Clinical trials: Injuries
Knee Osteoarthritis, Hip Osteoarthritis
Comparison of Knotless Barbed Suture and Standard Suture in Knee Replacement Patients
Barbed suture use has been gaining increased acceptance and has been reported to offer potential advantages in wound closure of hip and knee replacement surgeries.
- Trial name
- NCT03031314
- Testing
- barbed suture, standard suture
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Washington Hospital Healthcare System
Drug Use, Drug Abuse
Acute Intervention to Reduce Distress Following Sexual Assault
The purpose of this study was to evaluate whether a brief intervention in video format delivered in the post assault medical exam setting and including education about assault reactions and instruction in and modeling of…
- Conditions
- Drug Use, Drug Abuse, Posttraumatic Stress Disorder
- Trial name
- NCT01622855
- Testing
- PPRS
- Where
- United States
- Volunteers
- 442 people
- Sponsor
- Medical University of South Carolina
Tibial Fractures
Management of Closed Diaphyseal Displaced Leg Fractures in Children and Adolescents
Most displaced tibial shaft fractures in pediatric patients have traditionally been treated after reduction by cast immobilization with good long-term results.
- Trial name
- FFD (NCT06503718)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Strasbourg, France
Tendon Injuries
The Manchester Short Splint in the Rehabilitation of Zone II Flexor Tendon Repairs
The project sets out to compare two different splints in the outcome of zone II flexor tendon injury hand therapy rehabilitation programme.
- Trial name
- Short Splint (NCT03850210)
- Testing
- Short Splint, Traditional Long Splint
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Manchester University NHS Foundation Trust
Burns
Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients
The purpose of this study is to determine whether either a peripheral nerve block under ultrasound (u/s) guidance of the lateral femoral cutaneous nerve (LFCN), versus an u/s guided block of the nerve followed by continuous…
- Trial name
- NCT01500655
- Testing
- Regional nerve block, Catheter
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts General Hospital
Peripheral Nerve Injury Upper Limb
Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study
The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults.
- Trial name
- NCT06638008
- Testing
- perineural injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Traumatic Optic Neuropathy
Traumatic Optic Neuropathy Treatment Trial (TONTT)
The pathophysiology of Traumatic Optic Neuropathy (TON) is thought to be multifactorial, and some researchers have also postulated a primary and secondary mechanism of injury.TON is categorized as direct or indirect.In indirect…
- Trial name
- TONTT (NCT01783847)
- Testing
- Recombinant human erythropoietin (EPO), Observation, Methyl prednisolone
- Where
- 3 sites in Iran
- Volunteers
- 117 people
- Sponsor
- Tehran University of Medical Sciences
Fracture Wrist
Comparative Trial of Operative Treatment of Distal Pediatric Forearm Fractures With Biodegradable Nails and K-wires
The study is designed as a multicenter trial for the treatment of distal pediatric forearm fractures (=severely displaced distal metaphyseal forearm fractures) with a PLGA-based biodegradable intramedullary implant in children.
- Trial name
- NCT04848818
- Testing
- Distal radial metaphyseal fracture fixation with percutaneous K-wires, Distal radial and/or ulnar metaphyseal fracture fixation with bidegradable PLGA-based (Activa Im-Nail) implants
- Where
- 4 sites in Hungary
- Volunteers
- 164 people
- Sponsor
- Péterfy Sándor Hospital
Concussion
Concussion Testing: A Novel Non-invasive Concussion Detection Device
The purpose of this study is to establish and evaluate a distinctive signal for concussion.
- Trial name
- NCT02370914
- Testing
- Nautilus NeuroWaveTM System, SCAT
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
Orthopedic Disorders, Surgical Site Infection
Preoperative Decolonization and Surgical Site Infections - a Prospective Randomized Trial
Surgical site infections are a major postoperative complication and are mostly due to colonization with endogenous germs, like Staphylococcus aureus, Staphylococcus epidermidis or Propionibacterium acnes.
