Clinical trials: Injuries, Spinal Cord
Spinal Cord Injuries
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for SCI
This trial will study the safety and efficacy of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Spinal Cord Injury.
- Trial name
- NCT05152290
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Spinal Cord Injury
The Effect of an Exercise Program on Physical Function After a Spinal Cord Injury
This study would focus on adding a group exercise program to the usual therapy delivered in the hospital. We propose to design an exercise program that would be 30 minutes in length, 3 times per week.
- Trial name
- NCT00535210
- Testing
- Cardiovascular training, Balance training
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Spinal Cord Injury
Eyegaze Systems for Spinal Cord Injury: A Feasibility Study
As technologies are advancing quickly in the healthcare setting, new solutions have become available helping disable people to enhance their ability to communicate.
- Trial name
- NCT01943656
- Testing
- Tobii™ Eyegaze System
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Buckinghamshire Healthcare NHS Trust
Spinal Cord Injury Cervical, Spinal Cord Injury, Acute
Upper Limb Rehabilitation Using Non-invasive Spinal Cord Stimulation
The goal of this RCT study is to evaluate if combining activity-based therapy (ABT) with transcutaneous spinal cord stimulation (tSCS) can improve recovery of arm and hand movement in people with cervical spinal cord injury…
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury, Acute, Spinal Cord Injury (Quadraplegia)
- Trial name
- CIME_upperlimb (NCT07361627)
- Testing
- Protocol 2: Combination of activity-based therapy and facilitatory transcutaneous spinal cord stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Spinal Cord Injuries, Rehabilitation
Feasibility of Home-Based Rehabilitation on Body Composition, Some Anthropometric Measures and Muscular Strength After Interruption 4-5 Years of Spinal Cord Injury: Serial Cases Study on ISIS War Survivors in Iraq
Feasibility of Home-Based Rehabilitation on Body Composition, some Anthropometric Measures and Muscular Strength after interruption 4-5 years of Spinal Cord Injury: Serial Cases Study on ISIS War Survivors in Iraq Summary…
- Conditions
- Spinal Cord Injuries, Rehabilitation, Exercises
- Trial name
- HBRP-SCI (NCT06230627)
- Testing
- Home-Based Rehabilitation rogram
- Where
- Tunisia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Respiratory Support
The ACCESSIT Study
The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord injury.
- Trial name
- ACCESSIT (NCT05207046)
- Testing
- Mechanical Ventilation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Spinal Cord Injuries
NeuroSuitUp: Neurorehabilitation Through Synergistic Man-machine Interfaces
NeuroSuitUp is a multidisciplinary neurophysiological \& neural rehabilitation engineering project, developed by the Lab of Medical Physics \& Digital Innovation, School of Medicine, Faculty of Health Science Aristotle University…
- Trial name
- NeuroSuitUp (NCT05465486)
- Testing
- Brain-Computer Interface control of robotic arms with augmented reality, Serious game with augmented reality
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Spinal Cord Injury
Baseline Cardiovascular Measurements in Pediatric Spinal Cord Injury
Following spinal cord injury (SCI), the body loses normal control of blood pressure and heart rate, and there is a risk of sudden and dangerous increases in blood pressure, namely, autonomic dysreflexia (AD).
- Trial name
- NCT01599455
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Shriners Hospitals for Children
Neuromuscular Disease
Therapeutic Riding and Neuromuscular Disease
The purpose of this current prospective study is to assess the effects of a Therapeutic Riding exercise program conducted in patients suffering from neuromuscular disease.
- Trial name
- TR NMD (NCT01621984)
- Testing
- Therapeutic Riding/ Hippotherapy Intervention
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Ioannina
Spinal Cord Injury
Functional Electrical Stimulation (FES) Cycling for Children With Spinal Cord Injuries (SCI)
The overall objective of this research project is to examine the clinical efficacy of lower extremity cycling with functional electrical stimulation to improve the health and fitness of children with spinal cord injuries (SCI).
- Trial name
- NCT00245726
- Testing
- FES Cycle, ES therapy, Passive (Motor Assist) Cycle
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Shriners Hospitals for Children
Spinal Cord Injuries
Neural Facilitation of Movements in People With SCI
Spinal cord injury leads to long-lasting paralysis and impairment. Re-enabling movement of paralyzed areas is challenging and more information is needed about neurological recovery.
