Clinical trials: Injuries
Hypothermia
Hypothermia in the Trauma Patient - When do Trauma Patients Get Cold?
The purpose of this study is to analyze changes in core body- and skin temperature during pre-hospital and early in-hospital treatment of multi-traumatized patients.
- Trial name
- NCT01006837
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Traumatic Brain Injury
MLC901 for Moderate to Severe Traumatic Brain Injury (Specified Drug Code)
Patients with a diagnosis of moderate to severe traumatic brain injury (TBI) will be enrolled. Subjects will be randomly assigned to receive either MLC901 (Specified Drug Code) or placebo capsules three times per day over 6…
- Trial name
- MLC901 (NCT04487275)
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Ali Amini Harandi
Cardiotoxicity, Pediatric Cancer
Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity.
- Conditions
- Cardiotoxicity, Pediatric Cancer, Heart Failure
- Trial name
- CATCH-HF (NCT04262830)
- Testing
- Cardiac magnetic resonance imaging (MRI), Accelerometer physical activity monitoring
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Hari Narayan
CerebroSpinal Fluid (CSF) Leak
The Freiburg Registry on SpontanEous IntercrAnial Hypotension (SIH) & Post-duraL Puncture Headache (PDPH)
Spinal CSF leaks are considered as rare disease. They cause a variety of symptoms, mainly culminating in a chronic headache syndrome. Crucially, yet often disregarded, the disease holds the potential for cure.
- Trial name
- SEAL (NCT06711731)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University Hospital Freiburg
Traumatic Brain Injury, Coagulation Disorder
Evaluating the Use of Thromboelastography to Diagnose Coagulopathy After Traumatic Brain Injury
The investigators will obtain thromboelastography (TEG) on pediatric patients admitted to the Rady Children's Hospital ICU after traumatic brain injury on admission to our ICU and after 24 hours of care.
- Trial name
- NCT01589172
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Skin Wound
To Evaluate The Skin Closure Time, Parents' Satisfaction, Post Operative Mental Health, Wound Cosmesis and Wound Complication Of Skin Closure Using Adhesive Glue, Adhesive Tape And Suture In Paediatric Surgery Patients
This study is a randomised controlled trial to evaluate the skin closure time, parents' satisfaction, post operative mental health, wound cosmesis and wound complication of skin closure using adhesive glue, adhesive tape and…
- Trial name
- NCT06713772
- Testing
- Dermabond Mini, 0.36ml, Ethicon Johnson and Johnson, Somerville, New Jersey, USA, Steri-StripsTM (3M, St. Paul, Minnesota, USA, Monosyn, B.Braun, 118 Pfieffewiesen, Melsungen, Germany
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
Brain Concussion, Post-Concussion Symptoms
Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery
This study is part of a larger, multi-centered project done with the collaboration of University Of Victoria. This study holds three separate studies on the mild traumatic brain injured population and the use of…
- Conditions
- Brain Concussion, Post-Concussion Symptoms, Concussion
- Trial name
- NCT03213730
- Testing
- 3D-MOT Neurotracker, Visual Attention Intervention
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sport Injury
Comparing VR and Balance Exercises In Rehabilitation of Adolescent Athletes
Ankle sprains are common injuries in active young people. Most of these injuries recovery quickly on their own, do not require imaging, and do better with early motion and rehabilitation.
- Trial name
- NCT04592900
- Testing
- balance exercising
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Valley University
Fingertip Amputation, Finger Injuries
Semi-occlusive Dressing for Pediatric Fingertip Amputations
The aim of this prospective cohort study is to assess the outcome and pain progression of fingertip (partial) amputations treated with a semi-occlusive wound dressing (regular care) in childhood and adolescence.The main questions…
- Trial name
- NCT07552753
- Testing
- semi-occlusive dressings
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Medical University of Graz
Hip Injuries
Capsular Repair in FAI Impingement Surgery
The Investigator's hypothesis is that capsular repair (after CAM or mixed Femoroacetabular Impingement (FAI) surgery) requiring moderate capsulotomy, would result in similar patient outcomes in the short, mid and long term, both…
- Trial name
- NCT02990234
- Testing
- Capsular Repair, No Capsular Repair
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Anxiety Disorders, Panic Disorder
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis
Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake…
- Conditions
- Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02476136
- Testing
- paroxetine, duloxetine, fluoxetine or venlafaxine
- Volunteers
- 8,800 people
- Sponsor
- prof. Peter de Jonge
Psychological Trauma
Facilitating Developmental Interactions With Children in Out-of-Home Care
The first goal of this single arm clinical trial is to develop the Developmental Interactions Workshop Series (DIWS). The second goal is to learn about the DIWS's acceptability, feasibility, and usefulness by implementing it in…
- Trial name
- NCT07283471
- Testing
- The Developmental Interaction Workshop Series (DIWS)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cornell University
Intentional Injury
A WrapAround Case Management Program for Youth Injured by Violence
This is a feasibility study of a WrapAround Case Management Program for Youth Injured by Violence. Youth (aged 10-24) who have been injured by violence and visit the emergency department will be offered a support worker who will…
- Trial name
- NCT01751464
- Testing
- WrapAround Case Management
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Manitoba
S100B, Neutrophils/Lymphocytes Ratio
Protein S100B Versus Neutrophils/Lymphocytes Ratio in Early Prediction of Brain Injury
The study aimed to evaluate the role of Protein S100B versus the neutrophil-to-lymphocyte ratio (NLR) as an early predictor biomarker and the value of amplitude-integrated electroencephalography (aEEG) as an early predictor and…
- Conditions
- S100B, Neutrophils/Lymphocytes Ratio, Prediction, Brain Injury
- Trial name
- NCT07093723
- Testing
- S100B Protein, Neutrophils to Lymphocytes ratio
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Post Operative Pain, Stress Response
Effects of Erector Spinae Plane and Caudal Block on Postoperative Stress Response
Inguinal hernia surgery is the most common practice of pediatric surgeons in their clinical practice. As these operations are usually day case procedures, maintaining adequate analgesia is an important component of perioperative…
- Conditions
- Post Operative Pain, Stress Response, Erector Spinae Plane Block, Caudal Block
- Trial name
- NCT05633173
- Testing
- Ultrasound-guided erector spinae plan block, Ultrasound-guided caudal block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hepatic Ischemic and Reperfusion Injury
Liver Protection of RIPC in Pediatric Living Donor Liver Transplantation
Remote ischemic preconditioning(RIPC) is emerging as an promising therapeutic paradigm to combat the detrimental impact of ischemic and reperfusion injury.
- Trial name
- RIPC-PLDT (NCT02830841)
- Testing
- remote ischemic preconditioning(RIPC)
- Where
- China
- Volunteers
- 208 people
- Sponsor
- RenJi Hospital
Respiratory Distress Syndrome (RDS), Bronchopulmonary Dysplasia (BPD)
Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?
The goal of this study is to determine if giving a steroid medication (specifically, betamethasone) after birth can help extremely premature babies (born before 28 weeks) come off breathing machines safely and reduce their risk…
- Trial name
- NCT07447739
- Testing
- Betamethasone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Khang Nguyen
Preeclampsia
ECLAXIR:Search for an Association Between CX3CR1 V249I Polymorphism, Preeclampsia and Endothelial Injury
The study hypothesis is the involvement of the couple CX3CR1/CX3CL1 in occurrence of endothelial injury in preeclampsia. According to this hypothesis, Carriers of the I249 allele who express less CX3CR1 shoud be protected against…
- Trial name
- NCT00190177
- Where
- France
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lower Limb Injury
IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery
IV and included steroids have produced the same length of block prolongation in adults as if the steroid was given with the nerve block. Clinically, this has not be noticed in children.
- Trial name
- NCT03855059
- Testing
- Dexamethasone Sodium Phosphate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arizona
Safety Issues, Effect of Drugs
The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells
To study the safety and effect of autologous umbilical cord blood stem cells for treatment brain injury
- Trial name
- NCT03696745
- Testing
- autologous umbilical cord blood stem cells, 0.9% Sodium-chloride
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
The first 5,000 results can be paged through. Add a filter or change the sort order to reach the rest.