Clinical trials: Infertility, Male
Male Infertility
The Paleolithic Diet and Male Factor Infertility
Prospective studies concerning diet and male fertility are lacking. Observational studies suggest that a diet rich in fruits, vegetables and meats may be associated with higher sperm counts.
- Trial name
- NCT01346631
- Testing
- paleolithic diet
- Where
- Israel
- Sponsor
- HaEmek Medical Center, Israel
Genetic Disorder, Infertility
Inherited Reproductive Disorders
Background: During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. Some people have low hormone levels that severely delay or prevent puberty.
- Conditions
- Genetic Disorder, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01500447
- Where
- 2 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infertility, Infertility, Female
Developmental Epidemiological Study of Children Born Through Reproductive Technology
DESCRT will be a long-term study that both looks back in time, at successful pregnancies, and forward in time at early pregnancy and long-term as these children grow.
- Conditions
- Infertility, Infertility, Female, Infertility, Male, Infertility Primary
- Trial name
- DESCRT (NCT03799107)
- Where
- United States
- Volunteers
- 2,020 people
- Sponsor
- University of California, San Francisco
Infertility, Infertility, Female
Retrospective Study on the Use, Efficiency, and Safety of the At-home Mosie Kit
This study examines the experience of people who have selected to use the at-home insemination Mosie Kit to understand the user's experience, the perceived safety and the efficiency.
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- NCT04646291
- Testing
- Insemination with the Mosie Baby Kit
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Mosie Baby
Varicocele; Male Infertile;Varicocelectomy
The Effect and Prognosis of Different Operations on Varicocele - a Single-center Clinical Study
The purpose of this study is to determine whether high ligation of spermatic vein by open operation and microsurgery for patients with are effective in the treatment of varicocele and to determine which surgical option is better.
- Trial name
- NCT01757548
- Testing
- open operation, microsurgery
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Abnormal Spermatogenesis, Azoospermia
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility
The aim of this study was to assess meiotic recombination in primary spermatocytes, synaptonemal complex length and the correlation with chromosomal abnormalities in testicular spermatozoa from infertile men with idiopathic…
- Trial name
- NCT02339272
- Testing
- non interventional
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Igenomix
Prostate Cancer, Sexual Dysfunction and Infertility
Hormone Therapy in Treating Patients With Prostate Cancer
RATIONALE: Male hormones can stimulate the growth of prostate cancer cells. Hormone therapy using flutamide and finasteride may fight prostate cancer by reducing the production of male hormones.
- Trial name
- NCT00003323
- Testing
- finasteride, flutamide, quality-of-life assessment
- Where
- 43 sites in United States
- Volunteers
- 101 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Male Infertility
Semen Analysis and Insight Into Male Infertility
Semen analysis is the cornerstone for the valuation of the male partner in the infertile couples. This test has been standardized throughout the world through the World Health Organization (WHO) since the1970s by producing…
- Trial name
- NCT04178954
- Testing
- semen fluid analysis
- Volunteers
- 1,000 people
- Sponsor
- Batool Mutar
Testicular Injury, Oligospermia
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Testicular Injury and Oligospermia
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Testicular Injury and Oligospermia
- Trial name
- NCT05158114
- Testing
- AlloRx
- Where
- Antigua and Barbuda
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Male Infertility Due to Azoospermia
Male Factor Infertility Across India Using Aphrodite Criteria
Study Purpose: The purpose of this study is to conduct an observational cross-sectional analysis of male factor infertility across diverse regions of India utilizing the Aphrodite Criteria.
- Trial name
- APHR (NCT06911840)
- Testing
- No Intervention: Observational Cohort
- Where
- India
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- Indira IVF Hospital Pvt Ltd
Male Infertility
Can the Origin of Sperm Affect Embryo Ploidy in Patients With Severe Male Factor Infertility?
There is evidence indicating that sperm plays a role in determining blastocyst ploidy status. In our study, we aim to compare the outcomes of preimplantation genetic testing for aneuploidy (PGT-A) and the subsequent clinical…
- Trial name
- NCT06476379
- Testing
- Testicular sperm extraction (TESE), Ejaculate
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ganin Fertility Center
Infertility, Male, Cancer
Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting
Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy.
- Conditions
- Infertility, Male, Cancer, Autoimmune Disorder
- Trial name
- NCT04452305
- Testing
- Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pittsburgh
Male Infertility, Sperm DNA Fragmentation
Nordic Sperm DNA Study
Introduction The goal of this prospective observational study with an embedded randomized controlled trial (RCT) is to investigate the prevalence and clinical significance of sperm DNA fragmentation (damage to the genetic…
- Conditions
- Male Infertility, Sperm DNA Fragmentation, Lifestyle Intervention
- Trial name
- NCT07779954
- Testing
- Lifestyle change
- Volunteers
- 800 people
- Sponsor
- Regionshospitalet Viborg, Skive
Hypogonadotropic Hypogonadism, Amenorrhea
Pulsatile GnRH in Anovulatory Infertility
The purpose of this study is to explore the effects of synthetic gonadotropin-releasing hormone (GnRH) upon the pituitary and ovaries of women with infertility.
- Conditions
- Hypogonadotropic Hypogonadism, Amenorrhea, Kallmann's Syndrome
- Trial name
- NCT00383656
- Testing
- GnRH, Pump
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Massachusetts General Hospital
Azoospermia
Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia
Azoospermia due to low sperm production (non-obstructive azoospermia) affects approximately 1% of the male population and 10% of men who seek fertility evaluation.
- Trial name
- NCT02008799
- Testing
- Bone marrow stem cell injection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Man Clinic for Andrology, Male Infertility and Sexual Dysfunction
Infertility, Male
Fertility Preservation in Male AYA With Cancer
Very little is known about how medical providers can help adolescent and young adults (AYAs) and their caregivers make decisions about fertility preservation (sperm banking) before beginning cancer treatment.
- Trial name
- NCT04268004
- Testing
- FP Decision Tool and Discussion
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Leena Nahata
Endocrine Disease, Infertility
Hormonal Regulation of Puberty and Fertility
Background: The body produces gonadotropin-releasing hormone (GnRH) about every 2 hours. GnRH travels through the bloodstream to the pituitary gland, where it stimulates the gland to produce hormones called gonadotropins.
- Conditions
- Endocrine Disease, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01511588
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Cancer, Infertility
Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes
In the past two decades, evidence-based knowledge on the prevalence and risk factors for fertility impairment, including infertility, following cancer and numerous cancer treatment regimens has significantly increased.
- Conditions
- Cancer, Infertility, Late Effects, Female Fertility
- Trial name
- Follow-AYA (NCT07622537)
- Volunteers
- 4,000 people
- Sponsor
- Karolinska Institutet
Infertility Unexplained, Oligospermia
Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia
- Trial name
- infertility (NCT06342856)
- Testing
- co enzyme Q10 , L- Carnitine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Male Infertility
Vitamin D Level vs Semen Parameters
Infertility is defined as the inability of a sexually active couple to conceive after 1 year of regular intercourse without contraception, affects approximately 15% of couples, and male factors are the cause in 20% -50% of cases.
- Trial name
- NCT03167008
- Testing
- semen sample, blood sample
- Volunteers
- 60 people
- Sponsor
- Assiut University