Clinical trials: Inflammatory Markers
Sepsis
Algorithm for Predicting the Unfavorable Course of Sepsis in Children
A comprehensive strategy will be used to investigate the relationship and correlation between 4 diagnostically significant markers relevant for early diagnosis and prediction of complications and death in the development of…
- Trial name
- NCT05908162
- Testing
- Bood leukocyte subsets
- Where
- Belarus
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- The Republican Research and Practical Center for Epidemiology and Microbiology
Lifestyle-related Condition, Overweight and Obesity
Study of Omega-3 Fatty Acids Regarding Ergogenic, Anti-inflammatory and Obesity Inhibitory Effects in 8 Year Old Children
This study hypothesizes that supplementation of omega-3 fatty acids (OM3) can increase physical activity, inhibit rapid gain in body weight and BMI in both sedentary and normally active 8 year old children.
- Conditions
- Lifestyle-related Condition, Overweight and Obesity, Essential Fatty Acid Deficiency
- Trial name
- STOPP-8 OM3 (NCT01323283)
- Testing
- Omega-3
- Where
- Sweden
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Systemic Sclerosis
Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension
Although the aetiology of SSc-PAH remains elusive, vascular dysfunction seems to be the initial event and statins through their vasculoprotective effect might be of value in the treatment armamentarium of PAH related to SSc.
- Trial name
- NCT00984932
- Testing
- Rosuvastatin
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Molar-Incisor Hypomineralization (MIH)
Assessment of Peridontal Inflamatuar Markers in MIH
The goal of this observational study is to investigate periodontal inflammatory mediators in systemically healthy children aged 8-13 years with and without molar-incisor hypomineralization (MIH) who require initial periodontal…
- Trial name
- NCT07701642
- Testing
- Initial periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Marmara University
Crohn's Disease
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease
Background VSL#3 has been reported as an effective adjuvant therapy both in inducing and maintaining remission in pediatric patients affected by Ulcerative Colitis.
- Trial name
- NCT01632462
- Testing
- VSL#3
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federico II University
Obstructive Sleep Apnea Syndrome
Inflammatory Markers in Infants With Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is a common disorder in children (2-3%). OSAS in turn, is associated with significant behavioral, learning, and heart problems.
- Trial name
- NCT01058590
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Preoperative Anxiety, Emergence Agitation
Association of Inflammatory Markers With Preoperative Anxiety and Agitation
This study was planned as a prospective, observational study. The study will include pediatric patients aged 3-12 who will undergo surgery.
- Trial name
- NCT06648122
- Testing
- laboratory results
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cukurova University
ALLERGIC ASTHMA
A Description of Inflammatory Cell Types In Moderate to Severe Pediatric Asthma: Eosinophilic and Non Eosinophilic Sputum Markers While on Anti-IgE Therapy
The researcher proposes to assess levels of sputum inflammatory markers (eosinophils, eosinophil cationic protein (ECP), neutrophils IL-8) before and while on anti-IgE therapy in a pediatric population of moderate to severe…
- Trial name
- NCT00283504
- Testing
- ANTI-IGE THERAPY (XOLAIR)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of The King's Daughters
Neonatal Sepsis, Markers
Tissue Doppler Echocardiographic Assessment of Cardiac Function in Neonatal Sepsis
1. To assess myocardial function in neonates with sepsis using tissue doppler echocardiography. 2. To assess sepsis induced cardiac dysfunction. 3.
- Trial name
- NCT07572916
- Testing
- cardiac troponin, and blood culture
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Asthma, Healthy
Inflammatory Markers in Exhaled Breath (Condensate) in Childhood Asthma
Background: Exhaled nitric oxide and inflammatory biomarkers in exhaled breath condensate may be useful to diagnose and monitor childhood asthma.
- Conditions
- Asthma, Healthy, Children
- Trial name
- NCT00404976
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Vitamin D on Tumor Response and Inflammatory Markers, Colo-rectal Cancer
Evaluation the of Role of Vitamin D Supplement on Tumor Response, Inflammation and Apoptosis in Patients With Stage II or III Colorectal Cancer Receiving Chemotherapy.
The aim of this work is to assess the of role of Vitamin D supplement on tumor response, inflammation and apoptosis in patients with stage II or III colorectal cancer receiving chemotherapy using BAX protein and Tumor necrosis…
- Trial name
- NCT07241247
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tanta University
Periodontal Disease, Preterm Birth
Periodontal Disease and Preterm Birth
To determine the relationship between periodontal disease and upper genital tract inflammation in pregnancy. To determine whether certain fluid levels in the oral cavity and the vagina are associated with preterm birth or…
- Conditions
- Periodontal Disease, Preterm Birth, Low Birth Weight
- Trial name
- NCT00582374
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Malaria
Markers of T Cell Suppression: Associations With Malaria Infection and Antimalarial Treatment in Malian Children
Background: The disease malaria can cause very serious health problems. Researchers want to see if malaria affects the way T cells and vaccines work in the body.
- Trial name
- NCT02504918
- Where
- Mali
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Body Composition, Obesity
Fetal Programming of Immune Response and Body Fat by Maternal Obesity
According to the Chilean National Health Survey 2009-2010, 60% of woman in reproductive age are overweight or obese with detrimental consequences on women as well as offspring´s health at long term.
- Trial name
- EpiFat (NCT04249635)
- Testing
- DHA
- Where
- Chile
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Acute Appendicitis
Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology
The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis
- Trial name
- NCT06834958
- Testing
- Appendectomy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bone Growth Abnormal, Inflammation
Effects of Increased Greek Yogurt Consumption in Youth and Young Adult Athletes
Physical activity and dairy consumption during growth and development are each known to improve peak bone mass in young adults. Peak bone mass, the maximum amount of bone a person will have in their lifetime, is typically reached…
- Trial name
- NCT05922462
- Testing
- Greek yogurt, Whey protein
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brock University
Sepsis, Necrotizing Enterocolitis
Circulating Markers in Preterm Infants With Perinatal and Neonatal Inflammation
Circulating markers to diagnose complications (sepsis, necrotizing enterocolitis) in preterm infants are often inaccurate, partly due to the lack of comprehensive studies with temporal evaluation from birth until a disease onset.
- Conditions
- Sepsis, Necrotizing Enterocolitis, Chorioamnionitis, Feeding Intolerance
- Trial name
- NEOINFLAM (NCT03320785)
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Per Torp Sangild
Cystic Fibrosis
Non-Invasive Biomarkers in Cystic Fibrosis
Background Chronic airway inflammation is present in cystic fibrosis. Non-invasive inflammometry may be useful in disease management.
- Trial name
- NCT00413140
- Where
- 4 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Asthma
Inflammatory Markers in Exhaled Breath Condensates From Asthmatic Patients
This study aims to compare the inflammatory mediators in exhaled breathe condensates from allergic and non-allergic asthmatic patients.
- Trial name
- NCT01246414
- Where
- Thailand
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Rheumatoid Arthritis AND Apical Periodontitis
Effect of Endodontic Treatment on Inflammatory Markers, Disease Activity and Periapical Healing in Rheumatoid Arthritis Patients With Apical Periodontitis : A Prospective Interventional Study
SUMMARY TITLE: "Effect of endodontic treatment on inflammatory markers, disease activity and periapical healing in rheumatoid arthritis patients with apical periodontitis" RATIONALE: Chronic inflammation plays a pivotal role in…
- Trial name
- NCT06433232
- Testing
- ROOT CANAL TREATMENT
- Where
- India
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak