Clinical trials: Infections, Nosocomial
Nosocomial Infections
Potential Nosocomial Infection Prevention Via Modification of Anesthesia Intraoperative Aseptic Practice
We hypothesized that by improving hand hygiene compliance in the operative environment, we would reduce horizontal transmission of pathogenic bacteria to surgical patients.
- Trial name
- NCT00617006
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Infections Nervous System, Nosocomial Infection
Infections Following NeuroSurgery (INS)
Neurosurgery (NS) is essential for the treatment of various diseases such as malignant tumors, vascular conditions, spinal stenosis or trauma.
- Conditions
- Infections Nervous System, Nosocomial Infection, Bacterial Infections, Antibiotic Resistant Infection
- Trial name
- INS (NCT03857295)
- Testing
- No interventions
- Volunteers
- 150 people
- Sponsor
- Neuromed IRCCS
Infectious Disease Transmission
Effectiveness of Chlorhexidine Bathing in the Neonatal Intensive Care Unit
This is a prospective, controlled; crossover study of daily bathing with no-rinse, 2% chlorhexidine gluconate (CHG) impregnated washcloths versus bathing with water/soap or water according to gestational age and weight (e.g.
- Trial name
- NCT02537964
- Testing
- washcloths impregnated with 2% chlorhexidine gluconate
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Shaare Zedek Medical Center
Nosocomial Infections, Bloodstream Infection
Surveillance for Nosocomial Infections in Pediatric Cancer Patients
The Oncoped 2006 study implements a multicenter prospective surveillance module for nosocomial infections in pediatric cancer patients.
- Conditions
- Nosocomial Infections, Bloodstream Infection, Invasive Aspergillosis
- Trial name
- Oncoped2006 (NCT00843804)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bonn
Infection Viral
COVID-19 - Multicenter Study on Nosocomial Transmission of SARS-CoV-2 Virus
Infection with the SARS-CoV-2 coronavirus strain is associated with severe morbidity and mortality estimated today from 2% to 4%.
- Trial name
- NOSO-COR (NCT04290780)
- Testing
- nosocomial infection/hospital acquired infection
- Where
- 2 sites in France
- Volunteers
- 2,162 people
- Sponsor
- Hospices Civils de Lyon
Ventilator Associated Pneumonia, Staphylococcus Aureus
A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2
Clinical trial looking at safety and efficacy of suvratoxumab in prevention of pneumonia caused by Staphylococcus aureus in high-risk patients
- Trial name
- SAATELLITE-2 (NCT05331885)
- Testing
- Suvratoxumab
- Where
- 27 sites in Belgium, France and 4 more
- Volunteers
- 24 people
- Sponsor
- Aridis Pharmaceuticals, Inc.
Cross Infection, Infection Control
A Randomized Trial Comparing Matt and Antimicrobial Cellomed Laminates
Sepsis contributes to nearly 20% of all hospital deaths and is the leading cause of death on non-coronary intensive care units. Contamination of the patient environment is common with organisms such as MRSA, VRE and C.difficile…
- Trial name
- NCT01245829
- Testing
- Swabbing of observation chart
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- County Durham and Darlington NHS Foundation Trust
Neonatal Sepsis
Chlorhexidine Gluconate and Alcohol Hand Rubbing on Healthcare-associated Infection
This study aims to compare of effect of chlorhexidine gluconate and alcohol hand rubbing on healthcare-associated infection (HCAI) in neonatal intensive care unit at Alexandria University Children Hospital.
- Trial name
- NCT07421323
- Testing
- Alcohol hand rub group, Chlorhexidine hand rub
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Nosocomial Infection
Administration of a Lactobacillus GG and Vitamins Containing Mixture is Effective in Preventing Nosocomial Infection in Children
Nosocomial infections are infections that occur from the time of 'entry in the hospital up to 48h after discharge. In most developed countries, the incidence of nosocomial infections in children is between 5% and 44% with the…
- Trial name
- NCT02558192
- Testing
- Lactobacillus Rhamnosus GG
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Federico II University
Nosocomial Pneumonia
Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)
This is a phase 1, open-label, non-comparative, multicenter clinical study to evaluate the safety, tolerability, and pharmacokinetics of ceftolozane/tazobactam (MK-7625A) in pediatric participants with nosocomial pneumonia (NP).