- Trial name
- DECO-SSI (NCT02560155)
- Testing
- Mupirocin 2% nasal ointement, Chlorhexidine sol 4%
- Where
- Switzerland
- Volunteers
- 1,300 people
- Sponsor
- Lindenhofgruppe AG
Injury, Spinal Cord
Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
This is a randomized, controlled, single-blind, multicenter, two Arm (Treatment or "Scaffold" Arm; Standard of Care or "Comparator" Arm) of a Neuro-Spinal Scaffold to evaluate whether the Scaffold is safe and demonstrates…
- Trial name
- INSPIRE 2 (NCT03762655)
- Testing
- Neuro-Spinal Scaffold
- Where
- 16 sites in United States
- Volunteers
- 20 people
- Sponsor
- InVivo Therapeutics
Head Injuries With Non Missile Penetrating Objjects
Non-missile Penetrating Head Trauma,Cases Registry in Sohag University Hospital
A retrospective study was done in Neurosurgery trauma unit, Sohag University. Eighteen patients reported with different mechanisms of trauma. All patients clinically tested involving neurological evaluation.
- Trial name
- trauma (NCT03768778)
- Testing
- Debridement and dural repair
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sohag University
PreTerm Neonate, Extubation Readiness
Prospective Multicentre Mixed Methods Study to Explore Extubation Practices and Respiratory Outcomes in Extremely Preterm Neonates.
The purpose of this observational study is to learn about neonatologists' perceptions of extubation readiness and extubation and reintubation practices in extremely preterm infants in the first 2 weeks of life using prospective…
- Conditions
- PreTerm Neonate, Extubation Readiness, Extubation Failure, Respiratory Morbidity
- Trial name
- CERAINE (NCT06808997)
- Where
- 31 sites in France
- Volunteers
- 166 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Dental Caries in Children, Wound Heal
Biostimulation After Tooth Extraction
This study evaluated the effect of low-level laser therapy on postoperative pain and wound healing in children undergoing primary molar extractions 40children, 6-10 years of age, systemically healthy, and had atraumatic…
- Trial name
- NCT06018584
- Testing
- Tooth extraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hazal Özer
Knee Injuries
Meniscal Root Tears: Evaluation Using an Ultrahigh MRI
Meniscal root tears have been recently recognized to be one of the most common causes for the progression of arthritis in relatively young patients.
- Trial name
- NCT05088525
- Testing
- MRI
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
Rotator Cuff Tears
Superior Capsular Reconstruction Versus. Partial Repair for Irreparable Rotator Cuff Tears
Rotator cuff tear is one of the common injuries that cause shoulder pain in the elderly. After the rotator cuff tendon is injured, repairing the torn rotator cuff tendon through arthroscopic surgery is an effective treatment that…
- Trial name
- NCT04584476
- Testing
- superior capsular reconstuction, partial rotator cuff repair
- Volunteers
- 20 people
- Sponsor
- Beijing Jishuitan Hospital
Motor Vehicle Injury
Traffic Safety Study at Calgary Elementary Schools
Installing specific traffic calming features designed to reduce vehicle speed and volume around schools may lead to a reduction in injury risk for child pedestrians and bicyclists, and may increase numbers of children walking and…
- Trial name
- NCT04956250
- Testing
- Traffic Calming Curbs, In-Street Pedestrian Sign
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Calgary
Inhalation Anesthesia
Comparing Nebulized Ketamine,Nebulized Ketamine and Precedex and IM Ketamine for Analgesia in Pediatric Burn
The present study compares efficacy of nebulised ketamine and combination of nebulised dexmedetomidine and ketamine and intramuscular ketamine for procedural sedation and analgesia in pediatric burn injuries
- Trial name
- NCT07086690
- Testing
- Group (1): Patients will receive nebulized ketamine (2 mg/kg), Group (2): Patients will receive nebulized combination of dexmedetomidine and ketamine (1 μg/kg + 1 mg/kg), Patients will receive intramuscular ketamine (4 mg/kg, intramuscularly) 15 mins before starting the procedure.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Injuries, Spinal Cord
Clinical Trial to Evaluate One-to-one Peer Mentoring
The research will examine the effects of enhanced peer mentor interactions on facilitating a successful transition to community living following traumatic spinal cord injury (SCI).
- Trial name
- NCT02274649
- Testing
- one-to-one peer mentoring, general peer support
- Volunteers
- 194 people
- Sponsor
- Shepherd Center, Atlanta GA
Child Sexual Abuse, Post-Traumatic Stress Disorder, PTSD
Intensive Inpatient Trauma-Focused Cognitive Behavioral Therapy (II-TF-CBT) for Adolescents With PTSD Following Sexual Abuse
This study looks at a treatment program for children and teens who have post-traumatic stress disorder (PTSD) after sexual abuse. The program is called II-TF-CBT.
- Trial name
- NCT07732335
- Testing
- II-TF-CBT
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
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