25 million people worldwide. Approximately 150,000 Nigerian children are born each year with sickle cell disease (SCD), making it the country with the…
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Stroke, Ischemic, Silent Stroke
- Trial name
- SPIYA (NCT04808778)
- Testing
- Hydroxyurea therapy per standard care
- Where
- 2 sites in United States, Nigeria
- Volunteers
- 250 people
- Sponsor
- Vanderbilt University Medical Center
Shock, Cardiogenic
Impella in Cardiogenic Shock Registry
The purpose of the study is to evaluate the safety, efficacy and clinical usefulness of a mechanical support strategy with the impella device.
- Trial name
- Impella (NCT06007963)
- Testing
- Treatment with impella device.
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myocardial Infarction
A Clinical Evaluation of Everolimus Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION Study
This study is a prospective, randomized controlled, single blind, two-arm, multi center clinical evaluation. A total of 1500 patients will be enrolled in the study.
- Trial name
- NCT00828087
- Testing
- Everolimus Eluting Coronary Stent System, cobalt chromium balloon expandable stent ( non drug eluting stent Arm)
- Where
- 11 sites in Italy, Netherlands and 1 more
- Volunteers
- 1,504 people
- Sponsor
- Spanish Society of Cardiology
Cardiovascular Diseases, Coronary Disease
Mediators of Social Support in Coronary Disease
To determine prospectively the extent to which structural and functional aspects of social support influences 'hard' cardiac events such as death and non-fatal myocardial infarction in patients with coronary artery disease (CAD)…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00005344
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stable Angina, Unstable Angina
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
We had little experience in coronary intervention with recently introduced newer drug-eluting stent (DES) platforms, despite great anticipation, and optimal duration of dual antiplatelet therapy (DAPT) for these stent systems…
- Conditions
- Stable Angina, Unstable Angina, Non-ST Segment Elevation Myocardial Infarction
- Trial name
- HOST-IDEA (NCT02601157)
- Testing
- 3-months DAPT, 1-year DAPT
- Where
- 12 sites in South Korea
- Volunteers
- 2,173 people
- Sponsor
- Seoul National University Hospital
Myocardial Infarction
Pattern of Repeat Cardiovascular Events During Follow-up After First Diagnosed Event-MI
Recurrent myocardial infarctions (reinfarctions) can be due to recurrence at the original treatment site, the presence of untreated lesions elsewhere, or in progressive lesions.
- Trial name
- PRECLUDE-MI (NCT03099395)
- Volunteers
- 100,000 people
- Sponsor
- Uppsala University
Cardiogenic Shock, Cardiac Arrest
China Extracorporeal Life Support Registry
Extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique of providing effective cardiac and respiratory support to patients with lungs and/or heart failure.
- Conditions
- Cardiogenic Shock, Cardiac Arrest, Heart Failure, Acute Respiratory Distress Syndrome
- Trial name
- NCT04158479
- Testing
- ECMO
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Beijing Anzhen Hospital
Prevalence of Myocarditis in MINOCA Patients
Prevalence of Myocarditis in Patients Suspected Myocardial Infarction With Non-Obstructive Coronary Arteries
This study aims to determine the prevalence of myocarditis among patients suspected of having myocardial infarction with non-obstructive coronary arteries (MINOCA) and to analyze its clinical characteristics, diagnostic markers .
- Trial name
- NCT06966531
- Testing
- Coronary angiography
- Volunteers
- 148 people
- Sponsor
- Assiut University
Myocardial Infarction, Acute Myocardial Infarction
Therapy of Preconditioned Autologous BMMSCs for Patients With Ischemic Heart Disease
The purpose of the present study is to evaluate the efficacy of the preconditioned autologous bone marrow mesenchymal stem cells for patients with ischemic heart diseases.
