Clinical trials: Inflammatory Rheumatism
Rheumatic Heart Disease
Speckle Tracking for Timing of Surgical Operation in Severe Mitral Regurge
Rhumatic heart disease patients with mitral regurge untile know had adibat for timming of surgical interferance our study aim to solve this problme using a new technic in echocardiography called speckle tracking which is more…
- Trial name
- NCT03156972
- Testing
- Replacment of mitral valve
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohammed mahmoud mohammed othman
Active Juvenile Psoriatic Arthritis
Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis
The study will aim to estimate the efficacy of apremilast compared with placebo in the treatment of juvenile psoriatic arthritis (JPsA) in pediatric participants 5 to less than 18 years of age.
- Trial name
- PEAPOD (NCT04804553)
- Testing
- Apremilast
- Where
- 44 sites in Belgium, France and 12 more
- Volunteers
- 60 people
- Sponsor
- Amgen
Scabies, Impetigo
Evaluation of a Regional Healthy Skin Program in Remote Aboriginal Communities of Australia's Northern Territory
The purpose of this study is to determine whether a coordinated regional approach to healthy skin programs in six remote Aboriginal communities can demonstrate, not only a reduction in the burden of scabies and streptococcal skin…
- Conditions
- Scabies, Impetigo, Pyoderma, Streptococcal Infections
- Trial name
- EAHSP (NCT00884728)
- Where
- Australia
- Volunteers
- 2,329 people
- Sponsor
- Menzies School of Health Research
Rheumatic Diseases
Characterization of Adalimumab Concentrations in Pediatric Patients With Inflammatory Rheumatic Disease With and Without Methotrexate
This study is to assess standardized Adalimumab (ADA) concentrations in Pediatric inflammatory rheumatic diseases (PiRD) patients treated with ADA for ≥ 12 weeks with and without concomitant methotrexate (MTX) therapy and to…
- Trial name
- ADA in PiRD (NCT04042792)
- Testing
- pharmacokinetics (PK) measurement
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 28 people
- Sponsor
- University Hospital, Basel, Switzerland
Rheumatic Heart Disease in Children
Multi-country Evaluation of Early RHD in Children Across Africa for Vaccine Trial Readiness
This study will look at how many children develop rheumatic heart disease (RHD) over a 3-year period. The study will include children ages 5 to 8 who do not have RHD at the start and who live in areas where the disease is common.
- Trial name
- MEERCATS 1 (NCT07790302)
- Where
- Uganda
- Volunteers
- 7,500 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Juvenile Idiopathic Arthritis, Diabetes type1
Host-microbiota-environment Interactions
Two types of inflammatory and autoimmune diseases (excluding monogenic diseases) can be distinguished in children: those similar to adult diseases but with an early onset (type 1 diabetes, inflammatory diseases of the…
- Conditions
- Juvenile Idiopathic Arthritis, Diabetes type1, Inflammatory Bowel Diseases
- Trial name
- MIP-1 (NCT05176795)
- Testing
- Stool sample
- Where
- France
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Rheumatic Heart Disease in Children, Latent Rheumatic Heart Disease
Determining the Impact of Penicillin in Latent RHD: The GOAL Trial
Rheumatic heart disease (RHD) affects at least 32.9 million people, mostly children living in low-resource settings. Long-term intramuscular benzathine penicillin G (BPG) prophylaxis is proven to prevent progression of chronic…
- Conditions
- Rheumatic Heart Disease in Children, Latent Rheumatic Heart Disease, Rheumatic Heart Disease, Heart Diseases
- Trial name
- GOAL (NCT03346525)
- Testing
- intramuscular benzathine penicillin G (BPG) prophylaxis
- Where
- Uganda
- Volunteers
- 807 people
- Sponsor
- Children's National Research Institute
Sars-CoV2, Chronic Inflammatory Rheumatism
Covid-19 in Patients With Chronic Inflammatory Rheumatism, Auto-immune or Auto-inflammatory Rare and Non-rare Diseases
Since December 2019, an international outbreak of respiratory illnesses caused by SARS-CoV-2 called covid-19 has become a global challenge.
- Conditions
- Sars-CoV2, Chronic Inflammatory Rheumatism, Autoimmune Diseases
- Trial name
- covid19 fai2r (NCT04353609)
- Where
- France
- Volunteers
- 13,770 people
- Sponsor
- University Hospital, Lille