- Trial name
- NCT05354206
- Testing
- Electrophysiology assessment - corticospinal tract, Electrophysiology assessment - reticulospinal tract, Training with some stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Injury, Spinal Cord
Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
This is a randomized, controlled, single-blind, multicenter, two Arm (Treatment or "Scaffold" Arm; Standard of Care or "Comparator" Arm) of a Neuro-Spinal Scaffold to evaluate whether the Scaffold is safe and demonstrates…
- Trial name
- INSPIRE 2 (NCT03762655)
- Testing
- Neuro-Spinal Scaffold
- Where
- 16 sites in United States
- Volunteers
- 20 people
- Sponsor
- InVivo Therapeutics
Injuries, Spinal Cord
Clinical Trial to Evaluate One-to-one Peer Mentoring
The research will examine the effects of enhanced peer mentor interactions on facilitating a successful transition to community living following traumatic spinal cord injury (SCI).
- Trial name
- NCT02274649
- Testing
- one-to-one peer mentoring, general peer support
- Volunteers
- 194 people
- Sponsor
- Shepherd Center, Atlanta GA
Spinal Cord Injuries
Caring for Caregivers: Supporting Caregivers of Youth With Spinal Cord Injury
The current study will implement and evaluate a multi-component, psychoeducational intervention for caregivers of children with spinal cord injury (SCI) ages 7-12. Two hypotheses will be tested.
- Trial name
- NCT02083601
- Testing
- Parent Forum, Psychological support
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Erin Hayes Kelly, PhD
Scoliosis
Effectiveness of Bracing in Preventing Scoliosis in Children With Spinal Cord Injury
The purpose of this study is to determine whether full-time high dose prophylactic bracing (23 hours or more per day) is more effective than low dose bracing (12 hours or less per day) in preventing or delaying spinal curve…
- Trial name
- NCT00256672
- Testing
- Thoraco-Lumbar-Sacral-Orthoses (TLSO) / Flex-Foam
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Shriners Hospitals for Children
Spinal Cord Injuries (SCI), Urinary Retention
Clinical Trial of Abdominal Breathing for Urinary Retention After Spinal Cord Injury
Randomized controlled trials were conducted in patients with urinary retention after spinal cord injury. The effects of abdominal breathing training on pelvic floor muscle tone, muscle strength and residual urine volume in…
- Trial name
- NCT06964256
- Testing
- Abdominal breathing exercises, Control group: intermittent catheterization, Experimental group: intermittent catheterization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University
Stroke, Spinal Cord Injury
Computer Game-based Exercise Program Targeting Manual Dexterity for People With Spinal Cord Injury or Stroke.
Recovery programs of the upper extremity can be extensive, for many adults with neurological disorders/injuries, including maintenance exercises that need to be done continually to maintain function and to prevent secondary…
- Trial name
- NCT05071885
- Testing
- games based exercise
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Manitoba
Spinal Cord Injury, Stroke
Control of Unsupported Paraplegic Standing
The study will investigate the feasibility of using functional electrical stimulation (FES) of the calf muscles of paraplegic subjects to assist in posture stabilisation during standing.
- Trial name
- NCT00204113
- Testing
- Multi-purpose rehabilitation frame, Surface Functional Electrical Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Glasgow
Spinal Cord Injury, Osteoporosis
Early Intervention to Reduce Bone Loss After Spinal Cord Injury
After a complete spinal cord injury (SCI), the patient becomes wheelchair-dependent, and the associated lack of weight-bearing and inactivity of paralysed muscles can lead to extensive bone loss in the long bones of the legs.
- Trial name
- NCT02334410
- Testing
- Whole body vibration (WBV)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Strathclyde
Tethered Cord, Chiari I Malformation
Magnetic Resonance Imaging of the Spine
Diffusion-weighted (DW) magnetic resonance imaging (MRI) imaging is a well established method for detecting acute injury to the brain and is used on all children undergoing an MRI brain scan at Children's Healthcare of Atlanta.
- Trial name
- MRIS (NCT01382290)
- Testing
- MRI
- Where
- United States
- Sponsor
- Children's Healthcare of Atlanta