- Trial name
- NCT04223752
- Testing
- Ceftolozane/Tazobactam
- Where
- 24 sites in United States, Chile and 7 more
- Volunteers
- 41 people
- Sponsor
- Merck Sharp & Dohme LLC
Nosocomial Infection
Healthcare-Associated Infections in Ukraine and the Activity of 4-Thiazolidinone Derivatives Against Related Pathogens
The goal of this observational study is to evaluate the species spectrum and biological properties of bacterial and fungal pathogens causing healthcare-associated infections (HAIs) and to investigate the antimicrobial activity of…
- Trial name
- HAIsUA (NCT06508398)
- Testing
- Microbiological Diagnostic Testing
- Where
- Ukraine
- Volunteers
- 250 people
- Sponsor
- Danylo Halytsky Lviv National Medical University
Nosocomial Infection in Neonatal Intensive Care Unit
Bacteriological Profile and Antibiotic Sensitivity in Neonatal Intensive Care Unit at Assuit University Children Hospital
The study aims to assess the bacteriological profile and antibiotic sensitivity in NICU of pediatric hospital of assuit university.
- Trial name
- NCT06891768
- Testing
- Blood culture
- Volunteers
- 134 people
- Sponsor
- Assiut University
Brain Injuries, Congenital Heart Disease
Protecting Brains and Saving Futures - the PBSF Protocol
Background: Multiple neonatal disorders are associated with risks of neurological injury. Thus, management of these infants should involve a coordinated approach to permit early diagnosis with improved clinical care.
- Conditions
- Brain Injuries, Congenital Heart Disease, Newborn Morbidity, Intraventricular Hemorrhage
- Trial name
- PBSF (NCT03786497)
- Where
- 2 sites in Brazil
- Volunteers
- 2,268 people
- Sponsor
- Protecting Brains Saving Futures
Candidemia
Prevalence and Epidemiology of Nosocomial Candidaemia and Antifungal Susceptibility Patterns in an Italian Tertiary-Care Hospital
During the past two decades, the frequency of invasive fungal infections has increased dramatically in hospitalised patients throughout the world, and Candida has now emerged as one of the leading causes of bloodstream infections…
- Trial name
- NCT00903526
- Volunteers
- 250 people
- Sponsor
- University of Modena and Reggio Emilia
Nosocomial Infection, Diarrhea
L Reuteri for the Prevention of Nosocomial Diarrhea
Nosocomial diarrhea is any diarrhea that a patient contracts in a health-care institution. In children, it is commonly caused by enteric pathogens, especially rotavirus.
- Conditions
- Nosocomial Infection, Diarrhea, Gastroenteritis
- Trial name
- PND (NCT01046656)
- Testing
- Lactobacillus reuteri (DSM 17938)
- Where
- Poland
- Volunteers
- 106 people
- Sponsor
- Medical University of Warsaw
Nosocomial Infection
Epidemiological Investigation of CRBSI, VAP, CAUTI in Chinese ICU
The current protocol desires to implement a large-multicenter observational study of hospital acquired infection in ICU in China.
- Trial name
- NCT01943331
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Southeast University, China
Nosocomial Infection, Infection Control
Can Environmental Cleanliness be Assessed by BCA (Bicinchoninic Acid) Method
Effective cleaning of surfaces in the hospital environment is an absolute necessity to reduce pathogen transmission. Multi Drug Resistant Organisms (MDRO) in ICU are among the leading causes of hospital-acquired infections.
- Conditions
- Nosocomial Infection, Infection Control, Multi-antibiotic Resistance
- Trial name
- BCA (NCT04212130)
- Testing
- BCA method for assessing environmental cleanliness
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Infection, Bacterial, Infection Prevention
Optimising Kangaroo Care to Reduce Neonatal Severe Infection/Sepsis and Resistant Bacterial Colonisation Among High-risk Infants in NICU.
NeoDeco is a pragmatic, multicenter, parallel-group, cluster-randomised hybrid effectiveness-implementation trial designed to evaluate the impact of implementing optimised Kangaroo Care (KC) at the unit level compared to standard…
- Trial name
- NeoDeco (NCT05993442)
- Testing
- Optimised kangaroo care
- Where
- 24 sites in Greece, Italy and 3 more
- Volunteers
- 3,080 people
- Sponsor
- PENTA Foundation
Nosocomial Infection
Biosafety of Musical Instruments in the ICU
This study investigates the efficacy of the institutional disinfection protocol for musical instruments in the ICU of the music therapy service of the University Hospital Fundación Santa Fe de Bogotá (FSFB), Colombia.
- Trial name
- NCT05988853
- Testing
- follow-up of patients
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Santa Fe de Bogota
Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus
Volatile Organic Compounds in Staphylococcus Aureus Patients
The zNose® MRSA test is a non-invasive breath test for markers of Staphylococcus aureus, which may predict the probability of bacterial organisms in the anterior nares, throat and respiratory tract, wounds, and anus and therefore…
- Conditions
- Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus, Nosocomial Disease
- Trial name
- MRSAVOC (NCT01379053)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation