Clinical trials: Infection Control
Anemia
INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections
To evaluate the safety and efficacy of red blood cells (RBCs) prepared with the INTERCEPT Blood System for Red Blood Cells Pathogen Reduction Treatment (PRT) in comparison to conventional RBCs in patients who require RBC…
- Trial name
- RedeS (NCT03037164)
- Testing
- INTERCEPT Blood System for Red Blood Cells, Conventional (Control)
- Where
- 16 sites in United States, Puerto Rico and 1 more
- Volunteers
- 692 people
- Sponsor
- Cerus Corporation
Flu, Cold
Improved Immunology Outcomes Associated With Lactoferrin Fortified With HMO in Infant Formula
The goal of this interventional clinical trial is to test the effectiveness of enhancing immunity in newly born infants fed with Feihe investigational formula product containing Lactoferrin fortified with HMO.
- Trial name
- NCT06158659
- Testing
- Feihe Investigational Formula, Control Formula, Breastfeeding
- Where
- 3 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Hospital Acquired Infections
Comparative Effectiveness of Yakson Touch and a Dextrose-Sweetened Pacifier for Reducing Phlebotomy-Induced Pain in Term Neonates
To compare the effects of Yakson Touch, the Dextrose-Sweetened Pacifier, and routine care on physiological responses, pain intensity, and behavioral outcomes among term neonates undergoing phlebotomy.
- Trial name
- Yakson Touch; (NCT07788066)
- Testing
- Yakson Touch, Dextrose-Sweetened Pacifier
- Volunteers
- 2 people
- Sponsor
- RAK Medical and Health Sciences University
Hantavirus Infections
Efficacy of Methylprednisolone for Hantavirus Cardiopulmonary Syndrome
The purpose of this study is to see if a drug, called methylprednisolone, is safe and effective in people with Hantavirus infection.
- Trial name
- NCT00128180
- Testing
- Methylprednisolone
- Where
- Chile
- Volunteers
- 66 people
- Sponsor
- University of New Mexico
Mpox (Monkeypox)
Epidemiological and Clinical Characteristics of Human Mpox Outbreak in Equateur Province in the Democratic Republic of Congo (Part3)
The goal of this study is to evaluate the effectiveness of smallpox vaccination administered before the global eradication of smallpox against currently circulating mpox in the Democratic Republic of the Congo.
- Trial name
- NCT06984705
- Where
- Democratic Republic of the Congo
- Volunteers
- 144 people
- Sponsor
- Osaka Metropolitan University
Infections, Streptococcal, Streptococcus Pneumoniae Vaccines
Assess the Immunogenicity of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine
Evaluate the immune response of GSK Biologicals' 10-valent pneumococcal conjugate vaccine one month after completion of a 3-dose primary vaccination course administered at 2, 3, 4 months of age
- Trial name
- NCT00307541
- Testing
- Pneumococcal (vaccine)
- Where
- 32 sites in Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Adolescent HPV Vaccine, Adolescent Influenza Vaccine
4 Pillars Toolkit for Adolescent Vaccination
The purpose of this study is to test whether or not the 4 Pillars Immunization Toolkit increases adolescent vaccination rates, particularly influenza and human papillomavirus (HPV) but also tetanus, diphtheria and pertussis…
- Trial name
- NCT02165722
- Testing
- 4 Pillars Toolkit
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Acute Bronchiolitis
Evaluation of the Effects of Respiratory Physiotherapy in Infants With Moderate Acute Bronchiolitis
Bronchiolitis affects 460,000 children in France per year. The French study called "Bronkilib 2" found a positive effect of chest physiotherapy treatment.
- Trial name
- Bronkiville (NCT03753802)
- Testing
- Chest Physiotherapy, Surveillance
- Where
- 3 sites in France
- Volunteers
- 168 people
- Sponsor
- Réseau Kinésithérapie Bronchiolite Essonne
Osteomyelitis
Effect of Pulsed Electromagnetic Field Stimulation on Localized Pediatric Osteomyelitis
This study will be applied to evaluate effect of pulsed electromagnetic field on pediatric localized osteomyelitis.
- Trial name
- PEMF (NCT06084754)
- Testing
- pulsed electromagnetic field, Antibiotics
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Cystic Fibrosis
OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis
The purpose of this trial is to compare the effects of treatment with tobramycin solution for inhalation (TIS) with and without azithromycin in people with cystic fibrosis (CF) age 6 months to 18 years who have early isolation of…
- Trial name
- OPTIMIZE (NCT02054156)
- Testing
- azithromycin, Tobramycin solution for inhalation
- Where
- 45 sites in United States
- Volunteers
- 221 people
- Sponsor
- Bonnie Ramsey
Neonatal Infection
Experience of Mutaflor Suspension Use in Preterm Infants for Immunity Improvement
EcN has been registered as a medical drug under the brand name Mutaflor® SUSPENSION in Ukraine in 2010. Indications for its clinical use are acute diarrhea in infants and toddlers including those on tube feeding tube, diarrhea in…
- Trial name
- EMSUP (NCT01540162)
- Where
- Ukraine
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Odessa National Medical University
Failure of Dental Implant Due to Infection, Infection
Regenerative Surgical Treatment of Peri-implantitis
The purpose of the study is to evaluate if surgical treatment of peri-implantitis with enamel matrix derivative (Emdogain®, EMD) will have an additional effect on the healing outcome, changes in the peri-implant microflora and on…
- Conditions
- Failure of Dental Implant Due to Infection, Infection, Inflammation, Peri-implantitis
- Trial name
- NCT02500654
- Testing
- Emdogain®, Surgery alone
- Where
- Sweden
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Catrine Isehed
Malaria
Strengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine
The ongoing Malaria Vaccine Pilot Evaluation (MVPE) is being conducted in Ghana, Malawi and Kenya through community and sentinel hospital surveillance systems and a series of household surveys (to measure vaccine coverage).
- Trial name
- MVPE-CC (NCT05041556)
- Testing
- Case-control study of clinical outcomes, Case-control study of mortality outcome
- Where
- 4 sites in Ghana, Kenya and 1 more
- Volunteers
- 9,280 people
- Sponsor
- Kintampo Health Research Centre, Ghana
Cervical Cancers, Vulvar Cancers
A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006)
This study will evaluate whether V503 (9vHPV vaccine), is well tolerated in girls and women between 12 and 26 years old who have previously been vaccinated with GARDASIL™.
- Conditions
- Cervical Cancers, Vulvar Cancers, Vaginal Cancers, Genital Warts
- Trial name
- NCT01047345
- Testing
- V503
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Tonsillopharyngitis, Rhinopharyngitis
Trial To Assess Efficacy and Safety of PediaFlu® in Children With Acute Tonsillopharyngitis / Rhinopharyngitis
Sore throat or acute tonsillopharyngitis, often referred to as angina catarrhalis in Central and Eastern Europe, affects mainly children, adolescents and young adults and represents one of the most common reasons to consult a…
- Trial name
- NCT04899401
- Testing
- Standard of care + PediaFlù®, Standard of care
- Where
- 3 sites in Romania
- Volunteers
- 130 people
- Sponsor
- Pediatrica S.r.l
Latent Tuberculosis Infection
Risk of SDRs Under 3HP and 1HP Regimen for LTBI
Successful implement of preventive therapy for subjects with latent tuberculosis infection (LTBI) is the critical step for elimination of tuberculosis (TB).
- Trial name
- NCT04094012
- Testing
- isoniazid and rifapentine
- Where
- Taiwan
- Volunteers
- 490 people
- Sponsor
- National Taiwan University Hospital
Microbial Colonization, Tolerance
SEPSIS: L. Plantarum Trial
Sepsis is a life-threatening clinical syndrome and a leading cause of neonatal deaths worldwide. The burden of neonatal sepsis and severe infection (SI) is particularly high in areas of South Asia and other resource-limited…
- Conditions
- Microbial Colonization, Tolerance, Safety Issues, Infant ALL
- Trial name
- NCT05180201
- Testing
- Synbiotic, Probiotic
- Where
- 2 sites in Bangladesh
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Tinea Pedis
Topical Antifungal Treatment for Tinea Pedis
The purpose of this study is to determine if a topical antifungal cream is safe and effective for the treatment of tinea pedis.
- Trial name
- NCT01396811
- Testing
- 33525
- Where
- 11 sites in United States, Belize
- Volunteers
- 322 people
- Sponsor
- Medicis Global Service Corporation
Cholera
Safety and Immunogenicity of a New Formulation of Euvichol®
Number of doses and intervals: Two doses, 2 weeks apart Method of administration: Oral administration Volume of vaccine to be administered: 1.5 mL/dose Observational period: 4 weeks (2 weeks after each dose) Number of visits: 3…
- Trial name
- NCT02502331
- Testing
- Test Oral Cholera Vaccine, Euvichol®
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Neonatal Urinary Tract Infection
Suprapubic Aspiration Versus Urinary Catheterization In Neonates.
Urinary tract infection (UTI) is relatively common in infants, with an occurence rate of up to 10%. Analysis of collected urine for the presence of bacteria or fungus is the only way to make a certain UTI diagnosis.
- Trial name
- SPA (NCT01726166)
- Testing
- Suprapubic Aspiration, Urinary Catheterization
- Where
- 2 sites in Canada
- Volunteers
- 49 people
- Sponsor
- Children's Hospital of Eastern Ontario