Clinical trials: Injection Pain
Unequal Length of Limbs; Congenital, Lower Extremity Deformities, Congenital
Botox Injection for Lower Extremity Lengthening and Deformity Correction Surgery
The purpose of this six site multi-center study is to determine if BTX-A can alleviate the post-operative pain and improve the functional and quality of life outcomes of children with limb length discrepancy or angular deformity…
- Trial name
- BOLLD (NCT00412035)
- Testing
- Botulinum toxin A injection, saline injection
- Where
- 6 sites in United States, Canada
- Volunteers
- 125 people
- Sponsor
- Shriners Hospitals for Children
Local Anesthesia, Dental Anesthesia
Effect of Pre-Warming of Local Anesthesia in Reducing Pain Perception During Injection in Children
The aim of the current study was to evaluate the pain perception upon injection of pre-warmed dental anesthetic solution (at 370C and 400C) versus that at room temperature (Average 23 degrees) during Maxillary Infiltration and…
- Trial name
- NCT06519838
- Testing
- Local anesthesia solution at room temperature, Local anesthesia solution pre-warmed to 37°C, Local anesthesia solution pre-warmed to 40°C
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Andrew Emad
Anterior Cruciate Ligament Reconstruction
Study of Pain Management Techniques Following Anterior Cruciate Ligament Repair Surgery
Patients scheduled to undergo knee arthroscopy with anterior cruciate ligament repair with graft from the ipsilateral hamstrings and gracilis will be randomized to one of three groups.
- Trial name
- NCT01868282
- Testing
- Hamstrings block, Obturator block, Control group
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain
Effect of the DentalVibe Injection System on Pain During Local Anesthesia Injections in Children
Title: Effect of the DentalVibe injection system on pain during local anesthesia injections in children. Purpose: The purpose of this study is to compare self-reported pain scale measurements using the Wong-Baker FACES pain…
- Trial name
- NCT03374982
- Testing
- DentalVibe
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Nebraska
Coronary Heart Disease, Angina Pectoris
Safety Study of Kudiezi (a Chinese Medicine Injection) Used in Hospitals in China
This study was advocated by Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences in October 2011.
- Trial name
- RSCMI-Ⅱ (NCT01612559)
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Injection Pain, Local Anesthesia Infiltration
Clinical Trial Comparing Pain Perception in Children Using Two Different Local Anesthesia Tools
The goal of this clinical study is to learn whether the Super Pen (SP) device can reduce pain during local anesthesia (LA) infiltration for primary teeth compared to the conventional syringe (CS) in children aged 6-12 years.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pediatric Patient
- Trial name
- NCT07292194
- Testing
- super pen
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Lamis D. Rajab
Atopic Dermatitis, Pain
Virtual Reality for Pain Management During Dupilumab Injection
The aim of this within-subject randomized study is to examine the efficacy of a VR immersive game for pain and anxiety management of children during the subcutaneous injection of dupilumab for moderate to severe atopic…
- Conditions
- Atopic Dermatitis, Pain, Anxiety
- Trial name
- VR-DERMA (NCT06182436)
- Testing
- Virtual Reality Distraction, Standard Treatment
- Where
- 2 sites in Canada
- Volunteers
- 98 people
- Sponsor
- St. Justine's Hospital
Acute Pain, Pain, Postoperative
Supraclavicular Blocks for Post-Operative Pain Control in Supracondylar Fracture Fixation, a Retrospective Analysis of Single Shot Catheter Techniques
We hypothesize that patients who receive a supraclavicular block via Angiocath, placed intra-operatively and dosed post-operatively following neurologic examination, will have lower pain scores, lower use of intravenous morphine…
- Trial name
- NCT02210429
- Testing
- Elbow Fracture Fixation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Anesthesia, Dental
Using Anesthetic Gel Patches to Reduce Pain of Palatal Injection
Local anesthetic administration step is mandatory step for controlling pain before dental procedures. The aim of this study was to compare effectiveness of topical Benzocaine 18% gel patch form and Benzocaine 20% topical gel in…
- Trial name
- NCT04317508
- Testing
- Topicale GelPatch (Benzocaine 18%), Benzocaine oral gel 20%
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Dina Youssef Attia
Postoperative Pain
Pain Control of Thoracoscopic Major Pulmonary Resection
The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.
- Trial name
- NCT01758809
- Testing
- Pre-emptive bupivacaine wound infiltration, intravenous patient controlled analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Obesity
Injection Site Pain Comparison of Excipient Solutions
The purpose of this study is to investigate different solutions used to inject drugs under the skin. The solutions used in the study do not contain the drugs they will be used for, but they do contain excipients, which are…
- Trial name
- NCT04482725
- Testing
- Trial product 1, Trial product 2, Trial product 3
- Where
- Netherlands
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Pain, Acute, Fear
The Effect of Puppet Show on Pain and Fear During Subcutaneous Injection in Children With Leukemia
This study aim to evaluate the effect of puppet show applied during subcutaneous injection to children aged 3-7 years with leukemia on the level of pain and fear experienced by children due to the intervention.
- Trial name
- SC-puppet (NCT06013501)
- Testing
- puppet show
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Local Anesthesia Infiltration
Efficacy of Facial Massager in Reducing Intra Oral Injection Pain in Pediatric Patients
Abstract Background: Local anesthesia is a primary source of anxiety in pediatric dentistry. Objective: To evaluate if mechanical vibration from a low-cost facial massager reduces pain and anxiety during injections using the Gate…
- Trial name
- NCT07682181
- Testing
- Facial T massager, Topical Benzocaine 20%
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Hospital, India
Post-mastectomy Pain Syndrome, Myofascial Pain Syndrome
Trigger Point Injections for Post-Mastectomy Pain Syndrome
Post-Mastectomy Pain Syndrome (PMPS) is a chronic pain that persists for more than three months after a surgical breast procedure. It has 11-70% incidence in patients that underwent a breast surgery.
- Conditions
- Post-mastectomy Pain Syndrome, Myofascial Pain Syndrome, Trigger Point Pain, Myofascial, Breast Cancer
- Trial name
- NCT04267315
- Testing
- Trigger point injection, Subcutaneous saline injection, Comprehensive Rehabilitation program
- Where
- 2 sites in Brazil
- Volunteers
- 72 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Diabete Type 1, Diabetes in Children
Buzzy and TickleFlex in Reducing Insulin Injection Pain and Fear
This interventional randomized controlled clinical trial aims to evaluate the effectiveness of two nonpharmacological devices, Buzzy and TickleFlex, in reducing pain and fear associated with insulin injections among children with…
- Trial name
- NCT07239700
- Testing
- Buzzy, TickleFlex, None (Routine Care)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hakkari Universitesi
Anxiety, Dental
Comparative Evaluation Between the Effectiveness of Vibration Assisted Syringe and Conventional Syringe
The study will be conducted to evaluate the effect of the vibration assisted syringe on pain perception and anxiety in children during intra oral injection of local anesthesia in comparison with conventional syringe.
- Trial name
- NCT04215055
- Testing
- vibraject
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Blind Painful Eye, Refractory Glaucoma
Use of Intravitreal Triamcinolone and Retrobulbar Chlorpromazine as Alternatives to the Management of Painful Blind Eye
The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of ocular pain in blind eyes.
- Conditions
- Blind Painful Eye, Refractory Glaucoma, Control of Pain Through Drug Injection
- Trial name
- NCT01404364
- Testing
- Triamcinolone, Chlorpromazine
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Hospital Governador Celso Ramos
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pediatric Anesthesia, Low Level Laser Theraphy
Efficacy of Low Level Laser Therapy on İnjection Pain
The purpose of this study was to compare the pain during needle insertion and injection in supraperiosteal anesthesia with either topical anesthesia (control) or LLTT (experimental).
- Trial name
- NCT04243811
- Testing
- Diode Laser, topical anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Okan University