- Conditions
- Myocardial Infarction, Acute Myocardial Infarction, Ischemic Cardiomyopathy
- Trial name
- TPAABPIHD (NCT02504437)
- Testing
- BMMSCs
- Volunteers
- 200 people
- Sponsor
- Academy Military Medical Science, China
Acute Myocardial Infarction, Pain
To Relieve Pain and Anxiety - an Intervention Study in Ambulance Services
This is an intervention study focusing on both medical and nursing questions. The study is a joint project between the Ambulance services at four cities in West Sweden and Knowledge and research centre, PreHospen at University of…
- Trial name
- NCT00792181
- Testing
- Midazolam, Course intervention - a professional development course for caregivers.
- Volunteers
- 2,800 people
- Sponsor
- Sahlgrenska University Hospital
Pontine Infarction
Effect of TDCS Combined with Intraoral Electrical Stimulation
Objective: To investigate the clinical efficacy of transcranial direct current stimulation (tDCS) combined with intraoral electrical stimulation in patients with dysphagia after pontine infarction.
- Trial name
- NCT06852040
- Testing
- Intraoral induction electrical stimulation therapy, tDCS treatment, tDCS combined with intraoral induction electrical stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xuehai Lv
Bowel Ischemia, Acute Bowel Ischemia / Infarction
Diagnosing Acute Onset Insufficient Intestinal Blood Flow (Bowel Ischemia) With a Novel CT Technique Called Dual-energy CT (DECT). This Observational Study Seeks to Evaluate Whether DECT Can Improve the Diagnosis of Bowel Ischemia and How the DECT Findings Correlate With Intraoperative Findings
The aim of this study is to evaluate the performance of dual-energy CT (DECT) in the diagnosis of acute bowel ischemia (ABI). ABI is a condition characterised by inadequate blood supply to portions of the intestine.
- Trial name
- NCT04561323
- Testing
- Dual-energy CT
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ventricular Fibrillation, Ventricular Tachycardia
Implantable Cardioverter Defibrillator (ICD) Support Groups and Veterans
In this study, we will compare the quality of life in veterans having ICD who attend the ICD support groups to those who do not.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Sudden Cardiac Death
- Trial name
- NCT00846417
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Emory University
ST Segment Elevation Myocardial Infarction
DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction
This study focuses on Cardioprotective strategies.
- Trial name
- DANAMI-3 (NCT01435408)
- Testing
- Conventional primary PCI, Ischemic postconditioning., Deferred stenting in primary PCI.
- Where
- 5 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Myocardial Infarction
Emergency Coronary Artery Bypass Graft in Acute Myocardial Infarction
A retrospective study investigating the early outcome of emergency CABG post MI in patients who were operated at Saud Al Babtain Cardiac Center.
- Trial name
- NCT04572061
- Where
- Saudi Arabia
- Volunteers
- 109 people
- Sponsor
- Saud Al Babtain Cardiac Center
Cardiovascular Disease
Does Prophylactic Coronary Artery Revascularization for High Risk Patients Reduce Long-term Risk of Mortality
Although a number of sophisticated diagnostic tests have been shown to be helpful in identifying patients at high risk for perioperative cardiac complications, no study has addressed the most important question: Should…
- Trial name
- CARP (NCT00032370)
- Testing
- Vascular surgery with best medical treatment, Coronary artery bypass grafting (CABG), Percutaneous transluminal coronary angioplasty (PTCA)
- Where
- 18 sites in United States
- Volunteers
- 510 people
- Sponsor
- US Department of Veterans Affairs
Acute Myocardial Infarction
Using Higher Cut-off Values to Diagnose Acute Myocardial Infarction in Patients With Elevated Hs-cTnT Concentrations
High-sensitive cardiac troponin T (hs-cTnT) is a cornerstone for diagnosing acute myocardial infarction (AMI). However, it is often challenging to diagnose AMI in patients with elevated hs-cTnT before a rise or fall of hs-cTnT…
- Trial name
- NCT06059079
- Testing
- No Intervention
- Where
- China
- Volunteers
- 80,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University